期刊
BIOPROCESS AND BIOSYSTEMS ENGINEERING
卷 45, 期 7, 页码 1201-1210出版社
SPRINGER
DOI: 10.1007/s00449-022-02736-6
关键词
Dental caries; Streptococcus mutans; Biosynthesis; NiO nanoparticles; Bacteriostatic activity
资金
- King Saud University, Riyadh, Saudi Arabia [RSP-2021/364]
Dental decay is the most common human infectious disease, and nanomaterials hold promise for antimicrobial and antiviral applications.
Dental decay is known in the world as the most common human infectious disease. Ascending process of dental caries index in the world shows the failure of oral disease prevention. Streptococcus mutans bacteria cause acid damage and tooth decay by producing acid over time. Nanomaterials with suitable functionality, high permeability, extremely large surface area, significant reactivity, unique mechanical features, and non-bacterial resistance can be considered as promising agents for antimicrobial and antiviral applications. In this study, nickel oxide (NiO) nanoparticles with size range from 2 to 16 nm containing Stevia natural sweetener were eco-friendly synthesized via a simple method. Additionally, their various concentrations were evaluated on S. mutans bacteria by applying the broth dilution method. The results demonstrated that these spherical NiO nanoparticles had efficient bacteriostatic activity on this gram-positive coccus. [GRAPHICS] .
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