4.7 Article

Flashfm-ivis: interactive visualization for fine-mapping of multiple quantitative traits

期刊

BIOINFORMATICS
卷 38, 期 17, 页码 4238-4242

出版社

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btac453

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资金

  1. UK Medical Research Council [MR/L003120/1, MR/R021368/1, MC_UU_00002/4]
  2. Alan Turing Institute and British Heart Foundation [SP/18/5/33804]
  3. NIHR Blood and Transplant Research Unit in Donor Health and Genomics [NIHR BTRU-2014-10024]
  4. British Heart Foundation [SP/09/002, RG/13/13/30194, RG/18/13/33946]
  5. NIHR Cambridge BRC [BRC-1215-20014]

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flashfm-ivis provides an interactive visualization tool to view potential causal genetic variants and compare associations between different quantitative traits. Its unique features, such as network diagrams and regional association plots, allow users to explore the joint effects across traits.
flashfm-ivis provides a suite of interactive visualization plots to view potential causal genetic variants that underlie associations that are shared or distinct between multiple quantitative traits and compares results between single- and multi-trait fine-mapping. Unique features include network diagrams that show joint effects between variants for each trait and regional association plots that integrate fine-mapping results, all with user-controlled zoom features for an interactive exploration of potential causal variants across traits.

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