ZnFe2O4@SiO2-ascorbic acid: Green, magnetic, and versatile catalyst for the synthesis of chromeno[2,3-d] pyrimidine-8-amine and quinazoline derivatives

In this research project, silica-modified ZnFe2O4 magnetic nanoparticles were prepared in a simple, short, and straightforward way. Subsequently, an efficient catalyst through immobilization of ascorbic acid on the surface of silica-coated ZnFe2O4 nanoparticles has been produced. The physical and chemical properties of ZnFe2O4@SiO2-ascorbic acid were considered by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), Energy-dispersive X-ray spectroscopy (EDS), and vibrating sample magnetometer (VSM) analyses. The catalytic activity of described magnetic nanocatalyst was checked out for the synthesis of chromeno[2,3-d] pyrimidine-8-amine and quinazolinone derivatives. The described catalyst was recovered and reused for five continuous cycles without considerable change in its catalytic activity.

Automated summary

In this research project, silica-modified ZnFe2O4 magnetic nanoparticles were prepared and immobilized with ascorbic acid to produce an efficient catalyst. The physical and chemical properties of the catalyst were analyzed, and its catalytic activity was tested for the synthesis of specific derivatives. The catalyst showed good recyclability.