Sulfur-Phenolate Exchange: SuFEx-Derived Dynamic Covalent Reactions and Degradation of SuFEx Polymers

The products of the SuFEx reaction between sulfonimidoyl fluorides and phenols, sulfonimidates, are shown to display dynamic covalent chemistry with other phenols. This reaction was shown to be enantiospecific, finished in minutes at room temperature in high yields, and useful for both asymmetric synthesis and sustainable polymer production. Its wide scope further extends the usefulness of SuFEx and related click chemistries.

Automated summary

The SuFEx reaction between sulfonimidoyl fluorides and phenols, sulfonimidates, exhibits dynamic covalent chemistry with other phenols. This enantiospecific reaction can be completed at room temperature within minutes and with high yields, making it useful for asymmetric synthesis and sustainable polymer production. Its broad scope further extends the applications of SuFEx and related click chemistries.