相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Processed meat consumption and the risk of incident late-onset depression: a 12-year follow-up of the Salus in Apulia Study
Luisa Lampignano et al.
AGE AND AGEING (2022)
A critical appraisal of tau-targeting therapies for primary and secondary tauopathies
Bruno P. Imbimbo et al.
ALZHEIMERS & DEMENTIA (2022)
Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer's disease risk in humans
Yiyi Ma et al.
ALZHEIMERS & DEMENTIA (2022)
APOE Antibody Inhibits Aβ-Associated Tau Seeding and Spreading in a Mouse Model
Maud Gratuze et al.
ANNALS OF NEUROLOGY (2022)
Design and Validation of Liposomal ApoE2 Gene Delivery System to Evade Blood-Brain Barrier for Effective Treatment of Alzheimer's Disease
Sanjay Arora et al.
MOLECULAR PHARMACEUTICS (2021)
Microglia and lipids: how metabolism controls brain innate immunity
Bruno Chausse et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2021)
Untangling the association of amyloid-beta and tau with synaptic and axonal loss in Alzheimer's disease
Joana B. Pereira et al.
BRAIN (2021)
Apolipoprotein E4 Reduction with Antisense Oligonucleotides Decreases Neurodegeneration in a Tauopathy Model
Alexandra Litvinchuk et al.
ANNALS OF NEUROLOGY (2021)
Expression and secretion of apoE isoforms in astrocytes and microglia during inflammation
Maria Fe Lanfranco et al.
GLIA (2021)
APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia
Chia-Chen Liu et al.
SCIENCE TRANSLATIONAL MEDICINE (2021)
APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function
Monica Xiong et al.
SCIENCE TRANSLATIONAL MEDICINE (2021)
Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia
Chao Wang et al.
NEURON (2021)
APOE genotype moderates the relationship between LRP1 polymorphism and cognition across the Alzheimer's disease spectrum via disturbing default mode network
Feifei Zang et al.
CNS NEUROSCIENCE & THERAPEUTICS (2021)
Inflammatory Pathways Are Impaired in Alzheimer Disease and Differentially Associated With Apolipoprotein E Status
Courtney M. Kloske et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2021)
Regulation of beta-amyloid production in neurons by cholesterol
Hao Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and AB generation
Se-In Lee et al.
STEM CELL REPORTS (2021)
ApoE mimetic improves pathology and memory in a model of Alzheimer's disease
Kamesh Krishnamurthy et al.
BRAIN RESEARCH (2020)
Apolipoprotein E (APOE) genotype-associated disease risks: a phenome-wide, registry-based, case-control study utilising the UK Biobank
Amanda L. Lumsden et al.
EBIOMEDICINE (2020)
Symptomatic amyloid-related imaging abnormalities in an APOE ε4/ε4 patient treated with aducanumab
Lawren VandeVrede et al.
ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING (2020)
Dr. Jekyll and Mr. Hyde: ApoE explains opposing effects of neuronal LRP1
Michael R. Strickland et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1
Masaya Tachibana et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
APOE genotype influences the gut microbiome structure and function in humans and mice: relevance for Alzheimer's disease pathophysiology
Tam T. T. Tran et al.
FASEB JOURNAL (2019)
The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques
Carlo Sala Frigerio et al.
CELL REPORTS (2019)
Time to test antibacterial therapy in Alzheimer's disease
Francesco Panza et al.
BRAIN (2019)
Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy
Tiffany Wu et al.
CELL REPORTS (2019)
APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types
Yuan-Ta Lin et al.
NEURON (2018)
AAVrh.10-Mediated APOE2 Central Nervous System Gene Therapy for APOE4-Associated Alzheimer's Disease
Jonathan B. Rosenberg et al.
HUMAN GENE THERAPY CLINICAL DEVELOPMENT (2018)
The cerebellum in Alzheimer's disease: evaluating its role in cognitive decline
Heidi I. L. Jacobs et al.
BRAIN (2018)
APOE ε4/ε4 diminishes neurotrophic function of human iPSC-derived astrocytes
Jing Zhao et al.
HUMAN MOLECULAR GENETICS (2017)
Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis
Tien-Phat V. Huynh et al.
NEURON (2017)
Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes
Na Zhao et al.
NEURON (2017)
Alzheimer's disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation
Wilbur Song et al.
ALZHEIMERS & DEMENTIA (2017)
APOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer's disease
J. I. Velez et al.
MOLECULAR PSYCHIATRY (2016)
The Cellular Phase of Alzheimer's Disease
Bart De Strooper et al.
CELL (2016)
An Anti-apoE4 Specific Monoclonal Antibody Counteracts the Pathological Effects of apoE4 In Vivo
Ishai Luz et al.
CURRENT ALZHEIMER RESEARCH (2016)
Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models
Lingzhi Zhao et al.
NEUROBIOLOGY OF AGING (2016)
Long-term episodic memory decline is associated with olfactory deficits only in carriers of ApoE-ε4
Jonas K. Olofsson et al.
NEUROPSYCHOLOGIA (2016)
Complement and microglia mediate early synapse loss in Alzheimer mouse models
Soyon Hong et al.
SCIENCE (2016)
Impaired vascular-mediated clearance of brain amyloid beta in Alzheimer's disease: the role, regulation and restoration of LRP1
Anita Ramanathan et al.
FRONTIERS IN AGING NEUROSCIENCE (2015)
APOε4 is associated with enhanced in vivo innate immune responses in human subjects
Stephen C. Gale et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2014)
ApoE variant p.V236E is associated with markedly reduced risk of Alzheimer's disease
Christopher W. Medway et al.
MOLECULAR NEURODEGENERATION (2014)
Blocking the Interaction between Apolipoprotein E and Aβ Reduces Intraneuronal Accumulation of Aβ and Inhibits Synaptic Degeneration
Magdalena A. Kuszczyk et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
Chia-Chan Liu et al.
NATURE REVIEWS NEUROLOGY (2013)
The Apolipoprotein-E-Mimetic COG112 Protects Amyloid Precursor Protein Intracellular Domain-Overexpressing Animals from Alzheimer's Disease-Like Pathological Features
Kaushik Ghosal et al.
NEURODEGENERATIVE DISEASES (2013)
The forgotten APOE allele: A review of the evidence and suggested mechanisms for the protective effect of APOE ε2
Sana Suri et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2013)
Gene Transfer of Human Apoe Isoforms Results in Differential Modulation of Amyloid Deposition and Neurotoxicity in Mouse Brain
Eloise Hudry et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Cerebrovascular Effects of Apolipoprotein E Implications for Alzheimer Disease
Berislav V. Zlokovic
JAMA NEUROLOGY (2013)
Longitudinal modeling of cognitive aging and the TOMM40 effect
Richard J. Caselli et al.
ALZHEIMERS & DEMENTIA (2012)
Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β
Robert M. Koffie et al.
BRAIN (2012)
Small Molecule Structure Correctors Abolish Detrimental Effects of Apolipoprotein E4 in Cultured Neurons
Hung-Kai Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aβ amyloidosis
Jungsu Kim et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Small-Molecule Structure Correctors Target Abnormal Protein Structure and Function: Structure Corrector Rescue of Apolipoprotein E4-Associated Neuropathology
Robert W. Mahley et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
Robert D. Bell et al.
NATURE (2012)
APOE-Mimetic Peptides Reduce Behavioral Deficits, Plaques and Tangles in Alzheimer's Disease Transgenics
M. P. Vitek et al.
NEURODEGENERATIVE DISEASES (2012)
Apolipoprotein E4 Domain Interaction Mediates Detrimental Effects on Mitochondria and Is a Potential Therapeutic Target for Alzheimer Disease
Hung-Kai Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Structure-dependent Impairment of Intracellular Apolipoprotein E4 Trafficking and Its Detrimental Effects Are Rescued by Small-molecule Structure Correctors
Jens Brodbeck et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Apolipoprotein E: Isoform Specific Differences in Tertiary Structure and Interaction with Amyloid-β in Human Alzheimer Brain
Phillip B. Jones et al.
PLOS ONE (2011)
ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling
Ying Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
APOE and cholesterol homeostasis in Alzheimer's disease
Valerie Leduc et al.
TRENDS IN MOLECULAR MEDICINE (2010)
Apolipoprotein E knockout models
Genovefa Kolovou et al.
CURRENT PHARMACEUTICAL DESIGN (2008)
Brain metabolic decreases related to the dose of the ApoE e4 allele in Alzheimer's disease
L Mosconi et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2004)
Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-β peptides
M Koistinaho et al.
NATURE MEDICINE (2004)
Apolipoprotein E4 domain interaction occurs in living neuronal cells as determined by fluorescence resonance energy transfer
Q Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Lipoprotein(a), apolipoprotein E genotype, and risk of Alzheimer's disease
V Solfrizzi et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2002)
Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene
DA Nickerson et al.
GENOME RESEARCH (2000)
分享论文
