Palladium-Catalyzed Synthesis of Carbazoles by Perester

An intramolecular C-H amination for the synthesis of carbazoles with a Pd(II)/TBPB system has been developed. This catalytic amination process forms the carbazole products in good to excellent yields. It is noteworthy that this method implied the advantages of the catalytic mode involving perester with transition metal catalyst in the activation of inert C-H bonds. In addition, the transformation performs well using water as solvent.

Automated summary

An intramolecular C-H amination for the synthesis of carbazoles with a Pd(II)/TBPB system has been developed. This method forms carbazole products in good to excellent yields. Notably, the use of water as solvent in this catalytic process is also effective.