Temporomandibular disorders and neck pain in primary headache patients: a retrospective machine learning study

Objectives To evaluate the linkage underpinning different clinical conditions as painful TMD and neck pain in patients affected by primary headaches. Materials and methods In this machine learning study, data from medical records of patients with headaches as migraine, tension-type headache (TTH) and other primary ones, referring to a University Hospital over a 10-year period were analysed. VAS was used to evaluate the intensity of the TMD and neck pain. Moreover, the magnetic resonance imaging was used to supplement the clinical data. Results A total of 300 patients (72 male, 228 female), mean aged 37.78 +/- 5.11 years, were included. Higher TMD and neck pain VAS in migraine patients were reported. The machine learning analysis focussed on type of primary headache demonstrated that a higher TMD VAS was correlated to migraine, whereas a higher neck pain VAS was correlated to TTH or migraine. Concerning the TMD type, arthrogenous and mixed TMD were correlated to mild-moderate TMD pain (depending on neck pain intensity), whereas myogenic TMD was correlated to moderate-severe TMD pain. Conclusions Machine-learning approach highlighted the complexity of diagnosis process and demonstrated that neck pain might be an influential variable on the belonging to different group of headaches in TMD patients.

Automated summary

This study evaluated the association between temporomandibular disorder (TMD) and neck pain in patients with primary headaches. The results showed that migraine patients reported higher TMD and neck pain. Machine learning analysis demonstrated that TMD was correlated to migraine, while neck pain was correlated to tension-type headache (TTH) or migraine.