期刊
DERMATOPATHOLOGY
卷 9, 期 2, 页码 136-142出版社
MDPI
DOI: 10.3390/dermatopathology9020017
关键词
spitz nevus; atypical spitz tumor; spitz melanoma; dermatopathology
类别
This article provides a historical perspective and a summary of current knowledge and clinical approaches for Spitz neoplasms, including Spitz nevi, atypical Spitz Tumors, and Spitz melanoma.
Over the past several decades, the study of Spitz neoplasms has flourished, with expanded conceptualization and refined terminology, providing a framework for the assessment and classification of Spitz nevi, atypical Spitz Tumors, and Spitz melanoma. Cancer genomics have generated concepts such as driver and passenger genes and clonal evolution, which can be applied to Spitz tumors. Herein, we provide a historical perspective, followed by a summary of current knowledge and clinical approaches for these challenging tumors.
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