Peripheral dentinogenic ghost cell tumor in the mandibular anterior region

A dentinogenic ghost cell tumor (DGCT), the rarest locally invasive odontogenic tumor, is considered a solid variant of the calcifying odontogenic cyst. Histopathologically, DGCT is characterized by ameloblastoma-like islands of epithelial cells in a mature connective tissue stroma and aberrant keratinization in the form of ghost cells associated with varying amounts of dysplastic dentin. DGCT is classified into the intraosseous type (central) and the extraosseous type (peripheral). The peripheral type is even rarer than the central type. We describe a case of peripheral DGCT measuring a size of 33 x 28 x 19 mmin the mandibular anterior region in a 61-year old woman. The tumor was diagnosed as a peripheral DGCT based on biopsy findings and radiographic images. Under general anesthesia, the lesion was excised by detaching it from the bone on the periosteum with a safety margin, and the bone in contact with the tumor was curetted and shaped. The wound was covered with poly glycolic acid-absorbable reinforcement material and fibrin glue spray. At approximately one year postoperatively, the patient remains recurrence-free.

Automated summary

Dentinogenic ghost cell tumor (DGCT) is a rare odontogenic tumor characterized by islands of epithelial cells and ghost cells. It can be classified as intraosseous or extraosseous, with the peripheral type being even rarer. We present a case of peripheral DGCT in a 61-year-old woman, which was successfully treated with surgery and showed no recurrence after one year.