期刊
JOURNAL OF ANALYSIS AND TESTING
卷 6, 期 2, 页码 204-215出版社
SPRINGER SINGAPORE PTE LTD
DOI: 10.1007/s41664-022-00220-4
关键词
Formaldehyde; Small molecule probe; Fluorescence detection; Environmental monitoring; Intracellular analysis; In vivo imaging
资金
- National Natural Science Foundation of China [22074005]
- Natural Science Foundation of Beijing Municipality [2202038]
- Open Research Fund Program of Beijing Key Lab of Plant Resource Research and Development, Beijing Technology and Business University [PRRD-2021-YB6]
This review provides a comprehensive summary of recent research on fluorescent analysis of formaldehyde using small molecule probes. It discusses the sensing mechanisms, detection methods, and performance in various environments, as well as the challenges and future trends in formaldehyde detection based on fluorescent probes.
Formaldehyde (FA, a typical reactive carbonyl species) is a well-known environmental pollutant and a disease-related biomarker, making its sensitive and selective detection significant. Fluorescent probes have been explored for FA perception in environment, intracellular media and in vivo. In this review, we majorly conclude the recently represented fluorescence FA analysis based on small molecule probes. The general FA sensing mechanisms are first introduced. Regarding the FA detection in various environments, sensing tactics and performances are discussed in order of natural environment, living cells and in vivo. In the end, this review discusses the challenges and future trends of FA detection based on fluorescent probes.
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