期刊
CLINICAL AND EXPERIMENTAL REPRODUCTIVE MEDICINE-CERM
卷 49, 期 1, 页码 2-8出版社
KOREAN SOC REPRODUCTIVE MEDICINE
DOI: 10.5653/cerm.2022.05225
关键词
Assisted reproductive technology; COVID-19; Lactation; Pregnancy; Vaccination
Based on laboratory and clinical data, it is recommended to administer COVID-19 vaccines to individuals undergoing ART treatment and pregnant women. The vaccines do not have adverse effects on embryos, pregnant women, and breastfeeding infants, and can deliver antibodies through breastfeeding.
Humanity is in the midst of the coronavirus disease 2019 (COVID-19) pandemic, and vaccines-including mRNA vaccines-have been developed at an unprecedented speed. It is necessary to develop guidelines for vaccination for people undergoing treatment with assisted reproductive technology (ART) and for pregnancy-related situations based on the extant laboratory and clinical data. COVID-19 vaccines do not appear to adversely affect gametes, embryos, or implantation; therefore, active vaccination is recommended for women or men who are preparing for ART. The use of intravenous immunoglobulin G (MG) for the treatment of immune-related infertility is unlikely to impact the effectiveness of the vaccines, so COVID-19 vaccines can be administered around ART cycles in which NIG is scheduled. Pregnant women have been proven to be at risk of severe matemal and neonatal complications from COVID-19.It does not appear that COVID-19 vaccines harm pregnant women or fetuses; instead, they have been observed to deliver antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to the fetus. Accordingly, it is recommended that pregnant women receive COVID-19 vaccination. There is no rationale for adverse effects, or clinical cases of adverse reactions, in mothers or neonates after COVID-19 vaccination in lactating women. Instead, antibodies to SARS-CoV-2 can be delivered through breast milk.Therefore, breastfeeding mothers should consider vaccination. In summary, active administration of COVID-19 vaccines will help ensure the safe implementation of ART, pregnancy, and breastfeeding.
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