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Laura F. McNair et al.
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Regina Hertfelder Reynolds et al.
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Whitney Franklin et al.
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James Hamilton et al.
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Maria Hvidberg Petersen et al.
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Jia Yao et al.
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Heather J. M. Weir et al.
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Martin D. Brand et al.
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Maria Damiano et al.
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Martin Jastroch et al.
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Ina Han et al.
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Randa Tao et al.
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P. Hemachandra Reddy et al.
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Andrey V. Kuznetsov et al.
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Sung W. Choi et al.
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Huan Ma et al.
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Sarah J. Tabrizi et al.
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Jianjun Wang et al.
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Kimberly J. Harms et al.
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Adam L. Orr et al.
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Christoph Loenarz et al.
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Dmitry Lim et al.
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Kranthi Kumari Naga et al.
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L. I. Johnson-Cadwell et al.
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Laura Conforti et al.
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MR Brown et al.
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D. T. W. Chang et al.
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SAJ Reading et al.
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XF Guo et al.
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Z Li et al.
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W Pendergrass et al.
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H Li et al.
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