☆ 4.3 Article

Factors influencing estimated effectiveness of COVID-19 vaccines in non-randomised studies

BMJ EVIDENCE-BASED MEDICINE (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Editorial Material Medicine, General & Internal

Transparency of COVID-19 vaccine trials: decisions without data

Sarah Tanveer et al.

BMJ EVIDENCE-BASED MEDICINE (2022)

添加到收藏夹

Review Multidisciplinary Sciences

Vaccines to prevent COVID-19: A living systematic review with Trial Sequential Analysis and network meta-analysis of randomized clinical trials

Steven Kwasi Korang et al.

Summary: This study assessed the effectiveness and safety of COVID-19 vaccines through analyses of randomized clinical trials. The findings suggest that all included vaccines are effective in preventing COVID-19, with mRNA vaccines being most effective in prevention and viral vector vaccines being most effective in reducing mortality. However, further trials and longer follow-up are needed to better understand the safety profile of these vaccines.

PLOS ONE (2022)

添加到收藏夹

Review Environmental Sciences

SARS-CoV-2 reinfections: Overview of efficacy and duration of natural and hybrid immunity

Stefan Pilz et al.

Summary: Seroprevalence surveys indicate that a significant proportion of the global population has been infected with SARS-CoV-2, and natural immunity plays a crucial role in protecting against reinfections and severe disease. National surveys show that previous infection provides a reduced risk of reinfection for at least one year, with moderate waning immunity. Natural immunity appears to have similar effectiveness against different SARS-CoV-2 variants, except for the Omicron variant which requires further study. Observational studies suggest that natural immunity may provide equal or greater protection compared to two doses of mRNA vaccines, although data are not consistent. Combining previous infection with vaccination seems to offer the greatest protection against SARS-CoV-2, but there are still knowledge gaps in this area.

ENVIRONMENTAL RESEARCH (2022)

添加到收藏夹

Review Infectious Diseases

Update on SARS-CoV-2 seroprevalence: regional and worldwide

Ali Rostami et al.

Summary: This study conducted a global systematic review and meta-analysis to estimate the global and regional SARS-CoV-2 seroprevalences, finding a global pooled seroprevalence of approximately 9.47% with significant heterogeneity. The highest and lowest seroprevalences were observed in Central and Southern Asia, as well as Eastern and South-eastern Asia. The study suggests that by mid-2021, the majority of the world's population remained highly susceptible to SARS-CoV-2 infection.

CLINICAL MICROBIOLOGY AND INFECTION (2021)

添加到收藏夹

Review Public, Environmental & Occupational Health

How to detect and reduce potential sources of biases in studies of SARS-CoV-2 and COVID-19

Emma K. Accorsi et al.

Summary: In response to the COVID-19 pandemic, public health scientists have produced a large body of literature, but observational studies may be biased due to confounding, selection bias, and measurement error. To accurately evaluate these studies and guide future research design, attention needs to be paid to and solutions proposed for potential biases.

EUROPEAN JOURNAL OF EPIDEMIOLOGY (2021)

添加到收藏夹

Review Cell Biology

Development and deployment of COVID-19 vaccines for those most vulnerable

Wayne C. Koff et al.

Summary: The development and global deployment of COVID-19 vaccines are crucial in ending the pandemic, but challenges remain in elderly populations and low-resource settings, making distribution and vaccination efforts difficult.

SCIENCE TRANSLATIONAL MEDICINE (2021)

添加到收藏夹

Review Immunology

International estimates of intended uptake and refusal of COVID-19 vaccines: A rapid systematic review and meta-analysis of large nationally representative samples

Eric Robinson et al.

Summary: The global willingness to uptake COVID-19 vaccines is decreasing while refusal to vaccinate is increasing. Factors such as gender, age, lower income and education levels, and belonging to ethnic minority groups are associated with lower intentions to vaccinate.

VACCINE (2021)

添加到收藏夹

Article Geriatrics & Gerontology

The demography and characteristics of SARS-CoV-2 seropositive residents and staff of nursing homes for older adults in the Community of Madrid: the SeroSOS study

Francisco Javier Candel et al.

Summary: The study highlights the high prevalence of COVID-19 among residents in nursing homes, especially those who are frail and have comorbidities. Factors associated with seropositivity among staff include age, obesity, job type, workplace seroprevalence, and contact with external COVID-19 cases. Strengthening control measures is crucial to prevent COVID-19 transmission in care facilities.

AGE AND AGEING (2021)

添加到收藏夹

Article Public, Environmental & Occupational Health

Theoretical Framework for Retrospective Studies of the Effectiveness of SARS-CoV-2 Vaccines

Joseph A. Lewnard et al.

Summary: Observational studies on COVID-19 vaccine effectiveness face challenges such as misclassification and confounding, which should be addressed through practical strategies at both study design and analysis stages to reduce bias. Traditional case-control and test-negative design studies may encounter important threats to validity, particularly in the context of SARS-CoV-2 infection and COVID-19 natural history parameters.

EPIDEMIOLOGY (2021)

添加到收藏夹

Review Medicine, General & Internal

Reconciling estimates of global spread and infection fatality rates of COVID-19: An overview of systematic evaluations

John P. A. Ioannidis

Summary: This study reviewed six systematic evaluations on the global spread and infection rate of COVID-19, finding a consensus on SARS-CoV-2 infection being widely spread globally with an average IFR of about 0.15% and an estimated 1.5-2.0 billion infections. The research highlights substantial differences in IFR and infection spread across continents, countries, and locations.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2021)

添加到收藏夹

Review Immunology

Worldwide Vaccination Willingness for COVID-19: A Systematic Review and Meta-Analysis

Kimberly R. Nehal et al.

Summary: Global willingness to vaccinate against COVID-19 is estimated at 66.01%, but varies between countries and regions. Vaccine acceptance or refusal is significantly associated with factors such as age, gender, education, attitudes, and perceptions about vaccines.

VACCINES (2021)

添加到收藏夹

Review Immunology

Effectiveness of the WHO-Authorized COVID-19 Vaccines: A Rapid Review of Global Reports till 30 June 2021

Chang-Jie Cheng et al.

Summary: The rapid review indicated a consistently high effectiveness of certain vaccines among the general population in real-world settings. However, the scarcity of data on major variants of SARS-CoV-2 and the short study time may limit the conclusions to mRNA vaccines and ChAdOx1.

VACCINES (2021)

添加到收藏夹

Letter Medicine, General & Internal

Protective Behaviors Against COVID-19 by Individual Vaccination Status in 12 Countries During the Pandemic

Rafael Goldszmidt et al.

JAMA NETWORK OPEN (2021)

添加到收藏夹

Editorial Material Geriatrics & Gerontology

COVID-19 vaccination and frailty in older adults

Liang-Kung Chen

ARCHIVES OF GERONTOLOGY AND GERIATRICS (2021)

添加到收藏夹

Article Public, Environmental & Occupational Health

Over- and under-estimation of COVID-19 deaths

John P. A. Ioannidis

Summary: The ratio of COVID-19-attributable deaths versus true COVID-19 deaths depends on various factors and is currently leading to under-counting in some countries while possibly over-counting in others. Caution is needed in attributing deaths in syndemics like COVID-19.

EUROPEAN JOURNAL OF EPIDEMIOLOGY (2021)

添加到收藏夹

Article Immunology

Benefit of COVID-19 vaccination accounting for potential risk compensation

John P. A. Ioannidis

Summary: Receiving COVID-19 vaccines can reduce the risk of infection, but may lead to a marked increase in exposure risk. The benefits of vaccination are influenced by risk compensation, especially when vaccine efficacy is not very high.

NPJ VACCINES (2021)

添加到收藏夹

Article Immunology

Predictors of Test Positivity, Mortality, and Seropositivity during the Early Coronavirus Disease Epidemic, Orange County, California, USA

Daniel M. Parker et al.

Summary: A detailed analysis of coronavirus disease in a large population center in southern California revealed heterogeneity in risks for infection, test positivity, and death. Various factors such as age, race or ethnicity, and educational attainment in specific ZIP codes significantly affected the risk for seropositivity and death. The study also found that the pattern of case incidence shifted from high-income areas to lower socioeconomic status areas over time.

EMERGING INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Medicine, General & Internal

Prevalence of Antibodies to SARS-CoV-2 in Italian Adults and Associated Risk Factors

Antonio Vena et al.

JOURNAL OF CLINICAL MEDICINE (2020)

添加到收藏夹

Article Multidisciplinary Sciences

COVID-19 lockdown induces disease-mitigating structural changes in mobility networks

Frank Schlosser et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

添加到收藏夹

Article Public, Environmental & Occupational Health

Observational studies and the difficult quest for causality: lessons from vaccine effectiveness and impact studies

Marc Lipsitch et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2016)

添加到收藏夹

Article Infectious Diseases

The test-negative design: validity, accuracy and precision of vaccine efficacy estimates compared to the gold standard of randomised placebo-controlled clinical trials

G De Serres et al.

Eurosurveillance (2013)

添加到收藏夹

Review Immunology

Vaccine effects and impact of vaccination programmes in post-licensure studies

Germaine Hanquet et al.

VACCINE (2013)

添加到收藏夹

Article Immunology

The case test-negative design for studies of the effectiveness of influenza vaccine

Ivo M. Foppa et al.

VACCINE (2013)

添加到收藏夹

Article Immunology

The test-negative design for estimating influenza vaccine effectiveness

Michael L. Jackson et al.

VACCINE (2013)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.