期刊
MAGNETOCHEMISTRY
卷 8, 期 4, 页码 -出版社
MDPI
DOI: 10.3390/magnetochemistry8040038
关键词
nanohybrids; magnetic gold nanoparticles; nanocomposites; surface functionalization; core-shell nanocomposites; magnetic-plasmonic nanoparticles; biological applications
资金
- Beijing Natural Science Foundation [M22032]
Magnetic gold nanoparticles (mGNP) have attracted significant attention in biomedical applications due to their magnetic and plasmonic properties. This critical review summarizes recent developments in the synthesis and surface modification of mGNP, as well as their applications in drug and gene delivery, bioimaging, biosensing, and neuro-regeneration.
Magnetic gold nanoparticles (mGNP) have become a great interest of research for nanomaterial scientists because of their significant magnetic and plasmonic properties applicable in biomedical applications. Various synthetic approaches and surface modification techniques have been used for mGNP including the most common being the coprecipitation, thermal decomposition, and microemulsion methods in addition to the Brust Schiffrin technique, which involves the reduction of metal precursors in a two-phase system (water and toluene) in the presence of alkanethiol. The hybrid magnetic-plasmonic nanoparticles based on iron core and gold shell are being considered as potential theranostic agents. In this critical review, in addition to future works, we have summarized recent developments for synthesis and surface modification of mGNP with their applications in modern biomedical science such as drug and gene delivery, bioimaging, biosensing, and neuro-regeneration, neuro-degenerative and arthritic disorders. This review includes techniques and biological applications of mGNP majorly based on research from the previous six years.
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