Any Future for Faecal Microbiota Transplantation as a Novel Strategy for Gut Microbiota Modulation in Human and Veterinary Medicine?

Alterations in the composition of the intestinal microbiome, also known as dysbiosis, are the result of many factors such as diet, antibiotics, stress, diseases, etc. There are currently several ways to modulate intestinal microbiome such as dietary modulation, the use of antimicrobials, prebiotics, probiotics, postbiotics, and synbiotics. Faecal microbiota transplantation (FMT) represents one new method of gut microbiota modulation in humans with the aim of reconstructing the intestinal microbiome of the recipient. In human medicine, this form of bacteriotherapy is successfully used in cases of recurrent Clostridium difficile infection (CDI). FMT has been known in large animal medicine for several years. In small animal medicine, the use of FMT is not part of normal practice.

Automated summary

Alterations in intestinal microbiome composition, known as dysbiosis, can be influenced by diet, antibiotics, stress, and diseases. There are various methods to modulate the microbiome, including dietary changes, antimicrobials, prebiotics, probiotics, postbiotics, and synbiotics. Faecal microbiota transplantation (FMT) is a new method used to reconstruct the recipient's intestinal microbiome and has been successfully used in cases of recurrent Clostridium difficile infection (CDI) in human medicine. FMT has been used in large animal medicine for several years, but is not common in small animal medicine.