相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The Role of Lipids in Allosteric Modulation of Dopamine D2 Receptor-In Silico Study
Justyna Zuk et al.
MOLECULES (2022)
The Signaling and Pharmacology of the Dopamine D1 Receptor
Jace Jones-Tabah et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2022)
Axo-axonic synapses: Diversity in neural circuit function
Kara K. Cover et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2021)
Evaluation of Substituted N-Phenylpiperazine Analogs as D3 vs. D2 Dopamine Receptor Subtype Selective Ligands
Boeun Lee et al.
MOLECULES (2021)
Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist
Bingfa Sun et al.
NATURE COMMUNICATIONS (2021)
Serotonin Heteroreceptor Complexes and Their Integration of Signals in Neurons and Astroglia-Relevance for Mental Diseases
Dasiel O. Borroto-Escuela et al.
CELLS (2021)
L-DOPA in Parkinson's Disease: Looking at the False Neurotransmitters and Their Meaning
Abdeslam Chagraoui et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Chemical synthesis, microbial transformation and biological evaluation of tetrahydroprotoberberines as dopamine D1/D2 receptor ligands
Haixia Ge et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2019)
Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure-Functional Selectivity Relationships (SFSRs) and Therapeutic Potential
Liang Tan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
[F-18] fallypride characterization of striatal and extrastriatal D-2/3 receptors in Parkinson's disease
Adam J. Stark et al.
NEUROIMAGE-CLINICAL (2018)
Affinity, potency, efficacy, and selectivity of neurokinin A analogs at human recombinant NK2 and NK1 receptors
Nadia M. J. Rupniak et al.
PLOS ONE (2018)
Multivalent approaches and beyond: novel tools for the investigation of dopamine D2 receptor pharmacology
Anitha Kopinathan et al.
FUTURE MEDICINAL CHEMISTRY (2016)
Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity
Mu-Fa Zou et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Validity of Quinpirole Sensitization Rat Model of OCD: Linking Evidence from Animal and Clinical Studies
Ales Stuchlik et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2016)
Cell-based and virtual fragment screening for adrenergic α2C receptor agonists
Edit Szollosi et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2015)
Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis
Thomas M. Keck et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Blonanserin Ameliorates Phencyclidine-Induced Visual-Recognition Memory Deficits: the Complex Mechanism of Blonanserin Action Involving D3-5-HT2A and DI-NMDA Receptors in the mPFC
Hirotake Hida et al.
NEUROPSYCHOPHARMACOLOGY (2015)
Functionally Selective Dopamine D2, D3 Receptor Partial Agonists
Dorothee Moeller et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Novel Arylsulfonamide Derivatives with 5-HT6/5-HT7 Receptor Antagonism Targeting Behavioral and Psychological Symptoms of Dementia
Marcin Kolaczkowski et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
What is pharmacological 'affinity'? Relevance to biased agonism and antagonism
Terry Kenakin
TRENDS IN PHARMACOLOGICAL SCIENCES (2014)
Local control of striatal dopamine release
Roger Cachope et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2014)
Discovery and Characterization of a G Protein-Biased Agonist That Inhibits β-Arrestin Recruitment to the D2 Dopamine Receptor
R. Benjamin Free et al.
MOLECULAR PHARMACOLOGY (2014)
Discovery of novel α1-adrenoceptor ligands based on the antipsychotic sertindole suitable for labeling as PET ligands
Morten Jorgensen et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Volume transmission and its different forms in the central nervous system
Kjell Fuxe et al.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE (2013)
Profile of blonanserin for the treatment of schizophrenia
Tomomi Tenjin et al.
NEUROPSYCHIATRIC DISEASE AND TREATMENT (2013)
Shape-Based Reprofiling of FDA-Approved Drugs for the H1 Histamine Receptor
Sridhar R. Vasudevan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Identifying mechanism-of-action targets for drugs and probes
Elisabet Gregori-Puigjane et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The synthesis and receptor binding affinities of DDD-016, a novel, potential, atypical antipsychotic
Achintya Bandyopadhyaya et al.
MEDCHEMCOMM (2012)
CNS and antimalarial activity of synthetic meridianin and psammopemmin analogs
Matthew D. Lebar et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2011)
Synthesis and characterization of selective dopamine D2 receptor antagonists. 2. Azaindole, benzofuran, and benzothiophene analogs of L-741,626
Suwanna Vangveravong et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
Novel 7-phenylsulfanyl-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a]indoles as dual serotonin 5-HT2C and 5-HT6 receptor ligands
N. Krogsgaard-Larsen et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Blonanserin A Review of its Use in the Management of Schizophrenia
Emma D. Deeks et al.
CNS DRUGS (2010)
Exploring the Neuroleptic Substituent in Octoclothepin: Potential Ligands for Positron Emission Tomography with Subnanomolar Affinity for α1-Adrenoceptors
Jesper L. Kristensen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Pharmacology of signaling induced by dopamine D-1-like receptor activation
Ashiwel S. Undieh
PHARMACOLOGY & THERAPEUTICS (2010)
Dopaminergic augmentation of delta-9-tetrahydrocannabinol (THC) discrimination: possible involvement of D-2-induced formation of anandamide
Marcello Solinas et al.
PSYCHOPHARMACOLOGY (2010)
'Click' D1 receptor agonists with a 5-HT1A receptor pharmacophore producing D2 receptor activity
Jing Zhang et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Investigation of various N-heterocyclic substituted piperazine versions of 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol: Effect on affinity and selectivity for dopamine D3 receptor
Dennis A. Brown et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Pharmacological comparison of muscarinic ligands: Historical versus more recent muscarinic M1-preferring receptor agonists
Julia N. Heinrich et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Identification of a butyrophenone analog as a potential atypical antipsychotic agent: 4-[4-(4-Chlorophenyl)-1,4-diazepan-1-yl]-1(4-fluorophenyl)butan-1-one
Seth Y. Ablordeppey et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Serotonin receptors
David E. Nichols et al.
CHEMICAL REVIEWS (2008)
Novel D3 Selective Dopaminergics Incorporating Enyne Units as Nonaromatic Catechol Bioisosteres: Synthesis, Bioactivity, and Mutagenesis Studies
Miriam Doerfler et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
In vitro affinities of various halogenated benzamide derivatives as potential radioligands for non-invasive quantification of D2-like dopamine receptors
Daniela Stark et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2007)
Principal component analysis differentiates the receptor binding profiles of three antipsychotic drug candidates from current antipsychotic drugs
Jos H. M. Lange et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Heterocyclic analogues of N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands:: Potential substance abuse therapeutic agents
Peter Grundt et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Analogues of the dopamine D2 receptor antagonist L741,626: Binding, function, and SAR
Peter Grundt et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors:: Identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist
ES Burstein et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Differences between A 68930 and SKF 82958 could suggest synergistic roles of D1 and D5 receptors
R Nergårdh et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2005)
Pharmacophore-guided drug discovery investigations leading to bioactive 5-aminotetrahydropyrazolopyridines.: Implications for the binding mode of heterocyclic dopamine D3 receptor agonists
J Elsner et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Sumanirole, a highly dopamine D2-selective receptor agonist:: In vitro and in vivo pharmacological characterization and efficacy in animal models of Parkinson's disease
RB McCall et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents
AH Newman et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Stable expression of constitutively activated mutant h5HT6 and h5HT7 serotonin receptors:: inverse agonist activity of antipsychotic drugs
A Purohit et al.
PSYCHOPHARMACOLOGY (2005)
Discovery of new tetracyclic tetrahydrofuran derivatives as potential broad-spectrum psychotropic agents
J Fernández et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Syntheses and properties of the major hydroxy metabolites in humans of blonanserin AD-5423, a novel antipsychotic agent
T Ochi et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
Pharmacophore identification of α1A-adrenoceptor antagonists
MY Li et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
The predicted 3D structure of the human D2 dopamine receptor and the binding site and binding affinities for agonists and antagonists
MYS Kalani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Heterodimerization of G-protein-coupled receptors reveals an unexpected level of pharmacological diversity
R Maggio et al.
MEDICINAL CHEMISTRY RESEARCH (2004)
Synthesis and biological activity of 2-carbomethoxy-3-catechol-8-azabicyclo[3.2.1]octanes
PC Meltzer et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2003)
Distinct roles of D1 and D5 dopamine receptors in motor activity and striatal synaptic plasticity
D Centonze et al.
JOURNAL OF NEUROSCIENCE (2003)
Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology
DA Shapiro et al.
NEUROPSYCHOPHARMACOLOGY (2003)
Pharmacological profile of the vascular responses to dopamine in the canine external carotid circulation
CM Villalón et al.
PHARMACOLOGY & TOXICOLOGY (2003)
HI-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs
WK Kroeze et al.
NEUROPSYCHOPHARMACOLOGY (2003)
Synthesis and structure-affinity relationship investigations of 5-heteroaryl-substituted analogues of the antipsychotic sertindole.: A new class of highly selective α1 adrenoceptor antagonists
T Balle et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
Mice lacking D5 dopamine receptors have increased sympathetic tone and are hypertensive
TR Hollon et al.
JOURNAL OF NEUROSCIENCE (2002)
Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. I. A multivariate analysis of the binding profiles of 14 drugs at 21 native and cloned human receptor subtypes
MJ Millan et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Extended radioligand binding profile of iloperidone: A broad spectrum dopamine/serotonin/norepinephrine receptor antagonist for the management of psychotic disorders
HO Kalkman et al.
NEUROPSYCHOPHARMACOLOGY (2001)
Age-related changes of dopamine receptors in the rat hippocampus: a light microscope autoradiography study
F Amenta et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2001)
Differential dependence of the D1 and D5 dopamine receptors on the G protein γ7 subunit for activation of adenylylcyclase
Q Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Affinity of serotonin receptor antagonists and agonists to recombinant and native α1-adrenoceptor subtypes
R Yoshio et al.
JAPANESE JOURNAL OF PHARMACOLOGY (2001)
Current and novel approaches to the drug treatment of schizophrenia
M Rowley et al.
JOURNAL OF MEDICINAL CHEMISTRY (2001)
Antipsychotic drugs, dopamine receptors, and schizophrenia
P Seeman
CLINICAL NEUROSCIENCE RESEARCH (2001)
CoMFA-based prediction of agonist affinities at recombinant wild type versus serine to alanine point mutated D2 dopamine receptors
RE Wilcox et al.
JOURNAL OF MEDICINAL CHEMISTRY (2000)
Syntheses of (R)- and (S)-2- and 6-fluoronorepinephrine and (R)- and (S)-2- and 6-fluoroepinephrine:: Effect of stereochemistry on fluorine-induced adrenergic selectivities
SF Lu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2000)
N-{[1-(2-phenylethyl)pyrrolidin-2-yl]methyl}cyclohexane-carboxamides as selective 5-HT1A receptor agonists
M Fujio et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2000)
Structure and function of dopamine receptors
D Vallone et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2000)