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Behavior of KCNQ Channels in Neural Plasticity and Motor Disorders

MEMBRANES (2022)

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Review Neurosciences

Potassium Channels: A Potential Therapeutic Target for Parkinson's Disease

Xiaoyan Chen et al.

NEUROSCIENCE BULLETIN (2018)

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Article Hematology

Investigating the Role of G Protein in Kv7-Dependent Relaxations of the Rat Vasculature

Jennifer B. Stott et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2018)

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Article Neurosciences

The Kv7/KCNQ channel blocker XE991 protects nigral dopaminergic neurons in the 6-hydroxydopamine rat model of Parkinson's disease

Haixia Liu et al.

BRAIN RESEARCH BULLETIN (2018)

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Article Cardiac & Cardiovascular Systems

Complex aberrant splicing in the induced pluripotent stem cell-derived cardiomyocytes from a patient with long QT syndrome carrying KCNQ1-A344Aspl mutation

Yimin Wuriyanghai et al.

HEART RHYTHM (2018)

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Article Biology

The fate of hippocampal synapses depends on the sequence of plasticity-inducing events

J. Simon Wiegert et al.

ELIFE (2018)

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Article Pharmacology & Pharmacy

The pan-Kv7 (KCNQ) Channel Opener Retigabine Inhibits Striatal Excitability by Direct Action on Striatal Neurons In Vivo

Henrik H. Hansen et al.

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2017)

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Article Neurosciences

Hippocampal formation alterations differently contribute to autobiographic memory deficits in mild cognitive impairment and Alzheimer's disease

Dusan Hirjak et al.

HIPPOCAMPUS (2017)

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Letter Genetics & Heredity

Possible mechanisms for sensorineural hearing loss and deafness in patients with propionic acidemia

S. C. Gruenert et al.

ORPHANET JOURNAL OF RARE DISEASES (2017)

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Editorial Material Oncology

Targeting Kv7 channels in pain pathways

Ivan Rivera-Arconada et al.

ONCOTARGET (2017)

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Article Clinical Neurology

Levodopa-induced Dyskinesia: Clinical Features, Pathophysiology, and Medical Management

Sanjay Pandey et al.

ANNALS OF INDIAN ACADEMY OF NEUROLOGY (2017)

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Review Chemistry, Multidisciplinary

KCNQ potassium channels in sensory system and neural circuits

Jing-jing Wang et al.

ACTA PHARMACOLOGICA SINICA (2016)

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Article Chemistry, Multidisciplinary

Activation of neuronal Kv7/KCNQ/M-channels by the opener QO58-lysine and its anti-nociceptive effects on inflammatory pain in rodents

Bo-chuan Teng et al.

ACTA PHARMACOLOGICA SINICA (2016)

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Article Genetics & Heredity

KCNQ1 Mutations Associated with Jervell and Lange-Nielsen Syndrome and Autosomal Recessive Romano-Ward Syndrome in India-Expanding the Spectrum of Long QT Syndrome Type 1

Bijal Vyas et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2016)

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Article Pharmacology & Pharmacy

Selective activation of vascular Kv7.4/Kv7.5 K+ channels by fasudil contributes to its vasorelaxant effect

Xuan Zhang et al.

BRITISH JOURNAL OF PHARMACOLOGY (2016)

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Article Genetics & Heredity

Mutations in the genes for thyroglobulin and thyroid peroxidase cause thyroid dyshormonogenesis and autosomal-recessive intellectual disability

Kirti Mittal et al.

JOURNAL OF HUMAN GENETICS (2016)

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Article Clinical Neurology

Increasing Neuroplasticity to Bolster Chronic Pain Treatment: A Role for Intermittent Fasting and Glucose Administration?

Kimberly T. Sibille et al.

JOURNAL OF PAIN (2016)

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Article Neurosciences

Effects of novel subtype selective M-current activators on spinal reflexes in vitro: Comparison with retigabine

Jorge Vicente-Baz et al.

NEUROPHARMACOLOGY (2016)

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Article Genetics & Heredity

Variable clinical expression in patients with mosaicism for KCNQ2 mutations

Mathieu Milh et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2015)

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Article Behavioral Sciences

Flupirtine attenuates chronic restraint stress-induced cognitive deficits and hippocampal apoptosis in male mice

Pengcheng Huang et al.

BEHAVIOURAL BRAIN RESEARCH (2015)

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Article Cell & Tissue Engineering

Characterization of a novel KCNQ1 mutation for type 1 long QT syndrome and assessment of the therapeutic potential of a novel IKs activator using patient-specific induced pluripotent stem cell-derived cardiomyocytes

Dongrui Ma et al.

STEM CELL RESEARCH & THERAPY (2015)

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Article Clinical Neurology

DNA methylation and expression of KCNQ3 in bipolar disorder

Zachary Kaminsky et al.

BIPOLAR DISORDERS (2015)

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Review Pharmacology & Pharmacy

New antiepileptic medication linked to blue discoloration of the skin and eyes

Sarah Clark et al.

THERAPEUTIC ADVANCES IN DRUG SAFETY (2015)

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Article Biochemistry & Molecular Biology

Identifying the Subfamilies of Voltage-Gated Potassium Channels Using Feature Selection Technique

Wei-Xin Liu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

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Article Cardiac & Cardiovascular Systems

Prevalence and Potential Genetic Determinants of Sensorineural Deafness in KCNQ1 Homozygosity and Compound Heterozygosity

John R. Giudicessi et al.

CIRCULATION-CARDIOVASCULAR GENETICS (2013)

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Article Behavioral Sciences

Distinct neuroanatomical bases of episodic and semantic memory performance in Alzheimer's disease

Daniela I. Hirni et al.

NEUROPSYCHOLOGIA (2013)

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Article Neurosciences

The KV7.2/3 preferring channel opener ICA 27243 attenuates L-DOPA-induced dyskinesia in hemiparkinsonian rats

Svenja E. Sander et al.

NEUROSCIENCE LETTERS (2013)

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Review Multidisciplinary Sciences

Long-term depression and other synaptic plasticity in the cerebellum

Tomoo Hirano

PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES (2013)

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Article Multidisciplinary Sciences

Long-term depression triggers the selective elimination of weakly integrated synapses

J. Simon Wiegert et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

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Article Multidisciplinary Sciences

Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels

Haibo Yu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

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Article Chemistry, Medicinal

Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective Kv7.1 (KCNQ1) potassium channel activator

Margrith E. Mattmann et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)

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Article Clinical Neurology

Hippocampal Morphology and Autobiographic Memory in Mild Cognitive Impairment and Alzheimer's Disease

Philipp A. Thomann et al.

CURRENT ALZHEIMER RESEARCH (2012)

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Review Clinical Neurology

The mechanism of action of retigabine (ezogabine), a first-in-class K+ channel opener for the treatment of epilepsy

Martin J. Gunthorpe et al.

EPILEPSIA (2012)

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Article Neurosciences

Functional division of hippocampal area CA1 via modulatory gating of entorhinal cortical inputs

Hiroshi T. Ito et al.

HIPPOCAMPUS (2012)

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Article Neurosciences

Retigabine, a KV7 (KCNQ) potassium channel opener, attenuates L-DOPA-induced dyskinesias in 6-OHDA-lesioned rats

S. E. Sander et al.

NEUROPHARMACOLOGY (2012)

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Article Multidisciplinary Sciences

Inhibition of Post-Synaptic Kv7/KCNQ/M Channels Facilitates Long-Term Potentiation in the Hippocampus

Milos M. Petrovic et al.

PLOS ONE (2012)

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Article Cell Biology

KCNQ5/Kv7.5 potassium channel expression and subcellular localization in primate retinal pigment epithelium and neural retina

Xiaoming Zhang et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2011)

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Article Neurosciences

The M-Current Inhibitor XE991 Decreases the Stimulation Threshold for Long-Term Synaptic Plasticity in Healthy Mice and in Models of Cognitive Disease

Angela Fontan-Lozano et al.

HIPPOCAMPUS (2011)

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Article Pharmacology & Pharmacy

Aminoglycosides Inhibit KCNQ4 Channels in Cochlear Outer Hair Cells via Depletion of Phosphatidylinositol(4,5)bisphosphate

Michael G. Leitner et al.

MOLECULAR PHARMACOLOGY (2011)

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Article Medicine, Research & Experimental

A Guide to Neurotoxic Animal Models of Parkinson's Disease

Kim Tieu

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2011)

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Article Pharmacology & Pharmacy

Modulation of drug block of the cardiac potassium channel KCNA5 by the drug transporters OCTN1 and MDR1

Tao Yang et al.

BRITISH JOURNAL OF PHARMACOLOGY (2010)

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Article Multidisciplinary Sciences

The KCNQ5 potassium channel mediates a component of the afterhyperpolarization current in mouse hippocampus

Anastassios V. Tzingounis et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

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Review Pharmacology & Pharmacy

Neural KCNQ (Kv7) channels

David A. Brown et al.

BRITISH JOURNAL OF PHARMACOLOGY (2009)

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Article Neurosciences

Subicular and CA1 Hippocampal Projections to the Accessory Olfactory Bulb

C. de la Rosa-Prieto et al.

HIPPOCAMPUS (2009)

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Article Multidisciplinary Sciences

The Acrylamide (S)-2 As a Positive and Negative Modulator of Kv7 Channels Expressed in Xenopus laevis Oocytes

Sigrid Marie Blom et al.

PLOS ONE (2009)

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Article Clinical Neurology

Developmental changes in KCNQ2 and KCNQ3 expression in human brain: Possible contribution to the age-dependent etiology of benign familial neonatal convulsions

Takeshi Kanaumi et al.

BRAIN & DEVELOPMENT (2008)

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Article Neurosciences

Kv7 channels: interaction with dopaminergic and serotonergic neurotransmission in the CNS

Henrik H. Hansen et al.

JOURNAL OF PHYSIOLOGY-LONDON (2008)

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Article Biochemistry & Molecular Biology

Zinc pyrithione-mediated activation of voltage-gated KCNQ potassium channels rescues epileptogenic mutants

Qiaojie Xiong et al.

NATURE CHEMICAL BIOLOGY (2007)

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Article Neurosciences

M-channels (Kv7/KCNQ channels) that regulate synaptic integration, excitability, and spike pattern of CA1 pyramidal cells are located in the perisomatic region

Hua Hu et al.

JOURNAL OF NEUROSCIENCE (2007)

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Review Neurosciences

The 6-hydroxydopamine model of Parkinson's disease

Nicola Simola et al.

NEUROTOXICITY RESEARCH (2007)

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Article Neurosciences

Coexistence of muscarinic long-term depression with electrically induced long-term potentiation and depression at CA3-CA1 synapses

Eve McCutchen et al.

JOURNAL OF NEUROPHYSIOLOGY (2006)

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Article Neurosciences

The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels

Bo Hjorth Bentzen et al.

NEUROPHARMACOLOGY (2006)

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Review Physiology

The KCNQ1 potassium channel: From gene to physiological function

T Jespersen et al.

PHYSIOLOGY (2005)

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Review Neurosciences

Pathways modulating neural KCNQ/M (Kv7) potassium channels

P Delmas et al.

NATURE REVIEWS NEUROSCIENCE (2005)

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Article Biochemistry & Molecular Biology

Dopaminergic neurons

SJ Chinta et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2005)

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Article Neurosciences

KCNQ2 is a nodal K+ channel

JJ Devaux et al.

JOURNAL OF NEUROSCIENCE (2004)

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Article Neurosciences

Bi-directional plasticity and age-dependent long-term depression at mouse CA3-CA1 hippocampal synapses

AJ Milner et al.

NEUROSCIENCE LETTERS (2004)

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Article Multidisciplinary Sciences

Hippocampal long-term depression and long-term potentiation encode different aspects of novelty acquisition

A Kemp et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

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Article Neurosciences

A-type potassium currents active at subthreshold potentials in mouse cerebellar Purkinje cells

T Sacco et al.

JOURNAL OF PHYSIOLOGY-LONDON (2002)

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Article Pharmacology & Pharmacy

Blockade of human cardiac potassium channel human ether-a-go-go-related gene (HERG) by macrolide antibiotics

WA Volberg et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)

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Article Cardiac & Cardiovascular Systems

Clinical aspects and molecular genetics of the Jervell and Lange-Nielsen syndrome

G Mönnig et al.

ZEITSCHRIFT FUR KARDIOLOGIE (2002)

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Article Neurosciences

M channel KCNQ2 subunits are localized to key sites for control of neuronal network oscillations and synchronization in mouse brain

EC Cooper et al.

JOURNAL OF NEUROSCIENCE (2001)

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Review Pharmacology & Pharmacy

KCNQ potassium channels: physiology, pathophysiology, and pharmacology

J Robbins

PHARMACOLOGY & THERAPEUTICS (2001)

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Review Neurosciences

Neuronal KCNQ potassium channels: Physiology and role in disease

TJ Jentsch

NATURE REVIEWS NEUROSCIENCE (2000)

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Review Genetics & Heredity

Channelopathies: ion channel defects linked to heritable clinical disorders

R Felix

JOURNAL OF MEDICAL GENETICS (2000)

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