相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Phytochemicals from the Cocoa Shell Modulate Mitochondrial Function, Lipid and Glucose Metabolism in Hepatocytes via Activation of FGF21/ERK, AKT, and mTOR Pathways
Miguel Rebollo-Hernanz et al.
ANTIOXIDANTS (2022)
Effect of processing on bioaccessibility and bioavailability - of bioactive compounds in coffee beans
Hanjing Wu et al.
FOOD BIOSCIENCE (2022)
Protocatechuic acid protects hepatocytes against hydrogen peroxide-induced oxidative stress
Wu-Joo Lee et al.
CURRENT RESEARCH IN FOOD SCIENCE (2022)
Obtaining Bioactive Compounds from the Coffee Husk (Coffea arabica L.) Using Different Extraction Methods
Mariana de Oliveira Silva et al.
MOLECULES (2021)
Bupleuri radix extract ameliorates impaired lipid metabolism in high-fat diet-induced obese mice via gut microbia-mediated regulation of FGF21 signaling pathway
Liucen Wu et al.
BIOMEDICINE & PHARMACOTHERAPY (2021)
Evaluation of bioactive compounds, phytochemicals profile and antioxidant potential of the aqueous and ethanolic extracts of some traditional fruit tree leaves used in Brazilian folk medicine
Julianna Karla Santana Andrade et al.
FOOD RESEARCH INTERNATIONAL (2021)
Oxidative Stress in Non-alcoholic Fatty Liver Disease. An Updated Mini Review
Anna Pia Delli Bovi et al.
FRONTIERS IN MEDICINE (2021)
Mechanisms and disease consequences of nonalcoholic fatty liver disease
Rohit Loomba et al.
CELL (2021)
Coffea arabica pulp aqueous extract attenuates oxidative stress and hepatic lipid accumulation in HepG2 cells
Atcharaporn Ontawong et al.
JOURNAL OF HERBAL MEDICINE (2021)
Revalorization of Coffee Husk: Modeling and Optimizing the Green Sustainable Extraction of Phenolic Compounds
Miguel Rebollo-Hernanz et al.
FOODS (2021)
Kaempferol and Kaempferide Attenuate Oleic Acid-Induced Lipid Accumulation and Oxidative Stress in HepG2 Cells
Fangfang Tie et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Aqueous Extract of Pepino Leaves Ameliorates Palmitic Acid-Induced Hepatocellular Lipotoxicity via Inhibition of Endoplasmic Reticulum Stress and Apoptosis
Jen-Ying Hsu et al.
ANTIOXIDANTS (2021)
Biomolecules extraction from coffee and cocoa by- and co-products using deep eutectic solvents
Mariana Ruesgas-Ramon et al.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2020)
β-Klotho gene variation is associated with liver damage in children with NAFLD
Paola Dongiovanni et al.
JOURNAL OF HEPATOLOGY (2020)
Caffeine, but not other phytochemicals, in mate tea (Ilex paraguariensis St. Hilaire) attenuates high-fat-high-sucrose-diet-driven lipogenesis and body fat accumulation
Fatima J. Zapata et al.
JOURNAL OF FUNCTIONAL FOODS (2020)
Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non-alcoholic fatty liver disease by up-regulating the FGF21/PGC-1α pathway
Liwei Wu et al.
BRITISH JOURNAL OF PHARMACOLOGY (2020)
Dietary Cyanidin-3-Glucoside Attenuates High-Fat-Diet-Induced Body-Weight Gain and Impairment of Glucose Tolerance in Mice via Effects on the Hepatic Hormone FGF21
Lili Tian et al.
JOURNAL OF NUTRITION (2020)
Adipogenic commitment induced by green tea polyphenols remodel adipocytes to a thermogenic phenotype
Anaysa Paola Bolin et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2020)
FGF21 Mimics a Fasting-Induced Metabolic State and Increases Appetite in Zebrafish
Ayelen Melisa Blanco et al.
SCIENTIFIC REPORTS (2020)
Non-esterified Fatty Acid Induce Dairy Cow Hepatocytes Apoptosis via the Mitochondria-Mediated ROS-JNK/ERK Signaling Pathway
Yu Li et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Sirtuin 3-mediated deacetylation of acyl-CoAsynthetase family member 3 by protocatechuic acid attenuates non-alcoholic fatty liver disease
Ruimin Sun et al.
BRITISH JOURNAL OF PHARMACOLOGY (2020)
Targeting the MAPK/ERK and PI3K/AKT Signaling Pathways Affects NRF2, Trx and GSH Antioxidant Systems in Leukemia Cells
Ewa Jasek-Gajda et al.
ANTIOXIDANTS (2020)
Protocatechuic acid attenuates adipogenesis-induced inflammation and mitochondrial dysfunction in 3T3-L1 adipocytes by regulation of AMPK pathway
Qiaozhi Zhang et al.
JOURNAL OF FUNCTIONAL FOODS (2020)
Understanding lipotoxicity in NAFLD pathogenesis: is CD36 a key driver?
Patricia Rada et al.
CELL DEATH & DISEASE (2020)
FGF21: An Emerging Therapeutic Target for Non-Alcoholic Steatohepatitis and Related Metabolic Diseases
Erik J. Tillman et al.
FRONTIERS IN ENDOCRINOLOGY (2020)
Mangiferin Improved Palmitate-Induced-Insulin Resistance by Promoting Free Fatty Acid Metabolism in HepG2 and C2C12 Cells via PPAR: Mangiferin Improved Insulin Resistance
Qiao Zhang et al.
JOURNAL OF DIABETES RESEARCH (2019)
Liver-derived fibroblast growth factor 21 mediates effects of glucagon-like peptide-1 in attenuating hepatic glucose output
Junling Liu et al.
EBIOMEDICINE (2019)
Cocoa Shell Aqueous Phenolic Extract Preserves Mitochondrial Function and Insulin Sensitivity by Attenuating Inflammation between Macrophages and Adipocytes In Vitro
Miguel Rebollo-Hernanz et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2019)
FGF21 as Modulator of Metabolism in Health and Disease
Caterina Tezze et al.
FRONTIERS IN PHYSIOLOGY (2019)
Binding affinity in drug design: experimental and computational techniques
Visvaldas Kairys et al.
EXPERT OPINION ON DRUG DISCOVERY (2019)
Chlorogenic acid promotes the Nrf2/HO-1 anti-oxidative pathway by activating p21Waf1/Cip1 to resist dexamethasone-induced apoptosis in osteoblastic cells
Dandan Han et al.
FREE RADICAL BIOLOGY AND MEDICINE (2019)
Attenuation of Palmitic Acid-Induced Lipotoxicity by Chlorogenic Acid through Activation of SIRT1 in Hepatocytes
Lele Yang et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2019)
Ginsenoside Rg1 Ameliorates Palmitic Acid-Induced Hepatic Steatosis and Inflammation in HepG2 Cells via the AMPK/NF-κB Pathway
Qing Xiao et al.
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (2019)
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
Yingyao Zhou et al.
NATURE COMMUNICATIONS (2019)
Fibroblast Growth Factor 21 and the Adaptive Response to Nutritional Challenges
Ursula Martinez-Garza et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Phenolic compounds from coffee by-products modulate adipogenesis-related inflammation, mitochondrial dysfunction, and insulin resistance in adipocytes, via insulin/PI3K/AKT signaling pathways
Miguel Rebollo-Hernanz et al.
FOOD AND CHEMICAL TOXICOLOGY (2019)
Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies
Norbert Stefan et al.
LANCET DIABETES & ENDOCRINOLOGY (2019)
Maresin 1 Regulates Hepatic FGF21 in Diet-Induced Obese Mice and in Cultured Hepatocytes
L. Martinez-Fernandez et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2019)
Coffee Silverskin Extract: Nutritional Value, Safety and Effect on Key Biological Functions
Amaia Iriondo-DeHond et al.
NUTRIENTS (2019)
Protocatechuic acid exhibits hepatoprotective, vasculoprotective, antioxidant and insulin-like effects in dexamethasone-induced insulin-resistant rats
Yomna A. El-Sonbaty et al.
BIOCHIMIE (2019)
Response surface methodology to optimise the heat-assisted aqueous extraction of phenolic compounds from coffee parchment and their comprehensive analysis
Yolanda Aguilera et al.
FOOD & FUNCTION (2019)
Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention
Zobair Younossi et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2018)
Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease
David Hojland Ipsen et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Chemical composition and value-adding applications of coffee industry by-products: A review
Brendan Janissen et al.
RESOURCES CONSERVATION AND RECYCLING (2018)
Food based dietary patterns and chronic disease prevention
Matthias B. Schulze et al.
BMJ-BRITISH MEDICAL JOURNAL (2018)
Food based dietary patterns and chronic disease prevention
Matthias B. Schulze et al.
BMJ-BRITISH MEDICAL JOURNAL (2018)
AMPK Activation Reduces Hepatic Lipid Content by Increasing Fat Oxidation In Vivo
Marc Foretz et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Agonistic β-Klotho antibody mimics fibroblast growth factor 21 (FGF21) functions
Xiaoshan Min et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Structures of β-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling
Sangwon Lee et al.
NATURE (2018)
Diet Polyphenol Curcumin Stimulates Hepatic Fgf21 Production and Restores Its Sensitivity in High-Fat-Diet-Fed Male Mice
Kejing Zeng et al.
ENDOCRINOLOGY (2017)
The hepatokine FGF21 is crucial for peroxisome proliferator-activated receptor-α agonist-induced amelioration of metabolic disorders in obese mice
Tsuyoshi Goto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
N-3 polyunsaturated fatty acids increase hepatic fibroblast growth factor 21 sensitivity via a PPAR-γ-β-klotho pathway
Wenqi Yang et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2017)
Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis
Anna M. Diehl et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Fibroblast growth factor 21: a regulator of metabolic disease and health span
Ting Xie et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2017)
FGF21-receptor agonists: an emerging therapeutic class for obesity-related diseases
Junichiro Sonoda et al.
HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION (2017)
Treatment of nonalcoholic fatty liver disease: role of AMPK
Brennan K. Smith et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2016)
Chlorogenic acid ameliorates endotoxin-induced liver injury by promoting mitochondrial oxidative phosphorylation
Yan Zhou et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
PRODIGY: a web server for predicting the binding affinity of protein-protein complexes
Li C. Xue et al.
BIOINFORMATICS (2016)
Biomechanism of chlorogenic acid complex mediated plasma free fatty acid metabolism in rat liver
H. V. Sudeep et al.
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2016)
Dietary Betaine Supplementation Increases Fgf21 Levels to Improve Glucose Homeostasis and Reduce Hepatic Lipid Accumulation in Mice
Asma Ejaz et al.
DIABETES (2016)
Insights into the Role and Interdependence of Oxidative Stress and Inflammation in Liver Diseases
Sha Li et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
Insights on the health benefits of the bioactive compounds of coffee silverskin extract
Beatriz Fernandez-Gomez et al.
JOURNAL OF FUNCTIONAL FOODS (2016)
NADPH oxidase is implicated in the pathogenesis of oxidative phosphorylation dysfunction in mice fed a high-fat diet
Inmaculada Garcia-Ruiz et al.
SCIENTIFIC REPORTS (2016)
mTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in Adipocytes
Annabel Y. Minard et al.
CELL REPORTS (2016)
Fibroblast Growth Factor Signaling in Metabolic Regulation
Vera J. M. Nies et al.
FRONTIERS IN ENDOCRINOLOGY (2016)
In vivo anti-diabetic potential of chlorogenic acid as a consequence of synergism with other phenolic compounds?
Salvatore Chirumbolo
BRITISH JOURNAL OF NUTRITION (2015)
Free Fatty Acids Impair FGF21 Action in HepG2 Cells
Mohamed Asrih et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2015)
NAFLD: A multisystem disease
Christopher D. Byrne et al.
JOURNAL OF HEPATOLOGY (2015)
Mind the gapdeficits in our knowledge of aspects impacting the bioavailability of phytochemicals and their metabolitesa position paper focusing on carotenoids and polyphenols
Torsten Bohn et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2015)
Protocatechuic acid activates key components of insulin signaling pathway mimicking insulin activity
Beatrice Scazzocchio et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2015)
The modulating effect of Persea americana fruit extract on the level of expression of fatty acid synthase complex, lipoprotein lipase, fibroblast growth factor-21 and leptin - A biochemical study in rats subjected to experimental hyperlipidemia and obesity
Padmanabhan Monika et al.
PHYTOMEDICINE (2015)
In vitro treatment of HepG2 cells with saturated fatty acids reproduces mitochondrial dysfunction found in nonalcoholic steatohepatitis
Inmaculada Garcia-Ruiz et al.
DISEASE MODELS & MECHANISMS (2015)
Cocoa flavonoids attenuate high glucose-induced insulin signalling blockade and modulate glucose uptake and production in human HepG2 cells
Isabel Cordero-Herrera et al.
FOOD AND CHEMICAL TOXICOLOGY (2014)
Anti-diabetic and anti-lipidemic effects of chlorogenic acid are mediated by ampk activation
Khang Wei Ong et al.
BIOCHEMICAL PHARMACOLOGY (2013)
Mitochondrial Adaptations and Dysfunctions in Nonalcoholic Fatty Liver Disease
Karima Begriche et al.
HEPATOLOGY (2013)
Resveratrol Induces a Mitochondrial Complex I-dependent Increase in NADH Oxidation Responsible for Sirtuin Activation in Liver Cells
Valerie Desquiret-Dumas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Bitter melon extract attenuating hepatic steatosis may be mediated by FGF21 and AMPK/Sirt1 signaling in mice
Yongmei Yu et al.
SCIENTIFIC REPORTS (2013)
Hepatic mTORC2 Activates Glycolysis and Lipogenesis through Akt, Glucokinase, and SREBP1c
Asami Hagiwara et al.
CELL METABOLISM (2012)
Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State
Ffolliott M. Fisher et al.
DIABETES (2010)
Neuroprotective effects of arachidonic acid against oxidative stress on rat hippocampal slices
Ze-Jian Wang et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2006)
Raw material enzymatic activity determination: A specific case for validation and comparison of analytical methods - The example of superoxide dismutase (SOD)
JY Zhou et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2006)
Source of early reactive oxygen species in the apoptosis induced by transforming growth factor-beta in fetal rat hepatocytes
B Herrera et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)