4.6 Review

Principles of Virtual Crossmatch Testing for Kidney Transplantation

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Trends and impact on cold ischemia time and clinical outcomes using virtual crossmatch for deceased donor kidney transplantation in the United States

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Summary: Virtual crossmatch is a promising strategy for assessing HLA compatibility in deceased donor kidney transplantation, with the potential to reduce cold ischemia time and optimize transplant outcomes. It shows significant variation in use among transplant regions, but overall, it is associated with shorter cold ischemia times and similar graft loss and mortality compared to physical crossmatch.

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