期刊
JOURNAL OF CELL BIOLOGY
卷 214, 期 7, 页码 793-795出版社
ROCKEFELLER UNIV PRESS
DOI: 10.1083/jcb.201609038
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资金
- Fundacao para a Ciencia e a Tecnologia [IF/00412/2012, EXPL/BEX-BCM/2258/2013]
- Portugal program [LISBOA-01-0145-FEDER-00739]
- European Research Council [679368, 311719]
- Fundação para a Ciência e a Tecnologia [EXPL/BEX-BCM/2258/2013] Funding Source: FCT
- European Research Council (ERC) [679368] Funding Source: European Research Council (ERC)
Bone morphogenic proteins (BMPs) and blood flow regulate vascular remodeling and homeostasis. In this issue, Baeyens et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201603106) show that blood flow sensitizes endothelial cells to BMP9 signaling by triggering Alkl/ENG complexing to suppress cell proliferation and to recruit mural cells, thereby establishing endothelial quiescence.
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