期刊
JOURNAL OF CELL BIOLOGY
卷 215, 期 3, 页码 297-299出版社
ROCKEFELLER UNIV PRESS
DOI: 10.1083/jcb.201610044
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- MRC [MC_U120085810] Funding Source: UKRI
- Medical Research Council [MC_U120085810] Funding Source: Medline
- Medical Research Council [MC_U120085810] Funding Source: researchfish
The senescence-associated secretory phenotype (SASP) is a hallmark of senescence with an important physiological impact, but how it is established is unclear. In this issue, Aird et al. (2016. J. Cell Biol. https://doi.org/10.1083/jcb.201608026) describe how chromatin-bound HMGB2 fine tunes SASP expression by avoiding heterochromatin spreading.
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