相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The orphan GPCR, Gpr161, regulates the retinoic acid and canonical Wnt pathways during neurulation
Bo I. Li et al.
DEVELOPMENTAL BIOLOGY (2015)
Modulation of Ciliary Phosphoinositide Content Regulates Trafficking and Sonic Hedgehog Signaling Output
Marcelo Chavez et al.
DEVELOPMENTAL CELL (2015)
Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling
Francesc R. Garcia-Gonzalo et al.
DEVELOPMENTAL CELL (2015)
Crosstalk between Akt/GSK3β signaling and dynamin-1 regulates clathrin-mediated endocytosis
Carlos R. Reis et al.
EMBO JOURNAL (2015)
Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5
Yong Chun Chong et al.
GENES & DEVELOPMENT (2015)
Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation
Quanlong Lu et al.
NATURE CELL BIOLOGY (2015)
Identification of G Protein-Coupled Receptors (GPCRs) in Primary Cilia and Their Possible Involvement in Body Weight Control
Yoshihiro Omori et al.
PLOS ONE (2015)
EFCAB7 and IQCE Regulate Hedgehog Signaling by Tethering the EVC-EVC2 Complex to the Base of Primary Cilia
Ganesh V. Pusapati et al.
DEVELOPMENTAL CELL (2014)
Subcellular optogenetic inhibition of G proteins generates signaling gradients and cell migration
Patrick R. O'Neill et al.
MOLECULAR BIOLOGY OF THE CELL (2014)
Visualization of arrestin recruitment by a G-protein-coupled receptor
Arun K. Shukla et al.
NATURE (2014)
Clathrin regenerates synaptic vesicles from endosomes
Shigeki Watanabe et al.
NATURE (2014)
Simultaneous Measurement of Smoothened Entry Into and Exit From the Primary Cilium
Jynho Kim et al.
PLOS ONE (2014)
G-protein-coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion
Michael E. Feigin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Primary cilia enhance kisspeptin receptor signaling on gonadotropin-releasing hormone neurons
Andrew I. Koemeter-Cox et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
Ophir Shalem et al.
SCIENCE (2014)
Targeting of Smoothened for therapeutic gain
Martial Ruat et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2014)
Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception
Shen Yue et al.
ELIFE (2014)
Structural and Functional Analysis of G Protein-Coupled Receptor Kinase Inhibition by Paroxetine and a Rationally Designed Analog
Kristoff T. Homan et al.
MOLECULAR PHARMACOLOGY (2014)
The Ciliary G-Protein-Coupled Receptor Gpr161 Negatively Regulates the Sonic Hedgehog Pathway via cAMP Signaling
Saikat Mukhopadhyay et al.
CELL (2013)
Divergent β-Arrestin-dependent Signaling Events Are Dependent upon Sequences within G-protein-coupled Receptor C Termini
Kasturi Pal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
GPR88 Reveals a Discrete Function of Primary Cilia as Selective Insulators of GPCR Cross-Talk
Aaron Marley et al.
PLOS ONE (2013)
Neuropeptide Y Family Receptors Traffic via the Bardet-Biedl Syndrome Pathway to Signal in Neuronal Primary Cilia
Alexander V. Loktev et al.
CELL REPORTS (2013)
Paroxetine Is a Direct Inhibitor of G Protein-Coupled Receptor Kinase 2 and Increases Myocardial Contractility
David M. Thal et al.
ACS CHEMICAL BIOLOGY (2012)
Endocytosis of G Protein-Coupled Receptors Is Regulated by Clathrin Light Chain Phosphorylation
Filipe Ferreira et al.
CURRENT BIOLOGY (2012)
A Smoothened-Evc2 Complex Transduces the Hedgehog Signal at Primary Cilia
Karolin V. Dorn et al.
DEVELOPMENTAL CELL (2012)
The base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalization
Jeremy F. Reiter et al.
EMBO REPORTS (2012)
A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain
Ben Chih et al.
NATURE CELL BIOLOGY (2012)
A hierarchy of signals regulates entry of membrane proteins into the ciliary membrane domain in epithelial cells
Stephen S. Francis et al.
JOURNAL OF CELL BIOLOGY (2011)
Clathrin phosphorylation is required for actin recruitment at sites of bacterial adhesion and internalization
Matteo Bonazzi et al.
JOURNAL OF CELL BIOLOGY (2011)
A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition
Francesc R. Garcia-Gonzalo et al.
NATURE GENETICS (2011)
Sonic Hedgehog Dependent Phosphorylation by CK1α and GRK2 Is Required for Ciliary Accumulation and Activation of Smoothened
Yongbin Chen et al.
PLOS BIOLOGY (2011)
An improved bimolecular fluorescence complementation assay with a high signal-to-noise ratio
Yutaka Kodama et al.
BIOTECHNIQUES (2010)
The ciliary membrane
Rajat Rohatgi et al.
CURRENT OPINION IN CELL BIOLOGY (2010)
The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins
Eric W. Humke et al.
GENES & DEVELOPMENT (2010)
TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia
Saikat Mukhopadhyay et al.
GENES & DEVELOPMENT (2010)
A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes
Hanna Tukachinsky et al.
JOURNAL OF CELL BIOLOGY (2010)
Cargo- and adaptor-specific mechanisms regulate clathrin-mediated endocytosis
Marcel Mettlen et al.
JOURNAL OF CELL BIOLOGY (2010)
The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia
Anahi Molla-Herman et al.
JOURNAL OF CELL SCIENCE (2010)
Kinetics of Hedgehog-Dependent Full-Length Gli3 Accumulation in Primary Cilia and Subsequent Degradation
Xiaohui Wen et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
The primary cilium: a signalling centre during vertebrate development
Sarah C. Goetz et al.
NATURE REVIEWS GENETICS (2010)
DISC1 Regulates Primary Cilia That Display Specific Dopamine Receptors
Aaron Marley et al.
PLOS ONE (2010)
A Septin Diffusion Barrier at the Base of the Primary Cilium Maintains Ciliary Membrane Protein Distribution
Qicong Hu et al.
SCIENCE (2010)
Mechanisms of Endocytosis
Gary J. Doherty et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
Miao-Hsueh Chen et al.
GENES & DEVELOPMENT (2009)
Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium
Ljiljana Milenkovic et al.
JOURNAL OF CELL BIOLOGY (2009)
Smoothened Adopts Multiple Active and Inactive Conformations Capable of Trafficking to the Primary Cilium
Christopher W. Wilson et al.
PLOS ONE (2009)
Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus
Jynho Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Hedgehog signal transduction by Smoothened: Pharmacologic evidence for a 2-step activation process
Rajat Rohatgi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
High-throughput generation of tagged stable cell lines for proteomic analysis
Jorge Z. Torres et al.
PROTEOMICS (2009)
G protein-coupled receptor sorting to endosomes and lysosomes
Adriano Marchese et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2008)
Intraflagellar Transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts
Polloneal Jymmiel R. Ocbina et al.
DEVELOPMENTAL DYNAMICS (2008)
Smoothened Signaling in Vertebrates Is Facilitated by a G Protein-coupled Receptor Kinase
Melanie Philipp et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Identification of ciliary localization sequences within the third intracellular loop of G protein-coupled receptors
Nicolas F. Berbari et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
G protein Gαi functions immediately downstream of Smoothened in Hedgehog signalling
Stacey K. Ogden et al.
NATURE (2008)
The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development
Paul G. Matteson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia
Nicolas F. Berbari et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
β-arrestin-mediated localization of smoothened to the primary cilium
Jeffrey J. Kovacs et al.
SCIENCE (2008)
Patched1 regulates Hedgehog signaling at the primary cilium
Rajat Rohatgi et al.
SCIENCE (2007)
A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis
Maxence V. Nachury et al.
CELL (2007)
Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway
Lily I. Jiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
FAPP2, cilium formation, and compartmentalization of the apical membrane in polarized Madin-Darby canine kidney (MDCK) cells
Otilia V. Vieira et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Smoothened signal transduction is promoted by G protein-coupled receptor kinase 2
Alison R. Meloni et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Position-specific chemical modification of siRNAs reduces off-target'' transcript silencing
Aimee L. Jackson et al.
RNA (2006)
Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET)
KDG Pfleger et al.
NATURE METHODS (2006)
Genetic elimination of suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway
J Svärd et al.
DEVELOPMENTAL CELL (2006)
The structural basis of arrestin-mediated regulation of G-protein-coupled receptors
Vsevolod V. Gurevich et al.
PHARMACOLOGY & THERAPEUTICS (2006)
Vertebrate Smoothened functions at the primary cilium
KC Corbit et al.
NATURE (2005)
Activity-dependent internalization of smoothened mediated by β-arrestin 2 and GRK2
W Chen et al.
SCIENCE (2004)
Modulation of Rac localization and function by dynamin
G Schlunck et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
A novel endocytic recycling signal that distinguishes the membrane trafficking of naturally occurring opioid receptors
M Tanowitz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Opinion - Coat proteins: shaping membrane transport
JS Bonifacino et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity
M Persson et al.
GENES & DEVELOPMENT (2002)
Enhanced potency of human sonic hedgehog by hydrophobic modification
FR Taylor et al.
BIOCHEMISTRY (2001)
分享论文
