期刊
FRONTIERS IN CARDIOVASCULAR MEDICINE
卷 9, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fcvm.2022.840929
关键词
COVID-19; vaccine; cardiovascular; complication; mRNA
资金
- Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease of Sichuan Province [xtcx2019-20]
- Key Laboratory of Medical Electrophysiology of Ministry of Education [KeyME-2018-04]
- Open Program of Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province [HYX19007]
- Doctoral Research Initiating Program of Affiliated Hospital of Southwest Medical University [19041]
Vaccination against COVID-19 has become crucial in controlling the pandemic, but it comes with potential cardiovascular complications such as myocarditis and immune thrombocytopenia. Accurate reporting and monitoring of vaccine safety are essential to address public concerns and ensure effective vaccine administration.
Coronavirus disease 2019 (COVID-19) has become a global public health catastrophe. Vaccination against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is proven to be the most effective measure to suppress the pandemic. With the widespread application of the four vaccines, namely, ChAdOx1, Ad26.COV2.S, BNT162b2, and mRNA-1273.2, several adverse effects have been reported. The most serious type of complication is cardiovascularly related, including myocarditis, immune thrombocytopenia (ITP), cerebral sinus venous thrombosis, among others. All these adverse events undermine the health of the vaccinees and affect the administration of the vaccines. As the distribution of COVID-19 vaccines is surrounded by suspicion and rumors, it is essential to provide the public with accurate reports from trusted experts and journals. Monitoring the safety of COVID-19 vaccines is an important and ongoing process that is also urgent. Thus, we summarized the cardiovascular complications of the major types of COVID-19 vaccines, including mRNA vaccines, which are now generally considered to be innovative vaccines, and the future for vaccination against COVID-19, in addition to the underlying pathogenesis and potential therapeutics.
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