4.6 Review

Primary Aldosteronism and Ischemic Heart Disease

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Review Peripheral Vascular Disease

Left ventricular remodeling and dysfunction in primary aldosteronism

Cheng-Hsuan Tsai et al.

Summary: Primary aldosteronism (PA) is a common cause of secondary hypertension and is associated with worse cardiovascular outcomes. Studies have shown that patients with PA have more severe LV remodeling, which may lead to cardiac dysfunction and other complications.

JOURNAL OF HUMAN HYPERTENSION (2021)

Review Endocrinology & Metabolism

Composite Cardiovascular Outcomes in Patients With Primary Aldosteronism Undergoing Medical Versus Surgical Treatment: A Meta-Analysis

Wei-Chieh Huang et al.

Summary: Meta-analyses confirmed the superior performance of surgical treatment over medical treatment in terms of lower incidences of composite cardiovascular outcomes and non-cure of hypertension among patients with primary aldosteronism (PA). Therefore, adrenalectomy can now be concluded as the treatment of choice for lateralized PA.

FRONTIERS IN ENDOCRINOLOGY (2021)

Review Peripheral Vascular Disease

Primary aldosteronism is a public health issue: challenges and opportunities

Renata Libianto et al.

JOURNAL OF HUMAN HYPERTENSION (2020)

Article Endocrinology & Metabolism

Impaired Glucose Metabolism in Primary Aldosteronism Is Associated With Cortisol Cosecretion

Judith Gerards et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2019)

Article Cardiac & Cardiovascular Systems

Mortality From Ischemic Heart Disease Analysis of Data From the World Health Organization and Coronary Artery Disease Risk Factors From NCD Risk Factor Collaboration

Alexandra N. Nowbar et al.

CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES (2019)

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Endothelial Dysfunction in Primary Aldosteronism

Zheng-Wei Chen et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Editorial Material Cardiac & Cardiovascular Systems

The Global Burden of Cardiovascular Diseases and Risk Factors 2020 and Beyond

George A. Mensah et al.

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Left ventricular dysfunction causing ischemia in patients with patent coronary arteries

Thach Nguyen et al.

PERFUSION-UK (2018)

Article Peripheral Vascular Disease

Renal Outcomes in Medically and Surgically Treated Primary Aldosteronism

Gregory L. Hundemer et al.

HYPERTENSION (2018)

Article Endocrinology & Metabolism

Cardiometabolic outcomes and mortality in medically treated primary aldosteronism: a retrospective cohort study

Gregory L. Hundemer et al.

LANCET DIABETES & ENDOCRINOLOGY (2018)

Article Endocrinology & Metabolism

Cortisol Excess in Patients With Primary Aldosteronism Impacts Left Ventricular Hypertrophy

Christian Adolf et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2018)

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Obesity as a Key Factor Underlying Idiopathic Hyperaldosteronism

Youichi Ohno et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2018)

Review Peripheral Vascular Disease

Vascular Consequences of Aldosterone Excess and Mineralocorticoid Receptor Antagonism

Sophocles Chrissobolis

CURRENT HYPERTENSION REVIEWS (2017)

Article Cardiac & Cardiovascular Systems

Early Aldosterone Blockade in Acute Myocardial Infarction The ALBATROSS Randomized Clinical Trial

Farzin Beygui et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2016)

Article Cardiac & Cardiovascular Systems

Cost-Effectiveness of Screening for Primary Aldosteronism and Subtype Diagnosis in the Resistant Hypertensive Patients

Carrie C. Lubitz et al.

CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES (2015)

Article Cardiac & Cardiovascular Systems

Cost-Effectiveness of Screening for Primary Aldosteronism and Subtype Diagnosis in the Resistant Hypertensive Patients

Carrie C. Lubitz et al.

CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES (2015)

Article Cardiac & Cardiovascular Systems

Prognostic role of aldosterone in patients with acute coronary syndrome: short and medium term follow-up

Antonino Mignano et al.

JOURNAL OF CARDIOVASCULAR MEDICINE (2014)

Article Biochemistry & Molecular Biology

Effects of aldosterone on insulin sensitivity and secretion

James M. Luther

STEROIDS (2014)

Article Medicine, General & Internal

Changes in the clinical manifestations of primary aldosteronism

Sun Hwa Kim et al.

KOREAN JOURNAL OF INTERNAL MEDICINE (2014)

Article Peripheral Vascular Disease

Aldosterone and the Risk of Hypertension

Vanessa Xanthakis et al.

CURRENT HYPERTENSION REPORTS (2013)

Article Endocrinology & Metabolism

Long-Term Cardio- and Cerebrovascular Events in Patients With Primary Aldosteronism

Paolo Mulatero et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)

Article Peripheral Vascular Disease

Observational Study Mortality in Treated Primary Aldosteronism The German Conn's Registry

Martin Reincke et al.

HYPERTENSION (2012)

Article Cardiac & Cardiovascular Systems

A role for cardiotrophin-1 in myocardial remodeling induced by aldosterone

Natalia Lopez-Andres et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)

Article Endocrinology & Metabolism

Cardiovascular and Cerebrovascular Comorbidities of Hypokalemic and Normokalemic Primary Aldosteronism: Results of the German Conn's Registry

E. Born-Frontsberg et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)

Article Medicine, General & Internal

Cardiovascular outcomes in patients with primary aldosteronism after treatment

Cristiana Catena et al.

ARCHIVES OF INTERNAL MEDICINE (2008)

Article Cardiac & Cardiovascular Systems

Cardiovascular effects of aldosterone and post-acute myocardial infarction pathophysiology

JN Cohn et al.

AMERICAN JOURNAL OF CARDIOLOGY (2006)

Article Endocrinology & Metabolism

Prevalence and characteristics of the metabolic syndrome in primary aldosteronism

F Fallo et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2006)

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Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism

P Milliez et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2005)

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Serum aldosterone and the incidence of hypertension in nonhypertensive persons

RS Vasan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)

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Aldosterone directly stimulates cardiac myocyte hypertrophy

MP Okoshi et al.

JOURNAL OF CARDIAC FAILURE (2004)