☆ 4.6 Article

C677T Gene Polymorphism of MTHFR Is a Risk Factor for Impaired Renal Function in Pregnant Women With Preeclampsia in the Chinese Han Population

FRONTIERS IN CARDIOVASCULAR MEDICINE (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Developmental Biology

Associations between AGT, MTHFR, and VEGF gene polymorphisms and preeclampsia in the Chinese population

Guifeng Ding et al.

Summary: This study investigated the associations between angiotensinogen, methylenetetrahydrofolate reductase, vascular endothelial growth factor gene polymorphisms, and preeclampsia in the Han Chinese population. The results suggest that a specific variant in the MTHFR gene may increase the risk of preeclampsia in pregnant women, while polymorphisms in the AGT and VEGF genes may not play a significant role in the development of preeclampsia.

PLACENTA (2022)

添加到收藏夹

Article Obstetrics & Gynecology

Associations between Maternal Lipid Profiles and Pregnancy Complications: A Prospective Population-Based Study

Yiqi Zhang et al.

Summary: The study found that maternal lipid profiles throughout pregnancy are significantly associated with GDM, HDCP, and ICP. Combining lipid profiles in the first trimester with other common predictors can effectively improve the predictive power for GDM and HDCP.

AMERICAN JOURNAL OF PERINATOLOGY (2021)

添加到收藏夹

Article Genetics & Heredity

MTHFR (methylenetetrahydrofolate reductase: EC 1.5.1.20) SNPs (single-nucleotide polymorphisms) and homocysteine in patients referred for investigation of fertility

Yves Menezo et al.

Summary: Research shows that MTHFR gene polymorphisms can increase homocysteine levels and impact the fertility of patients with infertility; the C677T genotype has the greatest effect on homocysteine levels, and men and women have different responses to MTHFR gene polymorphisms.

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS (2021)

添加到收藏夹

Article Multidisciplinary Sciences

The methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism is associated with breast cancer subtype susceptibility in southwestern China

Zhen Li et al.

Summary: The MTHFR C677T polymorphism is significantly associated with susceptibility to breast cancer subtypes, with increased risk for TNBC and protective effect for luminal A. Individuals with hypertension have a higher risk for BC, especially TNBC.

PLOS ONE (2021)

添加到收藏夹

Article Cell Biology

Homocysteine Causes Endothelial Dysfunction via Inflammatory Factor-Mediated Activation of Epithelial Sodium Channel (ENaC)

Chen Liang et al.

Summary: This study demonstrated that HHcy activates endothelial ENaC through a ROS/COX-2-dependent SGK-1/Nedd4-2 signaling pathway, leading to endothelial dysfunction. The findings suggest that blocking endothelial ENaC could be a potential strategy for preventing and treating HHcy-induced cardiovascular disease.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Persistent Hypertension Up to One Year Postpartum among Women with Hypertensive Disorders in Pregnancy in a Low-Resource Setting: A Prospective Cohort Study

Salisu M. Ishaku et al.

Summary: A study conducted in Nigeria found that a significant proportion of women with hypertensive disorders in pregnancy continue to have persistent hypertension one year postpartum, with age and body mass index identified as significant risk factors for persistent hypertension.

GLOBAL HEART (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

C677T MTHFR Gene Polymorphism is Contributing Factor in Development of Renal Impairment in Young Hypertensive Patients

Hanaa H. Elsaid et al.

Summary: The study investigated the relationship between MTHFR gene polymorphism, homocysteine concentrations, and renal impairment in young hypertensive patients. It found that individuals with the TT genotype had higher levels of homocysteine and urinary albumin creatinine ratio, and those carrying the T allele were at a higher risk for hypertension and early renal impairment. The findings suggest that genetic variants of MTHFR gene and hyperhomocysteinemia may contribute to the rapid progression of renal impairment in young hypertensive patients.

INDIAN JOURNAL OF CLINICAL BIOCHEMISTRY (2021)

添加到收藏夹

Article Endocrinology & Metabolism

Association of methylenetetrahydrofolate reductase C677T polymorphism with the pre-eclampsia risk in Hakka pregnant women in Southern China

Jingyuan Hou et al.

GYNECOLOGICAL ENDOCRINOLOGY (2020)

添加到收藏夹

Article Obstetrics & Gynecology

Serum calcium-magnesium ratio in women with pre-eclampsia at a tertiary hospital in Nigeria

Collins E. M. Okoror et al.

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

Methylenetetrahydrofolate reductase polymorphism in healthy volunteers and its correlation with homocysteine levels in patients with thrombosis

Renuka Munshi et al.

INDIAN JOURNAL OF PHARMACOLOGY (2019)

添加到收藏夹

Article Hematology

Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T) as a Risk Factor for Arterial Thrombosis in Georgian Patients

Sopio Garakanidze et al.

CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Diet-induced hyperhomocysteinemia impairs vasodilation in 5/6-nephrectomized rats

Lei Li et al.

AMINO ACIDS (2018)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Independent and Joint Association of Blood Pressure, Serum Total Homocysteine, and Fasting Serum Glucose Levels With Brachial-Ankle Pulse Wave Velocity in Chinese Hypertensive Adults

Xiaoyun Liu et al.

INTERNATIONAL HEART JOURNAL (2016)

添加到收藏夹

Article Obstetrics & Gynecology

The importance of MTHFR, MTR, MTRR and CSE expression levels in Caucasian women with preeclampsia

Agnieszka Seremak-Mrozikiewicz et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2015)

添加到收藏夹

Article Medicine, General & Internal

Homocysteine and the C677T Gene Polymorphism of Its Key Metabolic Enzyme MTHFR Are Risk Factors of Early Renal Damage in Hypertension in a Chinese Han Population

Lin Yun et al.

MEDICINE (2015)

添加到收藏夹

Letter Obstetrics & Gynecology

The CCR5Δ32 polymorphism as a pre-eclampsia susceptibility marker: an evaluation in Brazilian women

Bianca Telini et al.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS (2014)

添加到收藏夹

Article Obstetrics & Gynecology

Endothelial nitric oxide synthase (eNOS) (Glu298Asp) and urotensin II (UTS2 S89N) gene polymorphisms in preeclampsia: prediction and correlation with severity in Egyptian females

Walid S. El-Sherbiny et al.

HYPERTENSION IN PREGNANCY (2013)

添加到收藏夹

Article Multidisciplinary Sciences

The Common Variant rs11646213 Is Associated with Preeclampsia in Han Chinese Women

Ji-peng Wan et al.

PLOS ONE (2013)

添加到收藏夹

Article Nutrition & Dietetics

MTHFR C677T and MTR A2756G polymorphisms and the homocysteine lowering efficacy of different doses of folic acid in hypertensive Chinese adults

Xianhui Qin et al.

NUTRITION JOURNAL (2012)

添加到收藏夹

Article Multidisciplinary Sciences

Role of C677T and A1298C MTHFR, A2756G MTR and-786 C/T eNOS Gene Polymorphisms in Atrial Fibrillation Susceptibility

Betti Giusti et al.

PLOS ONE (2007)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Risk index for perioperative renal dysfunction/failure - Critical dependence on pulse pressure hypertension

Solomon Aronson et al.

CIRCULATION (2007)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.