4.6 Article

Study of Antibodies to Influenza Neuraminidase N2

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Summary: The study found that escape mutations in NA antibodies can affect MAb binding, NA inhibition and neutralization activity, with mutations at K199 and E258 having the largest impact. Additionally, a natural isolate from the 2017-2018 season was found to be resistant to numerous antibodies, highlighting the importance of identifying novel human MAb epitopes on the N2.

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