Species-typical group size differentially influences social reward neural circuitry during nonreproductive social interactions

We investigated whether nonreproductive social interactions may be rewarding for colonial but not non-colonial species. We found that the colonial spiny mouse (Acomys cahirinus) is significantly more gregarious, more prosocial, and less aggressive than its non-colonial relative, theMongolian gerbil (Meriones unguiculatus). In an immediate-early gene study, we examined oxytocin (OT) and tyrosine hydroxylase (TH) neural responses to interactions with a novel, same-sex conspecific or a novel object. The paraventricular nucleus of the hypothalamus (PVN) OT cell group was more responsive to interactions with a conspecific compared to a novel object in both species. However, the ventral tegmental area (VTA) TH cell group showed differential responses only in spiny mice. Further, PVN OT and VTA TH neural responses positively correlated in spiny mice, suggesting functional connectivity. These results suggest that colonial species may have evolved neural mechanisms associated with reward in novel, nonreproductive social contexts to promote large group-living.

Automated summary

The study found that colonial spiny mice are more sociable, prosocial, and less aggressive compared to non-colonial species. Neural responses in colonial species to nonreproductive social interactions indicate the evolution of reward mechanisms associated with promoting large group living. Functional connectivity between oxytocin and tyrosine hydroxylase neural responses suggests the presence of neural mechanisms linked to reward in novel social contexts.