Acute Pulmonary Embolism in COVID-19: A Potential Connection between Venous Congestion and Thrombus Distribution

Article Pharmacology & Pharmacy

Anticoagulant Treatment Regimens in Patients with Covid-19: A Meta-Analysis

Anselm Jorda et al.

Summary: In patients with COVID-19, higher-dose anticoagulation compared to prophylactic-dose anticoagulation reduces the risk of thromboembolic events but increases the risk of major bleeding, with no significant impact on the risk of death.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2022)

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Article Radiology, Nuclear Medicine & Medical Imaging

Comparison of chest CT severity scoring systems for COVID-19

Ali H. Elmokadem et al.

Summary: This study compared the diagnostic performance and inter-observer agreement of different CT chest severity scoring systems for COVID-19, and found that CT-SS and TSS had the highest specificity and shortest interpretation time.

EUROPEAN RADIOLOGY (2022)

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Letter Critical Care Medicine

Pulmonary Vasculature: A Target for COVID-19

Lingdan Chen et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging

A new imaging sign in COVID-19 pneumonia: vascular changes and their correlation with clinical severity of the disease

Deniz Esin Tekcan Sanli et al.

Summary: The study found that specific vascular changes observed in chest CT of COVID-19 patients may predict the disease severity and could be related to respiratory distress. These changes were significantly associated with fever and shortness of breath, and were more remarkable in cases involving both upper and lower lobes.

DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY (2021)

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Article Multidisciplinary Sciences

Incidence and characterization of acute pulmonary embolism in patients with SARS-CoV-2 pneumonia: A multicenter Italian experience

Marco Loffi et al.

Summary: This study aimed to evaluate the occurrence of PE among SARS-CoV-2 infected patients, finding low risk factors for venous thromboembolism in PE patients, with most thrombi located in pneumonia areas within the pulmonary tree.

PLOS ONE (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging

Pulmonary vascular enlargement and lesion extent on computed tomography are correlated with COVID-19 disease severity

Ryo Aoki et al.

Summary: Pulmonary vascular enlargement and CT lesion extent are independent predictors of COVID-19 severity, and subsegmental vascular enlargement is a notable finding to predict acute disease severity.

JAPANESE JOURNAL OF RADIOLOGY (2021)

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Article Multidisciplinary Sciences

Massive image-based single-cell profiling reveals high levels of circulating platelet aggregates in patients with COVID-19

Masako Nishikawa et al.

Summary: The authors used massive single-cell image-based profiling to study circulating platelet aggregates in COVID-19 patients, revealing that nearly 90% of them had excessive platelet aggregates. The results also showed strong associations between the concentration of platelet aggregates and the severity, mortality, respiratory condition, and vascular endothelial dysfunction level of COVID-19 patients.

NATURE COMMUNICATIONS (2021)

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Article Medicine, General & Internal

Case Report: Intrapulmonary Arteriovenous Anastomoses in COVID-19-Related Pulmonary Vascular Changes: A New Player in the Arena?

Salah D. Qanadli et al.

Summary: The vascular changes related to COVID-19 have been mainly described as thrombo-embolic events, with a few reports of vascular dilation in the venous compartment. This vascular dilation may be caused by increased blood flow due to inflammation and the activation of arteriovenous anastomoses.

FRONTIERS IN MEDICINE (2021)

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Review Radiology, Nuclear Medicine & Medical Imaging

Diagnostic accuracy of CT and radiographic findings for novel coronavirus 2019 pneumonia: Systematic review and meta-analysis

Mandeep Garg et al.

Summary: By evaluating 56 studies, it was found that the combined prevalence of ground glass opacities and consolidation on chest CT is the highest, while radiographic abnormalities are visible in half of the patients. CT has a higher diagnostic performance for COVID-19 pneumonia, but should not be used as the primary tool for diagnosis.

CLINICAL IMAGING (2021)

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Article Medicine, General & Internal

Vascular Abnormalities Detected with Chest CT in COVID-19: Spectrum, Association with Parenchymal Lesions, Cardiac Changes, and Correlation with Clinical Severity (COVID-CAVA Study)

Salah D. Qanadli et al.

Summary: The Swiss national registry CAVA is a multicentric cohort study aimed at evaluating vascular and non-vascular-related CT findings in COVID-19 patients and their correlation with clinical outcomes. The main objective is to assess the prevalence of cardiovascular abnormalities, while secondary objectives include studying the predictive value of cardiovascular abnormalities in terms of disease severity and fatal outcomes.

DIAGNOSTICS (2021)

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Article

Anticoagulation in COVID-19: a review of current literature and guidelines

Bharat Narasimhan et al.

Hospital practice (1995) (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging

Role of CT angiography in detecting acute pulmonary embolism associated with COVID-19 pneumonia

Gabriele Masselli et al.

Summary: The study found that 40% of severe COVID-19 patients developed pulmonary embolism, with higher levels of D-dimer and CRP. Patients with PE were more likely to require intensive care and mechanical ventilation.

RADIOLOGIA MEDICA (2021)

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Letter Respiratory System

Reversibility of venous dilatation and parenchymal changes density in Sars-Cov-2 pneumonia: toward the definition of a peculiar pattern

S. Piciucchi et al.

PULMONOLOGY (2021)

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Review Medicine, General & Internal

Cardiovascular involvement in patients with 2019 novel coronavirus disease

Chenze Li et al.

Summary: The 2019 novel coronavirus disease (COVID-19) is caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), characterized by severe respiratory symptoms and widespread organ injuries. Cardiovascular impairment is a notable extrapulmonary manifestation, with reports reviewed and clinical characteristics summarized for frontline physicians, along with discussions on possible mechanisms and medication applications.

JOURNAL OF TRANSLATIONAL INTERNAL MEDICINE (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging