4.8 Editorial Material

Accounting for the genetic load in assisted reproductive technology

期刊

出版社

JOHN WILEY & SONS LTD
DOI: 10.1002/ctm2.864

关键词

assisted reproductive technology; deleterious mutations; genetic load; human fertility

资金

  1. Earth and Life Systems Alliance (ELSA), Norwich Research Park
  2. Biotechnology and Biological Sciences Research Council (BBSRC) - Doctoral Training Partnership
  3. European Research Council (ERC)

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This article discusses the significant impact of genetic load on assisted reproductive technology, human reproduction, and fertility. It explores these topics in the context of evolutionary genetic theory, the technological revolution in ART, and the advancements in genomics and bioinformatics.
The genetic load in the human genome has important ramifications for assisted reproductive technology (ART), human reproduction and fertility more generally. Here, we discuss these topics in the light of evolutionary genetic theory, the technological revolution in ART and the advances in the fields of genomics and bioinformatics.

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