Peptide-based nanomaterials: Self-assembly, properties and applications

Peptide-based materials that have diverse structures and functionalities are an important type of biomaterials. In former times, peptide-based nanomaterials with excellent stability were constructed through self-assembly. Compared with individual peptides, peptide-based self-assembly nanomaterials that form well-ordered superstructures possess many advantages such as good thermo- and mechanical stability, semiconductivity, piezoelectricity and optical properties. Moreover, due to their excellent biocompatibility and biological activity, peptide-based self-assembly nanomaterials have been vastly used in different fields. In this review, we provide the advances of peptide-based self-assembly nanostructures, focusing on the driving forces that dominate peptide self-assembly and assembly mechanisms of peptides. After that, we outline the synthesis and properties of peptide-based nanomaterials, followed by the applications of functional peptide nanomaterials. Finally, we provide perspectives on the challenges and future of peptide-based nanomaterials.

Automated summary

Peptide-based self-assembly nanomaterials, with diverse structures and functionalities, play a significant role in bioapplications. This review provides an overview of the recent advances in peptide-based self-assembly nanostructures, focusing on the driving forces and assembly mechanisms. It also summarizes the synthesis, properties, and applications of functional peptide nanomaterials. The challenges and future prospects of peptide-based nanomaterials are discussed.