Fabrication and characterization of a myrrh hydrocolloid dressing for dermal wound healing

Common occurrence of dermal injuries has made wound dressing a critical component in wound healing. Hy-drocolloid wound dressings have been developed as fanciful and effective wound dressing with ability for wound fluid control, adherence to wound site, and infection prevention. Effectiveness of topical application of myrrh resin to dermal wound has been well documented. We fabricated Mirderm hydrocolloid wound dressings with myrrh resin to enhance wound healing and improve on the mechanical characteristics of the hydrocolloid. The biocompatibility of Mirderm was assayed with CCK-8 while the wound healing efficacy was tested in vivo. The physical and mechanical properties were checked to affirm the suitability of Mirderm as hydrocolloid wound dressing. We observed Mirderm showed superior wound healing and mechanical capability suitable for hydro-colloid polymer relative to investigated commercial hydrocolloid and medical Gauze. These are indications that Mirderm may be an improvement on standard dressings such as Gauze and some commercial hydrocolloids.

Automated summary

Wound dressings play a critical role in wound healing. Hydrocolloid wound dressings have been developed as effective solutions for wound fluid control, adhering to the wound site, and preventing infection. This study aimed to enhance wound healing and improve the mechanical characteristics of hydrocolloid dressings by fabricating Mirderm, a hydrocolloid dressing infused with myrrh resin. The study found that Mirderm demonstrated superior wound healing and mechanical capabilities compared to commercially available hydrocolloid dressings and medical gauze, suggesting it may be an improvement over standard dressings.