Oxovanadium(V)-Catalyzed Synthesis of Ureas from Disilylamines and Carbon Dioxide under Ambient Pressure

Here, a commercially available easy-to-handle oxovanadium(V) compound is demonstrated to serve as an efficient catalyst for the synthesis of ureas from disilylamines and carbon dioxide under ambient pressure. The catalytic activation of carbon dioxide proceeds without any additives, demonstrating a broad substrate scope and easy scalability to validate this catalytic activation of carbon dioxide. This catalytic system can be applied to the synthesis of unsymmetric ureas and chiral urea with retention of chirality.

Automated summary

In this study, a commercially available and easy-to-handle oxovanadium(V) compound is shown to be an efficient catalyst for the synthesis of ureas from disilylamines and carbon dioxide under ambient pressure. The catalytic activation of carbon dioxide occurs without any additives, demonstrating a wide range of applicable substrates and easy scalability. Furthermore, this catalytic system can be used for the synthesis of unsymmetric ureas and chiral urea while retaining chirality.