期刊
PLANTS-BASEL
卷 11, 期 9, 页码 -出版社
MDPI
DOI: 10.3390/plants11091179
关键词
antiplatelet; antioxidant; common bean; ultrasonic assisted extraction; microwave assisted extraction
资金
- Centro de Estudios en Alimentos Procesados-CEAP
- Centro de Estudios en Alimentos Procesados-CEAP, ANID, Programa Regional, Talca, Chile [R20F0001]
This study investigated the antiplatelet and antioxidant potential of common bean landraces. Microwave-assisted extraction showed higher phenol content and antioxidant activity in most extracts. The extract obtained by ultrasound-assisted extraction from one landrace had the highest antiplatelet potential.
Phaseolus vulgaris L. has beneficial effects on several chronic non-communicable diseases (e.g., cardiovascular diseases) related to oxidative stress. This redox state may influence platelet activation and aggregation; which is crucial in thrombus formation. In this work, the antiplatelet and antioxidant potential of aqueous extracts obtained by green processes, microwave-assisted extraction and ultrasound-assisted extraction, from 25 landraces of common beans were investigated. Phenol content and antioxidant potential were determined using the Folin-Ciocalteu method, total monomeric anthocyanin and ORAC assay, respectively. The antiplatelet potential of the extracts was explored by turbidimetry. Microwave extraction showed higher phenol content and antioxidant activity in most extracts. Soja landrace extract obtained by microwave-assisted extraction showed higher phenol content and antioxidant activity (893.45 +/- 87.30 mg GAE/g and 35,642.85 +/- 2588.88 ORAC mu molTE/g, respectively). Although most of the extracts obtained by microwave-assisted extraction showed antiplatelet activity, the extract of Hallado Aleman landrace obtained by ultrasound-assisted extraction (IC50 = 0.152 +/- 0.018 mg/mL) had the highest antiplatelet potential. The extraction method, MAE and UAE, influences the biological potential of the beans, specifically the antiplatelet activity and antioxidant activity. The functional value of this legume for direct consumption by the population was evidenced, as well as its inclusion in food formulations.
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