相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Cancer statistics, 2022
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2022)
MR-guided adaptive stereotactic body radiotherapy (SBRT) of primary tumor for pain control in metastatic pancreatic ductal adenocarcinoma (mPDAC): an open randomized, multicentric, parallel group clinical trial (MASPAC)
M. Pavic et al.
RADIATION ONCOLOGY (2022)
Repurposing of Auranofin Against Bacterial Infections: An In silico and In vitro Study
Nidhi Sharma et al.
CURRENT COMPUTER-AIDED DRUG DESIGN (2021)
Combined treatment with auranofin and trametinib induces synergistic apoptosis in breast cancer cells
Min-Kyung Joo et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES (2021)
Ascorbate kills breast cancer cells by rewiring metabolism via redox imbalance and energy crisis
Ali Ghanem et al.
FREE RADICAL BIOLOGY AND MEDICINE (2021)
Combination of Auranofin and ICG-001 Suppress the Proliferation and Metastasis of Colon Cancer
Zhaoyan Lin et al.
FRONTIERS IN ONCOLOGY (2021)
Current status of non-surgical treatment of locally advanced pancreatic cancer
Stavros Spiliopoulos et al.
WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY (2021)
Catalase Modulates the Radio-Sensitization of Pancreatic Cancer Cells by Pharmacological Ascorbate
Juan Du et al.
ANTIOXIDANTS (2021)
Stereotactic Versus Conventional Radiation Therapy for Patients With Pancreatic Cancer in the Modern Era
Joseph Abi Jaoude et al.
ADVANCES IN RADIATION ONCOLOGY (2021)
Pancreatic cancer: A review of epidemiology, trend, and risk factors
Jian-Xiong Hu et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2021)
Phase I study of dose-escalated stereotactic body radiation therapy for locally advanced pancreatic head cancers: Initial clinical results
Shuiwang Qing et al.
CANCER MEDICINE (2021)
Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer
Laurie Freire Boullosa et al.
REDOX BIOLOGY (2021)
Repurposing auranofin as a Clostridioides difficile therapeutic
Melanie L. Hutton et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2020)
Pharmacological ascorbate induces 'BRCAness' and enhances the effects of Poly(ADP-Ribose) polymerase inhibitors against BRCA1/2 wild-type ovarian cancer
Yan Ma et al.
ONCOLOGY LETTERS (2020)
Comprehensive chemical proteomics for target deconvolution of the redox active drug auranofin
Amir Ata Saei et al.
REDOX BIOLOGY (2020)
Survival of pancreatic cancer patients is negatively correlated with age at diagnosis: a population-based retrospective study
Hongcheng Wang et al.
SCIENTIFIC REPORTS (2020)
The actual 5-year survivors of pancreatic ductal adenocarcinoma based on real-world data
Axel Bengtsson et al.
SCIENTIFIC REPORTS (2020)
Auranofin/Vitamin C: A Novel Drug Combination Targeting Triple-Negative Breast Cancer
Elie Hatem et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2019)
Pancreatic Adenocarcinoma, Version 1.2019
Margaret A. Tempero et al.
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK (2019)
Inhibition of thioredoxin-dependent H2O2 removal sensitizes malignant B-cells to pharmacological ascorbate
Agnieszka Graczyk-Jarzynka et al.
REDOX BIOLOGY (2019)
Combination treatment with auranofin and nutlin-3a induces synergistic cytotoxicity in breast cancer cells
Dong-Jin Ye et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES (2019)
Enhanced Pharmacological Ascorbate Oxidation Radiosensitizes Pancreatic Cancer
Matthew S. Alexander et al.
RADIATION RESEARCH (2019)
Pharmacological Ascorbate as a Means of Sensitizing Cancer Cells to Radio Chemotherapy While Protecting Normal Tissue
Joshua D. Schoenfeld et al.
SEMINARS IN RADIATION ONCOLOGY (2019)
Targeting cancer vulnerabilities with high-dose vitamin C
Bryan Ngo et al.
NATURE REVIEWS CANCER (2019)
A role for 2-Cys peroxiredoxins in facilitating cytosolic protein thiol oxidation
Sarah Stoecker et al.
NATURE CHEMICAL BIOLOGY (2018)
The Conundrum of Hydrogen Peroxide Signaling and the Emerging Role of Peroxiredoxins as Redox Relay Hubs
Sarah Stoecker et al.
ANTIOXIDANTS & REDOX SIGNALING (2018)
Pharmacologic Ascorbate Reduces Radiation-Induced Normal Tissue Toxicity and Enhances Tumor Radiosensitization in Pancreatic Cancer
Matthew S. Alexander et al.
CANCER RESEARCH (2018)
Auranofin Enhances Ibrutinib's Anticancer Activity in EGFR-Mutant Lung Adenocarcinoma
Jing Hu et al.
MOLECULAR CANCER THERAPEUTICS (2018)
FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer
T. Conroy et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
Chemotherapy and radiotherapy for advanced pancreatic cancer
Venessa Chin et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2018)
Inhibition of Peroxide Removal Enhances Pharmacological Ascorbate and Ionizing Radiation-Induced Cytotoxicity of Pancreatic Ductal Adenocarcinoma
Brianne O'Leary et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Pancreatic Adenocarcinoma, Version 2.2017
Margaret A. Tempero et al.
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK (2017)
High Dose Parenteral Ascorbate Inhibited Pancreatic Cancer Growth and Metastasis: Mechanisms and a Phase I/IIa study
Kishore Polireddy et al.
SCIENTIFIC REPORTS (2017)
Synergistic induction of apoptosis by combination treatment with mesupron and auranofin in human breast cancer cells
Joo-Eun Lee et al.
ARCHIVES OF PHARMACAL RESEARCH (2017)
O2•- and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate
Joshua D. Schoenfeld et al.
CANCER CELL (2017)
Effect of Chemoradiotherapy vs Chemotherapy on Survival in Patients With Locally Advanced Pancreatic Cancer Controlled After 4 Months of Gemcitabine With or Without Erlotinib The LAP07 Randomized Clinical Trial
Pascal Hammel et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)
Oxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signaling in Aging Chondrocytes
John A. Collins et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Tumor cells have decreased ability to metabolize H2O2: Implications for pharmacological ascorbate in cancer therapy
Claire M. Doskey et al.
REDOX BIOLOGY (2016)
The DNA Damage Response: Implications for Tumor Responses to Radiation and Chemotherapy
Michael Goldstein et al.
ANNUAL REVIEW OF MEDICINE, VOL 66 (2015)
Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer
Juan Du et al.
CANCER RESEARCH (2015)
Manganoporphyrins and ascorbate enhance gemcitabine cytotoxicity in pancreatic cancer
John A. Cieslak et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Progression-free survival as surrogate endpoint in advanced pancreatic cancer: meta-analysis of 30 randomized first-line trials
Fausto Petrelli et al.
HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL (2015)
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH
Jihye Yun et al.
SCIENCE (2015)
Peroxiredoxin 1 suppresses apoptosis via regulation of the apoptosis signal-regulating kinase 1 signaling pathway in human oral leukoplakia
Min Zhang et al.
ONCOLOGY LETTERS (2015)
Peroxiredoxin-2 and STAT3 form a redox relay for H2O2 signaling
Mirko C. Sobotta et al.
NATURE CHEMICAL BIOLOGY (2015)
The thioredoxin antioxidant system
Jun Lu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2014)
Auranofin displays anticancer activity against ovarian cancer cells through FOXO3 activation independent of p53
See-Hyoung Park et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
Pharmacological ascorbate with gemcitabine for the control of metastatic and node-positive pancreatic cancer (PACMAN): results from a phase I clinical trial
J. L. Welsh et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2013)
Inhibitors of hydroperoxide metabolism enhance ascorbate-induced cytotoxicity
K. E. Olney et al.
FREE RADICAL RESEARCH (2013)
Pancreatic cancer: why is it so hard to treat?
Paul E. Oberstein et al.
THERAPEUTIC ADVANCES IN GASTROENTEROLOGY (2013)
Ascorbic acid: Chemistry, biology and the treatment of cancer
Juan Du et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2012)
Inactivation of a Peroxiredoxin by Hydrogen Peroxide Is Critical for Thioredoxin-Mediated Repair of Oxidized Proteins and Cell Survival
Alison M. Day et al.
MOLECULAR CELL (2012)
Phase I Evaluation of Intravenous Ascorbic Acid in Combination with Gemcitabine and Erlotinib in Patients with Metastatic Pancreatic Cancer
Daniel A. Monti et al.
PLOS ONE (2012)
Gold drug auranofin restricts the viral reservoir in the monkey AIDS model and induces containment of viral load following ART suspension
Mark G. Lewis et al.
AIDS (2011)
Auranofin Protects against Anthrax Lethal Toxin-Induced Activation of the Nlrp1b Inflammasome
Zachary L. Newman et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2011)
Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer
Michael Graham Espey et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Model for the Exceptional Reactivity of Peroxiredoxins 2 and 3 with Hydrogen Peroxide A KINETIC AND COMPUTATIONAL STUDY
Peter Nagy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Auranofin protects against cocaine-induced hepatic injury through induction of heme oxygenase-1
Takashi Ashino et al.
JOURNAL OF TOXICOLOGICAL SCIENCES (2011)
FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
Thierry Conroy et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Practical approaches to effective management of intestinal radiation injury: Benefit of resectional surgery
Nikolaos Perrakis et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2011)
Thioredoxin and thioredoxin reductase: Current research with special reference to human disease
Arne Holmgren et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Mechanisms of Ascorbate-Induced Cytotoxicity in Pancreatic Cancer
Juan Du et al.
CLINICAL CANCER RESEARCH (2010)
Structural analysis of the anti-arthritic drug Auranofin: Its complexes with cysteine, selenocysteine and their fragmentation products
Tamer Shoeib et al.
INORGANICA CHIMICA ACTA (2010)
Auranofin, a Gold(I)-Containing Antirheumatic Compound, Activates Keap1/Nrf2 Signaling via Rac1/iNOS Signal and Mitogen-Activated Protein Kinase Activation
Nam-Hoon Kim et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2010)
Metastatic pancreatic cancer: Is gemcitabine still the best standard treatment? (Review)
Mariacristina Di Marco et al.
ONCOLOGY REPORTS (2010)
Pharmacologic concentrations of ascorbate are achieved by parenteral administration and exhibit antitumoral effects
Julien Verrax et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
Auranofin inhibits overproduction of pro-inflammatory cytokines, cyclooxygenase expression and PGE(2) production in macrophages
Shinha Han et al.
ARCHIVES OF PHARMACAL RESEARCH (2008)
Auranofin, an immunosuppressive drug, inhibits MHC class I and MHC class II pathways of antigen presentation in dendritic cells
Shinha Han et al.
ARCHIVES OF PHARMACAL RESEARCH (2008)
The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation
Andrew G. Cox et al.
BIOCHEMICAL PHARMACOLOGY (2008)
A novel function of peroxiredoxin 1 (Prx-1) in apoptosis signal-regulating kinase 1 (ASK1)-mediated signaling pathway
So Yong Kim et al.
FEBS LETTERS (2008)
New uses for old drugs.: Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro:: Mechanistic and pharmacological implications
Anna Rosa Sannella et al.
FEBS LETTERS (2008)
Current topics in DNA double-strand break repair
Junya Kobayashi et al.
JOURNAL OF RADIATION RESEARCH (2008)
Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice
Qi Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
SVCT1 and SVCT2: key proteins for vitamin C uptake
I. Savini et al.
AMINO ACIDS (2008)
Auranofin blocks interleukin-6 signalling by inhibiting phosphorylation of JAK1 and STAT3
Nam-Hoon Kim et al.
IMMUNOLOGY (2007)
Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo
Qi Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Peroxiredoxin 2 functions as a noncatalytic scavenger of low-level hydrogen peroxide in the erythrocyte
Felicia M. Low et al.
BLOOD (2007)
Reactions of yeast thioredoxin peroxidases I and II with hydrogen peroxide and peroxynitrite: Rate constants by competitive kinetics
Renata Ogusucu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
The role of p38 MAPK activation in auranofin-induced apoptosis of human promyelocytic leukaemia HL-60 cells
SJ Park et al.
BRITISH JOURNAL OF PHARMACOLOGY (2005)
Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues
Q Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Anti-rheumatic gold compounds as sublethal modulators of monocytic LPS-induced cytokine secretion
I Stern et al.
TOXICOLOGY IN VITRO (2005)
Vitamin C pharmacokinetics: Implications for oral and intravenous use
SJ Padayatty et al.
ANNALS OF INTERNAL MEDICINE (2004)
Redox regulation of pancreatic cancer cell growth: Role of glutathione peroxidase in the suppression of the malignant phenotype
JR Liu et al.
HUMAN GENE THERAPY (2004)
Cytosolic peroxiredoxin attenuates the activation of JNK and p38 but potentiates that of ERK in HeLa cells stimulated with tumor necrosis factor-α
SW Kang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Peroxiredoxin III, a mitochondrion-specific peroxidase, regulates apoptotic signaling by mitochondria
TS Chang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
A new recommended dietary allowance of vitamin C for healthy young women
M Levine et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple
FQ Schafer et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
Role of peroxiredoxins in regulating intracellular hydrogen peroxide and hydrogen peroxide-induced apoptosis in thyroid cells
H Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation
BM Sutherland et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
分享论文
