4.7 Article

Tau Protein Modulates Perineuronal Extracellular Matrix Expression in the TauP301L-acan Mouse Model

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Neurosciences

Aggrecan modulates the expression and phosphorylation of tau in a novel bigenic TauP301L-Acan mouse model

Sophie Schmidt et al.

Summary: Selected neurons in the central nervous system are surrounded by perineuronal nets (PNs) which regulate plasticity and synaptic physiology. Research showed that aggrecan, a component of PNs, has a neuroprotective role by preventing internalization of pathological tau forms. However, in a mouse model, reduced aggrecan levels led to increased tau protein and phosphorylation, suggesting a correlation between aggrecan and tau pathology triggered by mutation.

EUROPEAN JOURNAL OF NEUROSCIENCE (2021)

Article Multidisciplinary Sciences

Microglia become hypofunctional and release metalloproteases and tau seeds when phagocytosing live neurons with P301S tau aggregates

Jack H. Brelstaff et al.

Summary: The study reveals that tau protein aggregation in neurons can trigger inflammation and cellular senescence in microglia, leading to impaired phagocytic function and release of tau aggregates. This process facilitates the spreading of tau protein, indicating a potential mechanism for neurodegenerative diseases.

SCIENCE ADVANCES (2021)

Article Oncology

The prognostic and diagnostic value of tissue inhibitor of metalloproteinases gene family and potential function in gastric cancer

Zhao Li et al.

Summary: This study investigated the diagnostic and prognostic value of TIMP gene family in gastric cancer using data from TCGA. Results indicated that TIMP1, TIMP3, and TIMP4 have potential diagnostic value, while TIMP2 and TIMP3 are associated with overall survival. Functional analysis revealed the potential mechanisms and effects of TIMP genes on gastric cancer cell behavior, suggesting their potential as biomarkers for diagnosis and prognosis in GC.

JOURNAL OF CANCER (2021)

Article Biochemistry & Molecular Biology

A synthetic heparinoid blocks Tau aggregate cell uptake and amplification

Barbara E. Stopschinski et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2020)

Article Neurosciences

Analysis of the Relationship Between Metalloprotease-9 and Tau Protein in Alzheimer's Disease

Mario Hernandes-Alejandro et al.

JOURNAL OF ALZHEIMERS DISEASE (2020)

Article Neurosciences

Neurocan Contributes to Perineuronal Net Development

Sophie Schmidt et al.

NEUROSCIENCE (2020)

Review Pharmacology & Pharmacy

The potential of memory enhancement through modulation of perineuronal nets

James A. Duncan et al.

BRITISH JOURNAL OF PHARMACOLOGY (2019)

Article Medical Laboratory Technology

Dynamics of extracellular matrix proteins in cerebrospinal fluid and serum and their relation to clinical outcome in human traumatic brain injury

Karolina Minta et al.

CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2019)

Review Biochemistry & Molecular Biology

Metalloproteinases and their tissue inhibitors in Alzheimer's disease and other neurodegenerative disorders

Santiago Rivera et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2019)

Review Neurosciences

Tau Secretion: Good and Bad for Neurons

Camille Pernegre et al.

FRONTIERS IN NEUROSCIENCE (2019)

Review Cell Biology

Perineuronal nets in brain physiology and disease

Damien Testa et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2019)

Article Multidisciplinary Sciences

Generation of a whole-brain atlas for the cholinergic system and mesoscopic projectome analysis of basal forebrain cholinergic neurons

Xiangning Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Neurosciences

Prion-like Spreading in Tauopathies

Jacob I. Ayers et al.

BIOLOGICAL PSYCHIATRY (2018)

Article Biochemistry & Molecular Biology

An N-terminal motif unique to primate tau enables differential protein-protein interactions

Kristie Stefanoska et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Review Genetics & Heredity

Releasing Addiction Memories Trapped in Perineuronal Nets

Amy W. Lasek et al.

TRENDS IN GENETICS (2018)

Review Neurosciences

Extracellular Tau and Its Potential Role in the Propagation of Tau Pathology

Kaoru Yamada

FRONTIERS IN NEUROSCIENCE (2017)

Review Neurosciences

What is the evidence that tau pathology spreads through prion-like propagation?

Amrit Mudher et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2017)

Article Clinical Neurology

Profiling the human hippocampal proteome at all pathologic stages of Alzheimer's disease

David C. Hondius et al.

ALZHEIMERS & DEMENTIA (2016)

Article Neurosciences

Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity

Barbara A. Sorg et al.

JOURNAL OF NEUROSCIENCE (2016)

Article Pharmacology & Pharmacy

ADAMTS4, 5, 9, and 15 Expressions in the Autopsied Brain of Patients with Alzheimer's Disease: A Preliminary Immunohistochemistry Study

Sultan Pehlivan et al.

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY (2016)

Review Biochemistry & Molecular Biology

Looking Inside the Matrix: Perineuronal Nets in Plasticity, Maladaptive Plasticity and Neurological Disorders

Ciro De Luca et al.

NEUROCHEMICAL RESEARCH (2016)

Article Clinical Neurology

Tauopathies as clinicopathological entities

David J. Irwin

PARKINSONISM & RELATED DISORDERS (2016)

Article Neurosciences

Protective Properties of Neural Extracellular Matrix

Anne Suttkus et al.

MOLECULAR NEUROBIOLOGY (2016)

Review Audiology & Speech-Language Pathology

Perineuronal nets in the auditory system

Mandy Sonntag et al.

HEARING RESEARCH (2015)

Article Multidisciplinary Sciences

AIM2 Drives Joint Inflammation in a Self-DNA Triggered Model of Chronic Polyarthritis

Christopher Jakobs et al.

PLOS ONE (2015)

Review Biochemistry & Molecular Biology

Tau Protein Modifications and Interactions: Their Role in Function and Dysfunction

Anna Mietelska-Porowska et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

Article Neurosciences

Neuroprotective role of MMP-9 overexpression in the brain of Alzheimer's 5xFAD mice

Apostolia Fragkouli et al.

NEUROBIOLOGY OF DISEASE (2014)

Review Neurosciences

The role of extracellular Tau in the spreading of neurofibrillary pathology

Miguel Medina et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2014)

Review Biotechnology & Applied Microbiology

Matrix Metalloproteinases and Their Multiple Roles in Alzheimer's Disease

Xiang-Xiang Wang et al.

BIOMED RESEARCH INTERNATIONAL (2014)

Article Neurosciences

Reducing hippocampal extracellular matrix reverses early memory deficits in a mouse model of Alzheimer's disease

Marlene J. Vegh et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2014)

Article Multidisciplinary Sciences

Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

Brandon B. Holmes et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Cell Biology

The perineuronal net and the control of CNS plasticity

Difei Wang et al.

CELL AND TISSUE RESEARCH (2012)

Article Biochemistry & Molecular Biology

Aggrecan: Beyond cartilage and into the brain

M. Morawski et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2012)

Article Biochemistry & Molecular Biology

Tau Oligomers Impair Artificial Membrane Integrity and Cellular Viability

Katharina Flach et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Clinical Neurology

Tau Overexpression Results in Its Secretion via Membrane Vesicles

Diana Simon et al.

NEURODEGENERATIVE DISEASES (2012)

Article Neurosciences

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

Alix de Calignon et al.

NEURON (2012)

Article Multidisciplinary Sciences

Trans-Synaptic Spread of Tau Pathology In Vivo

Li Liu et al.

PLOS ONE (2012)

Review Medical Laboratory Technology

Metalloproteinases in metabolic syndrome

Gabriela Berg et al.

CLINICA CHIMICA ACTA (2011)

Article Developmental Biology

Extracellular Matrix and Perineuronal Nets in CNS Repair

Jessica C. F. Kwok et al.

DEVELOPMENTAL NEUROBIOLOGY (2011)

Article Biochemical Research Methods

Coomassie Staining as Loading Control in Western Blot Analysis

Charlotte Welinder et al.

JOURNAL OF PROTEOME RESEARCH (2011)

Review Biotechnology & Applied Microbiology

Tissue inhibitors of metalloproteinases

Gillian Murphy

GENOME BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

Lars M. Ittner et al.

Article Clinical Neurology

Tau in Alzheimer Disease and Related Tauopathies

K. Iqbal et al.

CURRENT ALZHEIMER RESEARCH (2010)

Article Psychology, Clinical

Matrix metalloproteinases in peripheral blood and cerebrospinal fluid in patients with Alzheimer's disease

Solveig Horstmann et al.

INTERNATIONAL PSYCHOGERIATRICS (2010)

Article Neurosciences

Interneuronal Transfer of Human Tau Between Lamprey Central Neurons in situ

WonHee Kim et al.

JOURNAL OF ALZHEIMERS DISEASE (2010)

Article Neurosciences

PERINEURONAL NET FORMATION AND STRUCTURE IN AGGRECAN KNOCKOUT MICE

K. A. Giamanco et al.

NEUROSCIENCE (2010)

Article Biochemistry & Molecular Biology

Brevican distinctively assembles extracellular components at the large diameter nodes of Ranvier in the CNS

Yoko Bekku et al.

JOURNAL OF NEUROCHEMISTRY (2009)

Article Pharmacology & Pharmacy

Matrix Metalloprotease-9 Inhibition Improves Amyloid β-Mediated Cognitive Impairment and Neurotoxicity in Mice

Hiroyuki Mizoguchi et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)

Review Cell Biology

Extracellular matrix of the central nervous system: from neglect to challenge

Dieter R. Zimmermann et al.

HISTOCHEMISTRY AND CELL BIOLOGY (2008)

Article Cell Biology

Chondroitin-4-sulfation negatively regulates axonal guidance and growth

Hang Wang et al.

JOURNAL OF CELL SCIENCE (2008)

Article Clinical Neurology

Elevated matrix metalloproteinase-9 and degradation of perineuronal nets in cerebrocortical multiple sclerosis plaques

Elizabeth Gray et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)

Review Cell Biology

MMPs in the central nervous system: Where the good guys go bad

Smriti M. Agrawal et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Interaction of tau protein with the dynactin complex

Enrico Magnani et al.

EMBO JOURNAL (2007)

Review Neurosciences

Matrix metalloproteinases in brain development and remodeling: Synaptic functions and targets

Iryna M. Ethell et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2007)

Article Biochemistry & Molecular Biology

Mapping of aggrecan, hyaluronic acid, heparan sulphate proteoglycans and aquaporin 4 in the central nervous system of the mouse

Carme Costa et al.

JOURNAL OF CHEMICAL NEUROANATOMY (2007)

Review Neurosciences

Matrix metalloproteinases and proteoglycans in axonal regeneration

Michael A. Pizzi et al.

EXPERIMENTAL NEUROLOGY (2007)

Article Biochemistry & Molecular Biology

Extracellular tau is toxic to neuronal cells

Alberto Gomez-Ramos et al.

FEBS LETTERS (2006)

Article Biochemistry & Molecular Biology

Composition of perineuronal net extracellular matrix in rat brain - A different disaccharide composition for the net-associated proteoglycans

Sarama Sathyaseelan Deepa et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Disease-related modifications in tau affect the interaction between Fyn and tau

K Bhaskar et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Selective vulnerability of dopaminergic neurons to microtubule depolymerization

Y Ren et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Neurosciences

Neurotrophins are required for nerve growth during development

KL Tucker et al.

NATURE NEUROSCIENCE (2001)

Review Neurosciences

Neurodegenerative tauopathies

VMY Lee et al.

ANNUAL REVIEW OF NEUROSCIENCE (2001)

Article Biochemistry & Molecular Biology

Brevican is degraded by matrix metalloproteinases and aggrecanase-1 (ADAMTS4) at different sites

H Nakamura et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Review Neurosciences

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders

L Buée et al.

BRAIN RESEARCH REVIEWS (2000)