4.7 Article

Progesterone Attenuates SIRT1-Deficiency-Mediated Pre-Eclampsia

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Endocrinology & Metabolism

Role of SIRT1 and Progesterone Resistance in Normal and Abnormal Endometrium

Tae Hoon Kim et al.

Summary: The study revealed that SIRT1 expression in the endometrium is associated with progesterone resistance and normal endometrial function, while aberrant SIRT1 expression may contribute to progesterone resistance and the pathophysiology of endometriosis. SIRT1 serves as a novel and targetable protein for the diagnosis and treatment of endometriosis and infertility associated with this disease.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

Article Cell Biology

Advanced Maternal Age-associated SIRT1 Deficiency Compromises Trophoblast Epithelial-Mesenchymal Transition through an Increase in Vimentin Acetylation

Liling Xiong et al.

Summary: SIRT1 is downregulated in AMA placentas, affecting cell function and migration, leading to premature senescence. SIRT1 promotes trophoblast epithelial-mesenchymal transition (EMT) by modulating vimentin acetylation.

AGING CELL (2021)

Article Physiology

Progesterone-induced blocking factor improves blood pressure, inflammation, and pup weight in response to reduced uterine perfusion pressure (RUPP)

Jesse N. Cottrell et al.

Summary: The study demonstrates that PIBF can improve hypertension caused by preeclampsia by reducing inflammation and enhancing fetal growth, which has been confirmed in a rat model.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2021)

Article Reproductive Biology

Sirt1 and Nrf2: regulation of Leydig cell oxidant/antioxidant intracellular environment and steroid formation

Jin-Yong Chung et al.

Summary: Inhibition or knockout of Sirt1 or Nrf2 resulted in increased ROS and reduced cell testosterone production, and their activation protected or enhanced steroidogenic function, suggesting that Sirt1 and Nrf2 are involved in maintaining the Leydig cell oxidant/antioxidant environment and steroid production.

BIOLOGY OF REPRODUCTION (2021)

Article Medicine, General & Internal

Use of metformin to prolong gestation in preterm pre-eclampsia: randomised, double blind, placebo controlled trial

Catherine A. Cluver et al.

Summary: Extended release metformin can prolong gestation in women with preterm preeclampsia undergoing expectant management, with potential benefits on neonatal nursery stay. Further trials are needed to confirm these findings.

BMJ-BRITISH MEDICAL JOURNAL (2021)

Article Obstetrics & Gynecology

Aspirin enhances the protective effect of progesterone on trophoblast cell from oxidative stress and apoptosis

Jia-Wei Shi et al.

Summary: Low-dose aspirin and progesterone, either alone or in combination, were found to promote proliferation and invasion while reducing oxidative stress and apoptosis in trophoblasts in vitro, with the combined treatment showing stronger effects. The study may provide an experimental basis for using aspirin and progesterone together to prevent unexplained recurrent spontaneous miscarriage, especially in cases of trophoblast dysfunction.

REPRODUCTIVE AND DEVELOPMENTAL MEDICINE (2021)

Article Endocrinology & Metabolism

Sustained Maternal Hyperandrogenism During PCOS Pregnancy Reduced by Metformin in Non-obese Women Carrying a Male Fetus

Frida Andrae et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2020)

Article Cell Biology

SIRT1 is downregulated by autophagy in senescence and ageing

Caiyue Xu et al.

NATURE CELL BIOLOGY (2020)

Article Obstetrics & Gynecology

Gestational Hypertension and Preeclampsia

Jimmy Espinoza et al.

OBSTETRICS AND GYNECOLOGY (2020)

Article Biochemistry & Molecular Biology

SIRT2 plays a novel role on progesterone, estradiol and testosterone synthesis via PPARs/LXRα pathways in bovine ovarian granular cells

Dejun Xu et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2019)

Article Cardiac & Cardiovascular Systems

Preeclampsia Pathophysiology, Challenges, and Perspectives

Sarosh Rana et al.

CIRCULATION RESEARCH (2019)

Article Medicine, General & Internal

Long-Term Weight Loss With Metformin or Lifestyle Intervention in the Diabetes Prevention Program Outcomes Study

John W. Apolzan et al.

ANNALS OF INTERNAL MEDICINE (2019)

Review Endocrinology & Metabolism

Metformin reduces maternal weight gain in obese pregnant women: A systematic review and meta-analysis of two randomized controlled trials

Valentina D'Ambrosio et al.

DIABETES-METABOLISM RESEARCH AND REVIEWS (2019)

Article Medicine, Research & Experimental

SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition

Zhen-Hua Liu et al.

BIOMEDICINE & PHARMACOTHERAPY (2019)

Article Endocrinology & Metabolism

SRT2104 attenuates diabetes-induced aortic endothelial dysfunction via inhibition of P53

Hao Wu et al.

JOURNAL OF ENDOCRINOLOGY (2018)

Review Endocrinology & Metabolism

The role of Sirtuin1-PPARγ axis in placental development and function

Jonathan Pham et al.

JOURNAL OF MOLECULAR ENDOCRINOLOGY (2018)

Article Genetics & Heredity

MicroRNA-34a targets sirtuin 1 and leads to diabetes-induced testicular apoptotic cell death

Dan Jiao et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2018)

Article Obstetrics & Gynecology

Role of metformin for ovulation induction in infertile patients with polycystic ovary syndrome (PCOS): a guideline

Heather Huddleston et al.

FERTILITY AND STERILITY (2017)

Article Medicine, General & Internal

Alterations in antioxidant system, mitochondrial biogenesis and autophagy in preeclamptic myometrium

Polina A. Vishnyakova et al.

BBA CLINICAL (2017)

Article Cardiac & Cardiovascular Systems

CD74-Downregulation of Placental Macrophage-Trophoblastic Interactions in Preeclampsia

Lukasz Przybyl et al.

CIRCULATION RESEARCH (2016)

Article Biochemistry & Molecular Biology

Successful prevention of preeclampsia in a high-risk pregnancy using progestogen dydrogesterone: a clinical case

Vitaly B. Tskhay et al.

HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION (2016)

Article Biochemistry & Molecular Biology

Dydrogesterone support following assisted reproductive technique (ART) reduces the risk of pre-eclampsia

Anizah Bt Ali et al.

HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION (2016)

Article Cardiac & Cardiovascular Systems

Epidemiology and Mechanisms of De Novo and Persistent Hypertension in the Postpartum Period

Arvind Goel et al.

CIRCULATION (2015)

Article Obstetrics & Gynecology

Progesterone blunts vascular endothelial cell secretion of endothelin-1 in response to placental ischemia

Luissa V. Kiprono et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2013)

Review Medicine, Research & Experimental

The sirtuin family's role in aging and age-associated pathologies

Jessica A. Hall et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Biochemistry & Molecular Biology

Role of SIRT1 and FOXO factors in eNOS transcriptional activation by resveratrol

Ning Xia et al.

NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2013)

Article Cardiac & Cardiovascular Systems

Cardiovascular Effects of a Novel SIRT1 Activator, SRT2104, in Otherwise Healthy Cigarette Smokers

Sowmya Venkatasubramanian et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2013)

Review Endocrinology & Metabolism

Sirtuin 1 (SIRT1) and steroid hormone receptor activity in cancer

R. L. Moore et al.

JOURNAL OF ENDOCRINOLOGY (2012)

Review Cell Biology

The regulation of embryo implantation and endometrial decidualization by progesterone receptor signaling

Michael J. Large et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2012)

Review Pathology

Mammalian Sirtuins: Biological Insights and Disease Relevance

Marcia C. Haigis et al.

ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)

Article Cardiac & Cardiovascular Systems

AMP-Activated Protein Kinase Functionally Phosphorylates Endothelial Nitric Oxide Synthase Ser633

Zhen Chen et al.

CIRCULATION RESEARCH (2009)

Editorial Material Medicine, General & Internal

The global challenge of diabetes

[Anonymous]

LANCET (2008)

Article Obstetrics & Gynecology

Autophagy-Related Proteins, LC3 and Beclin-1, in Placentas From Pregnancies Complicated by Preeclampsia

Soo-Young Oh et al.

REPRODUCTIVE SCIENCES (2008)

Article Medicine, General & Internal

Metformin versus insulin for the treatment of gestational diabetes

Janet A. Rowan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

Article Multidisciplinary Sciences

SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase

Ilwola Mattagajasingh et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

B Rogina et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Review Genetics & Heredity

Placental development: Lessons from mouse mutants

J Rossant et al.

NATURE REVIEWS GENETICS (2001)

Article Multidisciplinary Sciences

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

HA Tissenbaum et al.

NATURE (2001)

Article Cardiac & Cardiovascular Systems

Regression of chronic L-NAME-treatment-induced left ventricular hypertrophy:: Effect of captopril

I Bernatova et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2000)