期刊
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
卷 10, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fbioe.2022.859927
关键词
hydrogel; extracellular vesicles; biomaterials; secretome; mesenchymal stem cells
资金
- National Natural Science Foundation of China [81970663]
- Natural Science Foundation of Liaoning Province [2019-BS-277]
Hydrogels, as representatives of biomaterials, have attracted much attention in the medical field. This review studies the safety and feasibility of hydrogel-encapsulated mesenchymal stem cells (MSCs), as well as the enhancement of therapeutic effect through hydrogels.
Biomaterials have long been the focus of research and hydrogels are representatives thereof. Hydrogels have attracted much attention in the medical sciences, especially as a candidate drug-carrier. Mesenchymal stem cells (MSC) and MSC-derived secretome are a promising therapeutic method, owing to the intrinsic therapeutic properties thereof. The low cell retention and poor survival rate of MSCs make further research difficult, which is a problem that hydrogel encapsulation largely solved. In this review, safety and feasibility of hydrogel-encapsulated MSCs, the improvement of the survival, retention, and targeting, and the enhancement of their therapeutic effect by hydrogels were studied. The status of the hydrogel-encapsulated MSC secretome was also discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据