4.7 Article

Epigenetic Clocks for Mice Based on Age-Associated Regions That are Conserved Between Mouse Strains and Human

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

A mammalian methylation array for profiling methylation levels at conserved sequences

Adriana Arneson et al.

Summary: The authors developed a Mammalian Methylation Array that includes 36k well-conserved CpGs in mammals, facilitating cross-species comparisons. They annotated the conserved CpGs in > 200 species. The array allows one to measure methylation in all mammalian species, including unsequenced ones.

NATURE COMMUNICATIONS (2022)

Review Cell Biology

How to Translate DNA Methylation Biomarkers Into Clinical Practice

Wolfgang Wagner

Summary: Recent advances in sequencing technologies have provided opportunities for the development of epigenetic biomarkers. However, only a few of them have been successfully translated into clinical practice, mostly in oncology. When designing epigenetic biomarkers, factors such as the identification of the best genomic regions, pre-analytical processing, accuracy of DNA methylation measurements, identification of confounding parameters, accreditation as a diagnostic procedure, standardized data analysis, turnaround time, and costs and customer requirements should be considered.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2022)

Review Cell Biology

Epigenetic age prediction

Daniel J. Simpson et al.

Summary: Advanced age is a common risk factor for cancer, cardiovascular disease, and neurodegeneration. Molecular research on aging has been slow due to unreliable tools for predicting biological age. The development of epigenetic clocks has provided a quantitative measure for studying biological aging.

AGING CELL (2021)

Review Genetics & Heredity

DNA Methylation Biomarkers in Aging and Age-Related Diseases

Yasmeen Salameh et al.

FRONTIERS IN GENETICS (2020)

Article Multidisciplinary Sciences

Targeted methods for epigenetic age predictions in mice

Yang Han et al.

SCIENTIFIC REPORTS (2020)

Review Biotechnology & Applied Microbiology

DNA methylation aging clocks: challenges and recommendations

Christopher G. Bell et al.

GENOME BIOLOGY (2019)

Article Cell Biology

An epigenetic biomarker of aging for lifespan and healthspan

Morgan E. Levine et al.

AGING-US (2018)

Article Cell Biology

A multi-tissue full lifespan epigenetic clock for mice

Michael J. Thompson et al.

AGING-US (2018)

Article Biology

A whole lifespan mouse multi-tissue DNA methylation clock

Margarita V. Meer et al.

Article Biotechnology & Applied Microbiology

Multi-tissue DNA methylation age predictor in mouse

Thomas M. Stubbs et al.

GENOME BIOLOGY (2017)

Article Cell Biology

Using DNA Methylation Profiling to Evaluate Biological Age and Longevity Interventions

Daniel A. Petkovich et al.

CELL METABOLISM (2017)

Article Biochemistry & Molecular Biology

ENmix: a novel background correction method for Illumina HumanMethylation450 BeadChip

Zongli Xu et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Biochemical Research Methods

RCP: a novel probe design bias correction method for Illumina Methylation BeadChip

Liang Niu et al.

BIOINFORMATICS (2016)

Article Biotechnology & Applied Microbiology

Quantitative comparison of DNA methylation assays for biomarker development and clinical applications

Christoph Bock et al.

NATURE BIOTECHNOLOGY (2016)

Article Biotechnology & Applied Microbiology

An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease

Steve Horvath et al.

GENOME BIOLOGY (2016)

Article Biotechnology & Applied Microbiology

DNA methylation age of blood predicts all-cause mortality in later life

Riccardo E. Marioni et al.

GENOME BIOLOGY (2015)

Article Biotechnology & Applied Microbiology

Aging of blood can be tracked by DNA methylation changes at just three CpG sites

Carola Ingrid Weidner et al.

GENOME BIOLOGY (2014)

Article Biotechnology & Applied Microbiology

Intergenerational genomic DNA methylation patterns in mouse hybrid strains

Luz D. Orozco et al.

GENOME BIOLOGY (2014)

Article Biochemistry & Molecular Biology

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

Gregory Hannum et al.

MOLECULAR CELL (2013)

Article Biotechnology & Applied Microbiology

DNA methylation age of human tissues and cell types

Steve Horvath

GENOME BIOLOGY (2013)

Article Cell Biology

Epigenetic-aging-signature to determine age in different tissues

Carmen M. Koch et al.

AGING-US (2011)

Article Biotechnology & Applied Microbiology

High density DNA methylation array with single CpG site resolution

Marina Bibikova et al.

GENOMICS (2011)

Article Multidisciplinary Sciences

Epigenetic Predictor of Age

Sven Bocklandt et al.

PLOS ONE (2011)

Article Multidisciplinary Sciences

Epigenetic differences arise during the lifetime of monozygotic twins

MF Fraga et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)