相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Blocking neddylation elicits antiviral effect against hepatitis B virus replication
Karima Abounouh et al.
MOLECULAR BIOLOGY REPORTS (2022)
Immunomodulatory effects of pevonedistat, a NEDD8-activating enzyme inhibitor, in chronic lymphocytic leukemia-derived T cells
Scott Best et al.
LEUKEMIA (2021)
Neddylation of PTEN regulates its nuclear import and promotes tumor development
Ping Xie et al.
CELL RESEARCH (2021)
Neddylation inhibitor MLN4924 has anti-HBV activity via modulating the ERK-HNF1α-C/EBPα-HNF4α axis
Mingjie Xie et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)
The E3 ubiquitin ligase Cul4b promotes CD4(+) T cell expansion by aiding the repair of damaged DNA
Asif A. Dar et al.
PLOS BIOLOGY (2021)
Neddylation pathway alleviates chronic pancreatitis by reducing HIF1α-CCL5-dependent macrophage infiltration
Yuli Lin et al.
CELL DEATH & DISEASE (2021)
RNF111-facilitated neddylation potentiates cGAS-mediated antiviral innate immune response
Chenhui Li et al.
PLOS PATHOGENS (2021)
Neddylation Alleviates Methicillin-Resistant Staphylococcus aureus Infection by Inducing Macrophage Reactive Oxygen Species Production
Huiqing Xiu et al.
JOURNAL OF IMMUNOLOGY (2021)
Myeloid neddylation targets IRF7 and promotes host innate immunity against RNA viruses
Min Zhao et al.
PLOS PATHOGENS (2021)
NEDD8 Deamidation Inhibits Cullin RING Ligase Dynamics
Priyesh Mohanty et al.
FRONTIERS IN IMMUNOLOGY (2021)
Inhibition of the Neddylation Pathway Suppresses Enterovirus Replication
Zhe Zhang et al.
VIROLOGICA SINICA (2021)
Neddylation Regulates Macrophages and Implications for Cancer Therapy
Yanyu Jiang et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Lipin-2 degradation elicits a proinflammatory gene signature in macrophages
Asami Watahiki et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)
Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer
Daniel J. McGrail et al.
CANCER CELL (2020)
Molecular mechanisms and cellular functions of cGAS-STING signalling
Karl-Peter Hopfner et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)
Neddylation of M1 negatively regulates the replication of influenza A virus
Yucen Li et al.
JOURNAL OF GENERAL VIROLOGY (2020)
Importance of Cullin4 Ubiquitin Ligase in Malignant Pleural Mesothelioma
Mayura Meerang et al.
CANCERS (2020)
Neddylation inhibition upregulates PD-L1 expression and enhances the efficacy of immune checkpoint blockade in glioblastoma
Shaolong Zhou et al.
INTERNATIONAL JOURNAL OF CANCER (2019)
Promotion of tumor-associated macrophages infiltration by elevated neddylation pathway via NF-kappa B-CCL2 signaling in lung cancer
Lisha Zhou et al.
ONCOGENE (2019)
Neddylation Facilitates the Antiviral Response in Zebrafish
Guangqing Yu et al.
FRONTIERS IN IMMUNOLOGY (2019)
Validation of NEDD8-conjugating enzyme UBC12 as a new therapeutic target in lung cancer
Lihui Li et al.
EBIOMEDICINE (2019)
Inhibiting neddylation modification alters mitochondrial morphology and reprograms energy metabolism in cancer cells
Qiyin Zhou et al.
JCI INSIGHT (2019)
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
Karen V. Swanson et al.
NATURE REVIEWS IMMUNOLOGY (2019)
MLN4924 suppresses lipopolysaccharide-induced proinflammatory cytokine production in neutrophils in a dose-dependent manner
Jiayang Jin et al.
ONCOLOGY LETTERS (2018)
Neddylation contributes to CD4(+) T cell-mediated protective immunity against blood-stage Plasmodium infection
Qianqian Cheng et al.
PLOS PATHOGENS (2018)
SAG/RBX2 E3 Ubiquitin Ligase Differentially Regulates Inflammatory Responses of Myeloid Cell Subsets
Xiufang Xiong et al.
FRONTIERS IN IMMUNOLOGY (2018)
Effects of the NEDD8-Activating Enzyme Inhibitor MLN4924 on Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus
Pey-Jium Chang et al.
JOURNAL OF VIROLOGY (2017)
HDM2 Promotes NEDDylation of Hepatitis B Virus HBx To Enhance Its Stability and Function
Ningning Liu et al.
JOURNAL OF VIROLOGY (2017)
Inhibition of Vpx-Mediated SAMHD1 and Vpr-Mediated Host Helicase Transcription Factor Degradation by Selective Disruption of Viral CRL4 (DCAF1) E3 Ubiquitin Ligase Assembly
Hong Wang et al.
JOURNAL OF VIROLOGY (2017)
Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo
Yaw Asare et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
NEDDylation of PB2 Reduces Its Stability and Blocks the Replication of Influenza A Virus
Tinghong Zhang et al.
SCIENTIFIC REPORTS (2017)
Therapeutic Effects of a NEDD8-Activating Enzyme Inhibitor, Pevonedistat, on Sclerodermatous Graft-versus-Host Disease in Mice
Chien-Chun Steven Pai et al.
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2017)
Neddylation is required for herpes simplex virus type I (HSV-1)-induced early phase interferon-beta production
Xueying Zhang et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2016)
SAG/Rbx2-Dependent Neddylation Regulates T-Cell Responses
Nathan D. Mathewson et al.
AMERICAN JOURNAL OF PATHOLOGY (2016)
MLN4924, a First-in-Class NEDD8-Activating Enzyme Inhibitor, Attenuates IFN-β Production
Hui Song et al.
JOURNAL OF IMMUNOLOGY (2016)
Neddylation requires glycyl-tRNA synthetase to protect activated E2
Zhongying Mo et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Neddylation requires glycyl-tRNA synthetase to protect activated E2
Zhongying Mo et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
MLN4924 sensitizes monocytes and maturing dendritic cells for TNF-dependent and -independent necroptosis
Mohamed El-Mesery et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
Protein neddylation: beyond cullin-RING ligases
Radoslav I. Enchev et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)
Suppressive role of neddylation in dendritic cells during Mycobacterium tuberculosis infection
Attinder Chadha et al.
TUBERCULOSIS (2015)
Targeting neddylation induces DNA damage and checkpoint activation and sensitizes chronic lymphocytic leukemia B cells to alkylating agents
C. Paiva et al.
CELL DEATH & DISEASE (2015)
NEDDylation Is Essential for Kaposi's Sarcoma- Associated Herpesvirus Latency and Lytic Reactivation and Represents a Novel Anti-KSHV Target
David J. Hughes et al.
PLOS PATHOGENS (2015)
The E3 Ubiquitin Ligase AMFR and INSIG1 Bridge the Activation of TBK1 Kinase by Modifying the Adaptor STING
Qiang Wang et al.
IMMUNITY (2014)
Neddylation pathway regulates the proliferation and survival of macrophages
Lihui Li et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Neddylation plays an important role in the regulation of murine and human dendritic cell function
Nathan Mathewson et al.
BLOOD (2013)
Neddylation pathway regulates T-cell function by targeting an adaptor protein Shc and a protein kinase Erk signaling
Hyung-seung Jin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
HIV relies on neddylation for ubiquitin ligase-mediated functions
Michael D. Nekorchuk et al.
RETROVIROLOGY (2013)
Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects
Xiao-Dong Li et al.
SCIENCE (2013)
Neutrophil recruitment and function in health and inflammation
Elzbieta Kolaczkowska et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Suppression of Dendritic Cell-mediated Responses by Genes in Calcium and Cysteine Protease Pathways during Mycobacterium tuberculosis Infection
Jhalak Singhal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis
Qing Yao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis
Y. Zhao et al.
CELL DEATH & DISEASE (2012)
Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G
David J. Stanley et al.
PLOS PATHOGENS (2012)
Global Identification of Modular Cullin-RING Ligase Substrates
Michael J. Emanuele et al.
CELL (2011)
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
Teresa A. Soucy et al.
NATURE (2009)
Novel substrates and functions for the ubiquitin-like molecule NEDD8
Dimitris P. Xirodimas
BIOCHEMICAL SOCIETY TRANSACTIONS (2008)
Structural insights into NEDD8 activation of Cullin-RING ligases: Conformational control of conjugation
David M. Duda et al.
CELL (2008)
Function and regulation of protein neddylation - 'Protein Modifications: Beyond the Usual Suspects' review series
Gwenael Rabut et al.
EMBO REPORTS (2008)
Involvement of the IκB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation
Annie Bibeau-Poirier et al.
JOURNAL OF IMMUNOLOGY (2006)
Neddylation of a breast cancer-associated protein recruits a class III histone deacetylase that represses NFκB-dependent transcription
Fei Gao et al.
NATURE CELL BIOLOGY (2006)
p53 ubiquitination: Mdm2 and beyond
CL Brooks et al.
MOLECULAR CELL (2006)
Ubiquitin-like protein activation
DT Huang et al.
ONCOGENE (2004)