4.8 Article

Biofilm-inspired Amyloid-Polysaccharide Composite Materials

期刊

APPLIED MATERIALS TODAY
卷 27, 期 -, 页码 -

出版社

ELSEVIER
DOI: 10.1016/j.apmt.2022.101497

关键词

-

资金

  1. National Key R&D Program of China [2018YFA0902804]
  2. National Natural Science Foundation of China [U1932204]
  3. Center for High-resolution Electron Microscopy (ChEM) at ShanghaiTech University

向作者/读者索取更多资源

This study successfully created a new functional hybrid material by mimicking the structure of bacterial biofilms and using amyloid-polysaccharide composite matrix. The material combines the toughness of polysaccharide fibers and the functionality of amyloid fusion proteins, allowing it to interact with inorganic materials and be potentially applied in electronics and organic-inorganic interfaces. Additionally, it offers a potential alternative to industrial polymers or plastics with its low-cost and environmentally-friendly nature.
Natural materials can inspire the design of functional structures and sustainable materials. Bacterial biofilms formed by polymicrobial cultures typically comprise a robust interwoven fibrous network made of proteins and exopolysaccharides, protecting the cells trapped inside against various environmental stressors. Inspired by these structures, we report an amyloid-polysaccharide composite matrix using the building block of Escherichia coli biofilms (CsgA) and chitin, the second most abundant polysaccharide. We chose these two substances to mimic the main components of biofilms and combine the toughness of polysaccharide fibers and the functionality of amyloid fusion proteins to produce a new functional hybrid material. Due to the chitin-binding domain and other functional tags, the chitin-amyloid composite matrix exhibited good molecular interaction and functionality, which formed a coating on the material surface and was made into a freestanding film. With the help of this composite coating, we adhered inorganic materials onto various material surfaces. The ability to interact with inorganic materials allows this new material to be applied to electronics and organic-inorganic interfaces, and the freestanding films provide an opportunity for fabricating intelligent materials or wearable electronic devices. Additionally, these biopolymer ingredients may offer a low-cost and environmentally-friendly bio-based alternative to industrial polymers or plastics in consumer products.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据