4.7 Article

Heterogeneity in extracellular vesicle secretion by single human macrophages revealed by super-resolution microscopy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Microscopy approaches to study extracellular vesicles

Federico Colombo et al.

Summary: EVs have drawn attention for their role in cell-to-cell communication and diagnostic potential. Recent advances in microscopy have allowed for more precise study of EV molecular composition. Careful experimental planning is crucial for choosing the right techniques for specific research questions.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2021)

Article Pharmacology & Pharmacy

The human G protein-coupled ATP receptor P2Y11 is a target for anti-inflammatory strategies

Georg Gruenbacher et al.

Summary: The study used transcriptome and secretome profiling to analyze the signaling and function of ectopic P2Y(11) receptors, which were validated in human monocyte-derived M2 macrophages. The results showed that targeting P2Y(11) receptors can activate IL-1 receptor signaling to promote sTNFR2 release and suppress TLR4 signaling, facilitating resolution of inflammation.

BRITISH JOURNAL OF PHARMACOLOGY (2021)

Article Cell Biology

Single-vesicle imaging and co-localization analysis for tetraspanin profiling of individual extracellular vesicles

Chungmin Han et al.

Summary: This study introduces a single vesicle analysis method that visualizes marker expressions of individual EVs and investigates their subpopulations. The analysis successfully illustrated the diversity of EVs and revealed distinct patterns of tetraspanin expressions. Application of the analysis demonstrated similarities and dissimilarities between EV fractions acquired from different conventional isolation methods.

JOURNAL OF EXTRACELLULAR VESICLES (2021)

Article Oncology

Junctional Adhesion Molecule-Like Protein Promotes Tumor Progression and Metastasis via p38 Signaling Pathway in Gastric Cancer

Yuying Fang et al.

Summary: JAML, a newly discovered junctional adhesion molecule, plays a critical role in promoting gastric cancer cell migration and proliferation, potentially serving as a novel diagnostic biomarker and therapeutic target for gastric cancer.

FRONTIERS IN ONCOLOGY (2021)

Review Biochemical Research Methods

The power of imaging to understand extracellular vesicle biology in vivo

Frederik J. Verweij et al.

Summary: Extracellular vesicles (EVs) are nano-sized lipid bilayer vesicles released by virtually every cell type, with diverse biological activities. Recent advances in live and high-resolution microscopy techniques, combined with innovative EV labeling strategies, provide new tools to study EVs in vivo at the single-vesicle level.

NATURE METHODS (2021)

Article Multidisciplinary Sciences

Identifying extracellular vesicle populations from single cells

Jonas M. Nikoloff et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

Article Cell Biology

Purity and yield of melanoma exosomes are dependent on isolation method

Shin La Shu et al.

JOURNAL OF EXTRACELLULAR VESICLES (2020)

Review Cell Biology

Inhibiting extracellular vesicles formation and release: a review of EV inhibitors

Mariadelva Catalano et al.

JOURNAL OF EXTRACELLULAR VESICLES (2020)

Article Multidisciplinary Sciences

Synaptic secretion from human natural killer cells is diverse and includes supramolecular attack particles

Ashley R. Ambrose et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Multidisciplinary Sciences

Multiplexed profiling of single-cell extracellular vesicles secretion

Yahui Ji et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Biochemistry & Molecular Biology

The biology of extracellular vesicles: The known unknowns

Leonid Margolis et al.

PLOS BIOLOGY (2019)

Article Multidisciplinary Sciences

Assessing the role of surface glycans of extracellular vesicles on cellular uptake

Charles Williams et al.

SCIENTIFIC REPORTS (2019)

Article Cell Biology

Single molecule characterization of individual extracellular vesicles from pancreatic cancer

Kathleen M. Lennon et al.

JOURNAL OF EXTRACELLULAR VESICLES (2019)

Review Cell Biology

M2b macrophage polarization and its roles in diseases

Le-xun Wang et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2019)

Article Biochemistry & Molecular Biology

Nanoscale Dynamism of Actin Enables Secretory Function in Cytolytic Cells

Alexandre F. Carisey et al.

CURRENT BIOLOGY (2018)

Article Biochemical Research Methods

Quantitative mapping and minimization of super-resolution optical imaging artifacts

Sian Culley et al.

NATURE METHODS (2018)

Article Biochemistry & Molecular Biology

Rapid and accurate analysis of stem cell-derived extracellular vesicles with super resolution microscopy and live imaging

Zubair Nizamudeen et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2018)

Review Biochemistry & Molecular Biology

Macrophage Phenotypes Regulate Scar Formation and Chronic Wound Healing

Mark Hesketh et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Multidisciplinary Sciences

Image based Machine Learning for identification of macrophage subsets

Hassan M. Rostam et al.

SCIENTIFIC REPORTS (2017)

Article Biochemistry & Molecular Biology

Qualitative differences in T-cell activation by dendritic cell-derived extracellular vesicle subtypes

Mercedes Tkach et al.

EMBO JOURNAL (2017)

Article Respiratory System

Alveolar macrophage-derived microvesicles mediate acute lung injury

Sanooj Soni et al.

THORAX (2016)

Review Immunology

Comparative Anatomy of Phagocytic and immunological Synapses

Florence Niedergang et al.

FRONTIERS IN IMMUNOLOGY (2016)

Article Multidisciplinary Sciences

Regulated delivery of molecular cargo to invasive tumour-derived microvesicles

James W. Clancy et al.

NATURE COMMUNICATIONS (2015)

Article Multidisciplinary Sciences

Cambinol, a Novel Inhibitor of Neutral Sphingomyelinase 2 Shows Neuroprotective Properties

Mariana Figuera-Losada et al.

PLOS ONE (2015)

Review Immunology

The ins and outs of MHC class II-mediated antigen processing and presentation

Paul A. Roche et al.

NATURE REVIEWS IMMUNOLOGY (2015)

Review Immunology

Tissue macrophage identity and self-renewal

Rebecca Gentek et al.

IMMUNOLOGICAL REVIEWS (2014)

Article Endocrinology & Metabolism

Lipocalin 2 is a Regulator Of Macrophage Polarization and NF-κB/STAT3 Pathway Activation

Hong Guo et al.

MOLECULAR ENDOCRINOLOGY (2014)

Article Multidisciplinary Sciences

Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse

Kaushik Choudhuri et al.

NATURE (2014)

Review Endocrinology & Metabolism

Extracellular vesicles as an emerging mechanism of cell-to-cell communication

Ciro Tetta et al.

ENDOCRINE (2013)

Article Biochemistry & Molecular Biology

LAPTM5 Protein Is a Positive Regulator of Proinflammatory Signaling Pathways in Macrophages

Wioletta K. Glowacka et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Biochemical Research Methods

Fiji: an open-source platform for biological-image analysis

Johannes Schindelin et al.

NATURE METHODS (2012)

Article Cell Biology

Receptor mobility, the cytoskeleton, and particle binding during phagocytosis

Valentin Jaumouille et al.

CURRENT OPINION IN CELL BIOLOGY (2011)

Article Multidisciplinary Sciences

Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'

Helen S. Goodridge et al.

NATURE (2011)

Article Biochemistry & Molecular Biology

Natural Killer Cell Lytic Granule Secretion Occurs through a Pervasive Actin Network at the Immune Synapse

Gregory D. Rak et al.

PLOS BIOLOGY (2011)

Article Hematology

Activated T cells recruit exosomes secreted by dendritic cells via LFA-1

Esther N. M. Nolte-'t Hoen et al.

Article Multidisciplinary Sciences

Ceramide triggers budding of exosome vesicles into multivesicular Endosomes

Katarina Trajkovic et al.

SCIENCE (2008)

Article Biochemical Research Methods

Semi-supervised learning for peptide identification from shotgun proteomics datasets

Lukas Kall et al.

NATURE METHODS (2007)

Article Immunology

CD8+ dendritic cells use LFA-1 to capture MHC-peptide complexes from exosomes in vivo

Elodie Segura et al.

JOURNAL OF IMMUNOLOGY (2007)