Nanofat and Platelet-Rich Plasma injections used in a case of severe acne scars

Background: Acne is a common chronic inflammatory disease, which can result in permanent scarring. Differ-ent types of treatments have been used in order to treat acne scars. However, esthetic results have proved variable. Furthermore, none of these treatments has had an impact on the underlying inflammatory process. Objective: The main purpose of this case-report is to suggest a new potential therapy for acne scar manage-ment combining esthetic filling with an anti-inflammatory and a regenerative action. Methods: A Platelet rich plasma (PRP) and Nanofat mixture was injected into the pathological dermis in order to treat and fill severe acne scars. Results: After a one-year follow-up, skin elasticity had improved, scar reduction and a reversal of the inflam-mation process had been observed. Conclusions: PRP and Nanofat could represent a new and promising therapeutic approach in the treatment of the inflammatory scarring process in severe acne. (c) 2022 Elsevier Masson SAS. All rights reserved.

Automated summary

This article introduces a new treatment method that combines esthetic filling, anti-inflammatory, and regenerative actions. It involves injecting a mixture of platelet-rich plasma (PRP) and nanofat into severe acne scars. After one year of follow-up, improvements in skin elasticity, scar reduction, and a reversal of the inflammatory process were observed.