相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Proof-of-Concept of Continuous Transfection for Adeno-Associated Virus Production in Microcarrier-Based Culture
Brian Ladd et al.
PROCESSES (2022)
Selective endocytosis of recombinant human BMPs through cell surface heparan sulfate proteoglycans in CHO cells: BMP-2 and BMP-7
Mi Gyeom Kim et al.
SCIENTIFIC REPORTS (2021)
A systematic review of SARS-CoV-2 vaccine candidates
Yetian Dong et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)
Mammalian cell culture for production of recombinant proteins: A review of the critical steps in their biomanufacturing
Roisin O'Flaherty et al.
BIOTECHNOLOGY ADVANCES (2020)
Improving recombinant bone morphogenetic protein-4 (BMP-4) production by autoregulatory feedback loop removal using BMP receptor-knockout CHO cell lines
Che Lin Kim et al.
METABOLIC ENGINEERING (2019)
Recombinant Proteins for Industrial versus Pharmaceutical Purposes: A Review of Process and Pricing
John Puetz et al.
PROCESSES (2019)
High cell density transient transfection of CHO cells for TGF-β1 expression
Abdalla A. Elshereef et al.
ENGINEERING IN LIFE SCIENCES (2019)
In Vitro Evaluation of Recombinant Bone Morphogenetic Protein-2 Bioactivity for Regenerative Medicine
Stephanie L. Fung et al.
TISSUE ENGINEERING PART C-METHODS (2019)
BMP-2 Gene Delivery-Based Bone Regeneration in Dentistry
Shin-Young Park et al.
PHARMACEUTICS (2019)
Structural determinants and genetic modifications enhance BMP2 stability and extracellular secretion
Vinayak Khattar et al.
FASEB BIOADVANCES (2019)
Modifying inter-cistronic sequence significantly enhances IRES dependent second gene expression in bicistronic vector: Construction of optimised cassette for gene therapy of familial hypercholesterolemia
Faisal A. Al-Allaf et al.
NON-CODING RNA RESEARCH (2019)
Improving the production of recombinant human bone morphogenetic protein-4 in Chinese hamster ovary cell cultures by inhibition of undesirable endocytosis
Che Lin Kim et al.
BIOTECHNOLOGY AND BIOENGINEERING (2018)
Advancements in mammalian cell transient gene expression (TGE) technology for accelerated production of biologics
Sonia Gutierrez-Granados et al.
CRITICAL REVIEWS IN BIOTECHNOLOGY (2018)
Comparison of cell-based versus cell-free mammalian systems for the production of a recombinant human bone morphogenic growth factor
Valerie Jerome et al.
ENGINEERING IN LIFE SCIENCES (2017)
Therapeutic glycoprotein production in mammalian cells
Marie-Eve Lalonde et al.
JOURNAL OF BIOTECHNOLOGY (2017)
Cloning of CHO Cells, Productivity and Genetic Stability-A Discussion
Florian M. Wurm et al.
PROCESSES (2017)
BMP-2-induced bone formation and neural inflammation
Vi Nguyen et al.
JOURNAL OF ORTHOPAEDICS (2017)
Comparison of Three Transposons for the Generation of Highly Productive Recombinant CHO Cell Pools and Cell Lines
Sowmya Balasubramanian et al.
BIOTECHNOLOGY AND BIOENGINEERING (2016)
Heparan sulfate proteoglycan synthesis in CHO DG44 and HEK293 cells
Sojeong Lee et al.
BIOTECHNOLOGY AND BIOPROCESS ENGINEERING (2016)
BMPs in bone regeneration: Less is more effective, a paradigm-shift
Katharina Schmidt-Bleek et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2016)
Alleviation of proteolytic degradation of recombinant human bone morphogenetic protein-4 by repeated batch culture of Chinese hamster ovary cells
Che Lin Kim et al.
PROCESS BIOCHEMISTRY (2016)
Bone Morphogenetic Proteins
Takenobu Katagiri et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)
Extended Gene Expression by Medium Exchange and Repeated Transient Transfection for Recombinant Protein Production Enhancement
Laura Cervera et al.
BIOTECHNOLOGY AND BIOENGINEERING (2015)
A High Cell Density Transient Transfection System for Therapeutic Protein Expression Based on a CHO GS-Knockout Cell Line: Process Development and Product Quality Assessment
Yashas Rajendra et al.
BIOTECHNOLOGY AND BIOENGINEERING (2015)
Asparagine-linked glycosylation of bone morphogenetic protein-2 is required for secretion and osteoblast differentiation
Qinglei Hang et al.
GLYCOBIOLOGY (2014)
Bone Morphogenetic Proteins Facts, Challenges, and Future Perspectives
A. C. Carreira et al.
JOURNAL OF DENTAL RESEARCH (2014)
Over-expression of secreted proteins from mammalian cell lines
Annamarie C. Dalton et al.
PROTEIN SCIENCE (2014)
Quantitative kinetics analysis of BMP2 uptake into cells and its modulation by BMP antagonists
Hamed Alborzinia et al.
JOURNAL OF CELL SCIENCE (2013)
Polyethyleneimine-based transient gene expression processes for suspension-adapted HEK-293E and CHO-DG44 cells
David L. Hacker et al.
PROTEIN EXPRESSION AND PURIFICATION (2013)
Role of non-specific DNA in reducing coding DNA requirement for transient gene expression with CHO and HEK-293E cells
Yashas Rajendra et al.
BIOTECHNOLOGY AND BIOENGINEERING (2012)
Polyarginine peptide IND-1 enhances recombinant human bone morphogenetic protein-2 yield in mammalian cells
Aileen J. Zhou et al.
BIOTECHNOLOGY LETTERS (2012)
Effect of Bone Morphogenetic Protein-2 on Proliferation and Apoptosis of Gastric Cancer Cells
Junjie Zhang et al.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2012)
Critical assessment of rhBMP-2 mediated bone induction: An in vitro and in vivo evaluation
Marta Kisiel et al.
JOURNAL OF CONTROLLED RELEASE (2012)
Use and efficacy of bone morphogenetic proteins in fracture healing
Suzanne N. Lissenberg-Thunnissen et al.
INTERNATIONAL ORTHOPAEDICS (2011)
A simple high-yielding process for transient gene expression in CHO cells
Yashas Rajendra et al.
JOURNAL OF BIOTECHNOLOGY (2011)
A simplified polyethylenimine-mediated transfection process for large-scale and high-throughput applications
Celine Raymond et al.
METHODS (2011)
Investigating Bone Morphogenetic Protein (BMP) Signaling in a Newly Established Human Cell Line Expressing BMP Receptor Type II
Tada-aki Kudo et al.
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Reflections on more than 10 years of TGE approaches
Sabine Geisse
PROTEIN EXPRESSION AND PURIFICATION (2009)
Rational vector design and multi-pathway modulation of HEK 293E cells yield recombinant antibody titers exceeding 1 g/l by transient transfection under serum-free conditions
Gaurav Backliwal et al.
NUCLEIC ACIDS RESEARCH (2008)
High-density transfection with HEK-293 cells allows doubling of transient titers and removes need for a priori DNA complex formation with PEI
Gaurav Backliwal et al.
BIOTECHNOLOGY AND BIOENGINEERING (2008)
Recombinant protein production by large-scale transient gene expression in mammalian cells: state of the art and future perspectives
Lucia Baldi et al.
BIOTECHNOLOGY LETTERS (2007)
Transient gene expression in suspension HEK-293 cells: Application to large-scale protein production
L Baldi et al.
BIOTECHNOLOGY PROGRESS (2005)
Balancing GFP reporter plasmid quantity in large-scale transient transfections for recombinant anti-human rhesus-D IgG1 synthesis
HM Pick et al.
BIOTECHNOLOGY AND BIOENGINEERING (2002)