期刊
OPEN FORUM INFECTIOUS DISEASES
卷 9, 期 7, 页码 -出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/ofid/ofac211
关键词
cryptococcosis; glucuronoxylomannan; IgM; laminarin; transplant recipients
资金
- National Institutes of Health [R01 AI143453]
This study investigated the relationship between antibody immunity and cryptococcosis in organ transplant recipients. It found that specific antibody levels may serve as markers for cryptococcosis.
Antibody immunity has not been studied in organ transplant recipients (OTRs) with cryptococcosis. We determined serum antibody levels in OTRs: 23 cryptococcosis cases and 21 controls. Glucuronoxylomannan immunoglobulin M (IgM) and laminarin IgM were lower in cases than controls, were inversely associated with cryptococcosis status, and may hold promise as markers of cryptococcosis.
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