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IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation
RM McLoughlin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Identification of a genetic signature of activated signal transducer and activator of transcription 3 in human tumors
JV Alvarez et al.
CANCER RESEARCH (2005)
A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells
H Song et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Tumour necrosis factor-alpha, interleukin-6, and fasting serum insulin correlate with clinical outcome in metastatic breast cancer patients treated with chemotherapy
H Bozcuk et al.
CYTOKINE (2004)
Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C
TN Dechow et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells
TH Wang et al.
NATURE MEDICINE (2004)
Serum levels of IL-6 and TNF-α correlate with clinicopathological features and patient survival in patients with prostate cancer
V Michalaki et al.
BRITISH JOURNAL OF CANCER (2004)
Serum interleukin-6 levels reflect the disease status of colorectal cancer
YC Chung et al.
JOURNAL OF SURGICAL ONCOLOGY (2003)
Hexameric structure and assembly of the interleukin-6/IL-6 α-receptor/gp130 complex
MJ Boulanger et al.
SCIENCE (2003)
Interleukin-6 differentially regulates androgen receptor transactivation via PI3K-Akt, STAT3, and MAPK, three distinct signal pathways in prostate cancer cells
L Yang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Prognostic value of serum levels of interleukin 6 and of serum and plasma levels of vascular endothelial growth factor in hormone-refractory metastatic breast cancer patients
T Bachelot et al.
BRITISH JOURNAL OF CANCER (2003)
Circulating interleukin-6 predicts survival in patients with metastatic breast cancer
R Salgado et al.
INTERNATIONAL JOURNAL OF CANCER (2003)
Suppressors of cytokine signaling and immunity
M Kubo et al.
NATURE IMMUNOLOGY (2003)
Anti-interleukin 6 (IL-6) receptor antibody suppresses Castleman's disease like symptoms emerged in IL-6 transgenic mice
A Katsume et al.
CYTOKINE (2002)
Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells
PJ Real et al.
ONCOGENE (2002)
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis
GL Niu et al.
ONCOGENE (2002)
Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells
WM Burke et al.
ONCOGENE (2001)
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
T Sorlie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.
DJ Slamon et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses
T Jostock et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2001)
Molecular portraits of human breast tumours
CM Perou et al.
NATURE (2000)
Reduction in serum IL-6 after vacination of breast cancer patients with tumour-associated antigens is related to estrogen receptor status
XP Jiang et al.
CYTOKINE (2000)