4.6 Article

Molecular Biomarker of Drug Resistance Developed From Patient-Derived Organoids Predicts Survival of Colorectal Cancer Patients

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Identification of a prognostic gene signature of colon cancer using integrated bioinformatics analysis

Zhengyu Fang et al.

Summary: This study aimed to construct a prognostic model for predicting the prognosis of colon cancer using gene expression data. The 12-gene signature prognostic model showed high predictive ability for the prognosis of colon cancer, with significant association with clinical factors in patients.

WORLD JOURNAL OF SURGICAL ONCOLOGY (2021)

Article Multidisciplinary Sciences

A 14-gene gemcitabine resistance gene signature is significantly associated with the prognosis of pancreatic cancer patients

Xing Wei et al.

Summary: A 14-gene signature associated with gemcitabine resistance was identified in pancreatic cancer, which was validated to be a poor prognostic indicator in multiple independent cohorts. The signature also served as an independent predictor of pancreatic cancer outcomes in different datasets and a nomogram was established for clinical translation.

SCIENTIFIC REPORTS (2021)

Review Oncology

Biomarker-guided therapy for colorectal cancer: strength in complexity

Anita Sveen et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2020)

Review Pharmacology & Pharmacy

5-fluorouracil and other fluoropyrimidines in colorectal cancer: Past, present and future

Sona Vodenkova et al.

PHARMACOLOGY & THERAPEUTICS (2020)

Article Cell Biology

SEZ6L2 knockdown impairs tumour growth by promoting caspase-dependent apoptosis in colorectal cancer

Ning An et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)

Review Medicine, General & Internal

Organoids - Preclinical Models of Human Disease

Mo Li et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Oncology

TGF-β1 protects colon tumor cells from apoptosis through XAF1 suppression

Jung Rock Moon et al.

INTERNATIONAL JOURNAL OF ONCOLOGY (2019)

Review Multidisciplinary Sciences

Translational genomics and precision medicine: Moving from the lab to the clinic

Eleftheria Zeggini et al.

SCIENCE (2019)

Review Medicine, General & Internal

Colorectal cancer

Evelien Dekker et al.

LANCET (2019)

Article Biochemistry & Molecular Biology

A rectal cancer organoid platform to study individual responses to chemoradiation

Karuna Ganesh et al.

NATURE MEDICINE (2019)

Article Oncology

ITGB4 is a novel prognostic factor in colon cancer

Meng Li et al.

JOURNAL OF CANCER (2019)

Article Biochemistry & Molecular Biology

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

Norman Sachs et al.

Article Multidisciplinary Sciences

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

Georgios Vlachogiannis et al.

SCIENCE (2018)

Review Oncology

Organoids in cancer research

Jarno Drost et al.

NATURE REVIEWS CANCER (2018)

Article Biochemistry & Molecular Biology

Human primary liver cancer-derived organoid cultures for disease modeling and drug screening

Laura Broutier et al.

NATURE MEDICINE (2017)

Article Oncology

Colorectal cancer statistics, 2017

Rebecca L. Siegel et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2017)

Article Biochemistry & Molecular Biology

TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data

Antonio Colaprico et al.

NUCLEIC ACIDS RESEARCH (2016)

Editorial Material Oncology

DNA-Guided Precision Medicine for Cancer: A Case of Irrational Exuberance?

Emile E. Voest et al.

CANCER DISCOVERY (2016)

Review Gastroenterology & Hepatology

The biological complexity of colorectal cancer: insights into biomarkers for early detection and personalized care

Marina De Rosa et al.

THERAPEUTIC ADVANCES IN GASTROENTEROLOGY (2016)

Article Biochemistry & Molecular Biology

Profilin 2 promotes migration, invasion, and stemness of HT29 human colorectal cancer stem cells

Min-Jung Kim et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2015)

Article Biochemistry & Molecular Biology

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

Marc van de Wetering et al.

Review Multidisciplinary Sciences

Building the foundation for genomics in precision medicine

Samuel J. Aronson et al.

NATURE (2015)

Article Multidisciplinary Sciences

TP53 loss creates therapeutic vulnerability in colorectal cancer

Yunhua Liu et al.

NATURE (2015)

Article Biochemistry & Molecular Biology

limma powers differential expression analyses for RNA-sequencing and microarray studies

Matthew E. Ritchie et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Oncology

Genetics, diagnosis and management of colorectal cancer

Marina De Rosa et al.

ONCOLOGY REPORTS (2015)

Article Genetics & Heredity

Gene signatures of drug resistance predict patient survival in colorectal cancer

Y. Zheng et al.

PHARMACOGENOMICS JOURNAL (2015)

Article Oncology

Overcoming 5-Fu Resistance of Colon Cells through Inhibition of Glut1 by the Specific Inhibitor WZB117

Wei Liu et al.

ASIAN PACIFIC JOURNAL OF CANCER PREVENTION (2014)

Article Oncology

Comparison of Tumor Regression Grade Systems for Locally Advanced Rectal Cancer After Multimodality Treatment

Atthaphorn Trakarnsanga et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2014)

Article Gastroenterology & Hepatology

Colon and Rectal Cancer Survival by Tumor Location and Microsatellite Instability: The Colon Cancer Family Registry

Amanda I. Phipps et al.

DISEASES OF THE COLON & RECTUM (2013)

Article Multidisciplinary Sciences

Comprehensive molecular characterization of human colon and rectal cancer

Donna M. Muzny et al.

NATURE (2012)

Article Biotechnology & Applied Microbiology

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

Guangchuang Yu et al.

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2012)

Article Multidisciplinary Sciences

Clinical Value of Prognosis Gene Expression Signatures in Colorectal Cancer: A Systematic Review

Rebeca Sanz-Pamplona et al.

PLOS ONE (2012)

Article Mathematical & Computational Biology

Purposeful selection of variables in logistic regression

Zoran Bursac et al.

SOURCE CODE FOR BIOLOGY AND MEDICINE (2008)

Article Public, Environmental & Occupational Health

Relaxing the rule of ten events per variable in logistic and Cox regression

Eric Vittinghoff et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2007)

Article Biochemistry & Molecular Biology

Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery

Paula M. De Angelis et al.

MOLECULAR CANCER (2006)

Article Multidisciplinary Sciences

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

A Subramanian et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Medicine, General & Internal

Preoperative versus postoperative chemoradiotherapy for rectal cancer

R Sauer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)