相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Proteolysis targeting chimera (PROTAC) in drug discovery paradigm: Recent progress and future challenges
Shenxin Zeng et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
Exploring the clinical value of tumor microenvironment in platinum-resistant ovarian cancer
Alia Ghoneum et al.
SEMINARS IN CANCER BIOLOGY (2021)
Abnormal expression of FAK and paxillin correlates with oral cancer invasion and metastasis
Ming Song et al.
ACTA BIOCHIMICA POLONICA (2021)
FAK inhibition alone or in combination with adjuvant therapies reduces cancer stem cell activity
Simon Timbrell et al.
NPJ BREAST CANCER (2021)
A Luminacin D Analog HL142 Inhibits Ovarian Tumor Growth and Metastasis by Reversing EMT and Attenuating the TGFβ and FAK Pathways
Baojin Wang et al.
JOURNAL OF CANCER (2021)
Degradation of proteins by PROTACs and other strategies
Yang Wang et al.
ACTA PHARMACEUTICA SINICA B (2020)
Phase 2 study of the focal adhesion kinase inhibitor defactinib (VS-6063) in previously treated advanced KRAS mutant non-small cell lung cancer
David E. Gerber et al.
LUNG CANCER (2020)
FAK-targeted and combination therapies for the treatment of cancer: an overview of phase I and II clinical trials
Atish Mohanty et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2020)
Expression of ASAP1 and FAK in gastric cancer and its clinicopathological significance
Qiong Luo et al.
ONCOLOGY LETTERS (2020)
A Chemical Switch System to Modulate Chimeric Antigen Receptor T Cell Activity through Proteolysis-Targeting Chimaera Technology
So Myoung Lee et al.
ACS SYNTHETIC BIOLOGY (2020)
High expression of AMAP1, an ARF6 effector, is associated with elevated levels of PD-L1 and fibrosis of pancreatic cancer
Akio Tsutaho et al.
CELL COMMUNICATION AND SIGNALING (2020)
PROTACs: An Emerging Therapeutic Modality in Precision Medicine
Dhanusha A. Nalawansha et al.
CELL CHEMICAL BIOLOGY (2020)
Novel immunomodulatory drugs and neo-substrates
Shaobing Gao et al.
BIOMARKER RESEARCH (2020)
A therapeutic patent overview of MDM2/X-targeted therapies (2014-2018)
Lukasz Skalniak et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2019)
Emerging drug development technologies targeting ubiquitination for cancer therapeutics
Gianluca Veggiani et al.
PHARMACOLOGY & THERAPEUTICS (2019)
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy
Carlos J. Diaz Osterman et al.
ELIFE (2019)
Large Chromosomal Rearrangements Yield Biomarkers to Distinguish Low-Risk From Inter mediate- and High-Risk Prostate Cancer
George Vasmatzis et al.
MAYO CLINIC PROCEEDINGS (2019)
The diacylglycerol kinase α (DGKα)/Akt/NF-κB feedforward loop promotes esophageal squamous cell carcinoma (ESCC) progression via FAK-dependent and FAK-independent manner
Jie Chen et al.
ONCOGENE (2019)
FAK-ERK activation in cell/matrix adhesion induced by the loss of apolipoprotein E stimulates the malignant progression of ovarian cancer
Huiling Lai et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
Lentiviral vector mediated-ASAP1 expression promotes epithelial to mesenchymal transition in ovarian cancer cells
Tao Zhang et al.
ONCOLOGY LETTERS (2018)
Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation
Philipp M. Cromm et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)
A Panel of Genes Identified as Targets for 8q24.13-24.3 Gain Contributing to Unfavorable Overall Survival in Patients with Hepatocellular Carcinoma
Kun Zhao et al.
CURRENT MEDICAL SCIENCE (2018)
Lentiviral CRISPR/Cas9 nickase vector mediated BIRC5 editing inhibits epithelial to mesenchymal transition in ovarian cancer cells
Guannan Zhao et al.
ONCOTARGET (2017)
A phase I, pharmacokinetic and pharmacodynamic study of GSK2256098, a focal adhesion kinase inhibitor, in patients with advanced solid tumors
J. C. Soria et al.
ANNALS OF ONCOLOGY (2016)
RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy- and 20,23-dihydroxyvitamin D
Andrzej T. Slominski et al.
FASEB JOURNAL (2014)
FAK Inhibition Disrupts a β5 Integrin Signaling Axis Controlling Anchorage-Independent Ovarian Carcinoma Growth
Isabelle Tancioni et al.
MOLECULAR CANCER THERAPEUTICS (2014)
Doxycycline Inducible Kruppel-Like Factor 4 Lentiviral Vector Mediates Mesenchymal to Epithelial Transition in Ovarian Cancer Cells
Zixuan Chen et al.
PLOS ONE (2014)
Inhibition of focal adhesion kinase (FAK) activity prevents anchorage-independent ovarian carcinoma cell growth and tumor progression
Kristy K. Ward et al.
CLINICAL & EXPERIMENTAL METASTASIS (2013)
CCR9 interactions support ovarian cancer cell survival and resistance to cisplatin-induced apoptosis in a PI3K-dependent and FAK-independent fashion
Erica L. Johnson et al.
JOURNAL OF OVARIAN RESEARCH (2010)
ASAP1, a gene at 8q24, is associated with prostate cancer metastasis
Dong Lin et al.
CANCER RESEARCH (2008)
Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation
Ssang-Taek Lim et al.
MOLECULAR CELL (2008)
Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53
VM Golubovskaya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
DDEF1 is located in an amplified region of chromosome 8q and is overexpressed in uveal melanoma
JP Ehlers et al.
CLINICAL CANCER RESEARCH (2005)
The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly
YH Liu et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
分享论文
