4.6 Review

Melanoma, Melanin, and Melanogenesis: The Yin and Yang Relationship

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Physics, Atomic, Molecular & Chemical

Interaction of Melanin with Metal Ions Modulates Their Cytotoxic Potential

Tadeusz Sarna et al.

Summary: Melanin, a common biological pigment, plays a crucial role in protecting the skin from damage caused by solar radiation and may also have antioxidative functions. It can sequester metal ions and scavenge reactive oxygen species, but under specific conditions, metal ions like iron and copper may induce cytotoxicity by facilitating their redox activation and release from melanin. The paper emphasizes the importance of EPR spectroscopy and other physicochemical methods in studying melanin.

APPLIED MAGNETIC RESONANCE (2022)

Article Biology

The biology of human hair greying

James D. B. O'Sullivan et al.

Summary: Hair greying is a complex process influenced by various factors including genetics, oxidative damage, and melanocyte senescence. The decline in melanogenesis is a key event in the initiation of greying, eventually leading to irreversible loss of melanocytes in the hair follicle. The role of genetic contributions and oxidative damage in driving greying remains unclear, and further research is needed to understand how factors such as hormonal regulation and psychosocial stress affect the process.

BIOLOGICAL REVIEWS (2021)

Article Plant Sciences

Plastid role in phytomelanin synthesis in Piptocarpha axillaris (Less.) Baker stems (Asteraceae, Vernonieae)

Josiane Wolff Coutinho et al.

Summary: Phytomelanin is a brown to black pigment found in plant tissues, mainly in Asparagales and Asteraceae species. Previous studies have shown that sclereids may be involved in the synthesis of phytomelanin.

PROTOPLASMA (2021)

Article Plant Sciences

Melanization as unfavorable factor in amelanotic melanoma cell biology

A. Skoniecka et al.

Summary: The biology of amelanotic melanoma cells from different species showed diverse responses to in vitro melanization induction, with hamster Ab cells undergoing intense melanization, mouse B16F10 cells darkening slightly, and human A375 cells showing no melanin production. The presence of melanin can have an impact on the behavior of melanoma cells.

PROTOPLASMA (2021)

Review Oncology

Neoantigen-Reactive T Cells: The Driving Force behind Successful Melanoma Immunotherapy

Lindy Davis et al.

Summary: Cancer immunotherapy revolutionizes cancer treatment by utilizing the patient's own immune system to fight and potentially cure cancer. T cells play a critical role in recognizing and killing tumor cells in melanoma patients by targeting neoantigens. Clinical trials have shown significant clinical responses in patients with metastatic cutaneous melanoma through checkpoint blockade immunotherapy or adoptive cell therapy.

CANCERS (2021)

Review Oncology

The evolution of human skin pigmentation involved the interactions of genetic, environmental, and cultural variables

Nina G. Jablonski

Summary: The evolution of human skin pigmentation is influenced by environmental ultraviolet radiation, with changes occurring multiple times as populations disperse and cultural practices develop. Skin pigmentation plays a key biological role in mediatiing the penetration of ultraviolet radiation into the deep layers of skin and the cutaneous circulation, and has been favored under conditions of high ultraviolet radiation.

PIGMENT CELL & MELANOMA RESEARCH (2021)

Article Biochemistry & Molecular Biology

Pigmentation Levels Affect Melanoma Responses to Coriolus versicolor Extract and Play a Crucial Role in Melanoma-Mononuclear Cell Crosstalk

Malgorzata Pawlikowska et al.

Summary: The presence of melanin pigment in melanoma cells inhibits their response to Coriolus versicolor extract, but susceptibility to cell death induced by the extract significantly increases after cell depigmentation. Inhibition of melanogenesis activates a necroptotic pathway in depigmented melanoma cells and modulates cytokine expression in co-cultured mononuclear cells, potentially enhancing host anticancer immunity.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Editorial Material Plant Sciences

Black is beautiful (and protective): melanin synthesis in animals and plants

Peter Nick

PROTOPLASMA (2021)

Review Ophthalmology

Retinal Pigment Epithelium Adenoma and Adenocarcinoma: A Review

Janani Sreenivasan et al.

Summary: Adenoma and adenocarcinoma of the retinal pigment epithelium are rare intraocular tumors that are often misdiagnosed as other lesions. It is crucial to differentiate them from melanoma because treatment options differ and melanoma requires lifelong follow-up for metastases screening.

OCULAR ONCOLOGY AND PATHOLOGY (2021)

Article Oncology

Relevance of Vitamin D in Melanoma Development, Progression and Therapy

Anna A. Brozyna et al.

ANTICANCER RESEARCH (2020)

Review Biochemistry & Molecular Biology

Significance of 5-S-Cysteinyldopa as a Marker for Melanoma

Kazumasa Wakamatsu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Multidisciplinary Sciences

A biomimetic approach to shielding from ionizing radiation: The case of melanized fungi

Thomas Vasileiou et al.

PLOS ONE (2020)

Article Biochemistry & Molecular Biology

Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy

Eva Perez-Guijarro et al.

NATURE MEDICINE (2020)

Article Biochemistry & Molecular Biology

The influence of iron on selected properties of synthetic pheomelanin

Andrzej Zadlo et al.

CELL BIOCHEMISTRY AND BIOPHYSICS (2020)

Review Neurosciences

Neuroblastoma - A Neural Crest Derived Embryonal Malignancy

John Inge Johnsen et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2019)

Article Multidisciplinary Sciences

Melanin presence inhibits melanoma cell spread in mice in a unique mechanical fashion

Michal Sarna et al.

SCIENTIFIC REPORTS (2019)

Review Biochemistry & Molecular Biology

Photodegradation of Eumelanin and Pheomelanin and Its Pathophysiological Implications

Shosuke Ito et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2018)

Review Oncology

Melanoma: What Do All the Mutations Mean?

Elizabeth J. Davis et al.

CANCER (2018)

Review Biochemistry & Molecular Biology

Transplantable Melanomas in Hamsters and Gerbils as Models for Human Melanoma. Sensitization in Melanoma Radiotherapy-From Animal Models to Clinical Trials

Martyna Sniegocka et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Editorial Material Biochemistry & Molecular Biology

Thermal Biology: Melanin-Based Energy Harvesting across the Tree of Life

Stefan Pinkert et al.

CURRENT BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Calcitriol and Calcidiol Can Sensitize Melanoma Cells to Low-LET Proton Beam Irradiation

Ewa Podgorska et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Biochemistry & Molecular Biology

Antiproliferative Activity of Non-Calcemic Vitamin D Analogs on Human Melanoma Lines in Relation to VDR and PDIA3 Receptors

Tomasz Wasiewicz et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Multidisciplinary Sciences

High response rate to PD-1 blockade in desmoplastic melanomas

Zeynep Eroglu et al.

NATURE (2018)

Review Endocrinology & Metabolism

How UV Light Touches the Brain and Endocrine System Through Skin, and Why

Andrzej T. Slominski et al.

ENDOCRINOLOGY (2018)

Editorial Material Dermatology

Does melanin matter in the dark?

Przemyslaw M. Plonka et al.

EXPERIMENTAL DERMATOLOGY (2017)

Review Medicine, Research & Experimental

Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management

Andrzej T. Slominski et al.

LABORATORY INVESTIGATION (2017)

Article Multidisciplinary Sciences

Melanosomal formation of PMEL core amyloid is driven by aromatic residues

Jia Shee Hee et al.

SCIENTIFIC REPORTS (2017)

Article Biochemistry & Molecular Biology

Paraquat-Melanin Redox-Cycling: Evidence from Electrochemical Reverse Engineering

Eunkyoung Kim et al.

ACS CHEMICAL NEUROSCIENCE (2016)

Article Pathology

UV-induced Melanin Chemiexcitation: A New Mode of Melanoma Pathogenesis

Douglas E. Brash

TOXICOLOGIC PATHOLOGY (2016)

Article Geosciences, Multidisciplinary

Why did life develop on the surface of the Earth in the Cambrian?

Carlo Doglioni et al.

GEOSCIENCE FRONTIERS (2016)

Editorial Material Dermatology

The role of melanin pigment in melanoma

Radomir M. Slominski et al.

EXPERIMENTAL DERMATOLOGY (2015)

Review Oncology

Melanins and melanogenesis: from pigment cells to human health and technological applications

Marco d'Ischia et al.

PIGMENT CELL & MELANOMA RESEARCH (2015)

Review Ophthalmology

Drosophila as a Potential Model for Ocular Tumors

Daimark Bennett et al.

OCULAR ONCOLOGY AND PATHOLOGY (2015)

Article Dermatology

Cell elasticity is an important indicator of the metastatic phenotype of melanoma cells

Michal Sarna et al.

EXPERIMENTAL DERMATOLOGY (2014)

Article Biochemistry & Molecular Biology

CYP24A1 Expression Inversely Correlates with Melanoma Progression: Clinic-Pathological Studies

Anna A. Brozyna et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

Editorial Material Medicine, General & Internal

Melanoma Resistance: A Bright Future for Academicians and a Challenge for Patient Advocates

Andrzej T. Slominski et al.

MAYO CLINIC PROCEEDINGS (2014)

Review Oncology

Pheomelanin-induced oxidative stress: bright and dark chemistry bridging red hair phenotype and melanoma

Alessandra Napolitano et al.

PIGMENT CELL & MELANOMA RESEARCH (2014)

Article Multidisciplinary Sciences

Proteomic Analysis of Proton Beam Irradiated Human Melanoma Cells

Sylwia Kedracka-Krok et al.

PLOS ONE (2014)

Article Surgery

The Role of Radiation Therapy in Melanoma

Jacqueline Oxenberg et al.

SURGICAL CLINICS OF NORTH AMERICA (2014)

Review Endocrinology & Metabolism

Key Role of CRF in the Skin Stress Response System

Andrzej T. Slominski et al.

ENDOCRINE REVIEWS (2013)

Article Oncology

Neutral pH and copper ions promote eumelanogenesis after the dopachrome stage

Shosuke Ito et al.

PIGMENT CELL & MELANOMA RESEARCH (2013)

Review Oncology

Melanins and melanogenesis: methods, standards, protocols

Marco d'Ischia et al.

PIGMENT CELL & MELANOMA RESEARCH (2013)

Review Oncology

L-tyrosine and L-dihydroxyphenylalanine as hormone-like regulators of melanocyte functions

Andrzej Slominski et al.

PIGMENT CELL & MELANOMA RESEARCH (2012)

Article Multidisciplinary Sciences

Direct chemical evidence for eumelanin pigment from the Jurassic period

Keely Glass et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Multidisciplinary Sciences

Specifying and Sustaining Pigmentation Patterns in Domestic and Wild Cats

Christopher B. Kaelin et al.

SCIENCE (2012)

Article Multidisciplinary Sciences

Melanoma induction by ultraviolet A but not ultraviolet B radiation requires melanin pigment

Frances P. Noonan et al.

NATURE COMMUNICATIONS (2012)

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Review Chemistry, Multidisciplinary

Chemical and Structural Diversity in Eumelanins: Unexplored Bio-Optoelectronic Materials

Marco d'Ischia et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)

Article Oncology

Tyrosinase Activated Melanoma Prodrugs

Samaila Jawaid et al.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2009)

Article Dermatology

Why do melanomas get so dark?

Rossitza Lazova et al.

EXPERIMENTAL DERMATOLOGY (2009)

Article Oncology

Independent regulation of hair and skin color by two G protein-coupled pathways

Catherine D. Van Raamsdonk et al.

PIGMENT CELL & MELANOMA RESEARCH (2009)

Article Biochemistry & Molecular Biology

Effect of untreated and photobleached bovine RPE melanosomes on the photoinduced peroxidation of lipids

Andrzej Zadlo et al.

PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES (2009)

Review Biochemistry & Molecular Biology

The origin and evolution of the neural crest

Philip C. J. Donoghue et al.

BIOESSAYS (2008)

Review Oncology

Tumor cell metabolism: Cancer's Achilles' heel

Guido Kroemer et al.

CANCER CELL (2008)

Article Biochemistry & Molecular Biology

Fas and FasL expression on cells of two transplantable melanoma lines according to their different biological properties

Katarzyna Zielinska et al.

FOLIA HISTOCHEMICA ET CYTOBIOLOGICA (2008)

Article Oncology

Inhibition of melanogenesis as a radiation sensitizer for melanoma therapy

Anna A. Brozyna et al.

INTERNATIONAL JOURNAL OF CANCER (2008)

Article Biochemistry & Molecular Biology

Sclerotia of the acellular (true) slime mould Fuligo septica as a model to study melanization and anabiosis

Anna Krzywda et al.

CELLULAR & MOLECULAR BIOLOGY LETTERS (2008)

Review Pharmacology & Pharmacy

Evaluation of HIF-1 inhibitors as anticancer agents

Gregg L. Semenza

DRUG DISCOVERY TODAY (2007)

Article Biochemistry & Molecular Biology

Photobleaching of melanosomes from retinal pigment epithelium: II. Effects on the response of living cells to photic stress

Mariusz Zareba et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2007)

Article Biochemistry & Molecular Biology

Photobleaching of melanosomes from retinal pigment epithelium: I. Effects on protein oxidation

Janice M. Burke et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2007)

Article Oncology

Reactive oxygen species: A breath of life or death?

John P. Fruehauf et al.

CLINICAL CANCER RESEARCH (2007)

Review Cell Biology

The physical and chemical properties of eumelanin

Paul Meredith et al.

PIGMENT CELL RESEARCH (2006)

Article Dermatology

Melanocortin receptor ligands:: New horizons for skin biology and clinical dermatology

Markus Boehm et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2006)

Article Biochemistry & Molecular Biology

Effects of photodegradation on the physical and antioxidant properties of melanosomes isolated from retinal pigment epithelium

Mariusz Zareba et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2006)

Article Biochemistry & Molecular Biology

Association of an Agouti allele with fawn or sable coat color in domestic dogs

TG Berryere et al.

MAMMALIAN GENOME (2005)

Article Biochemistry & Molecular Biology

Oxidation potentials of human eumelanosomes and plheomelanosomes

A Samokhvalov et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2005)

Review Dermatology

Hair follicle pigmentation

A Slominski et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2005)

Review Physiology

Melanin pigmentation in mammalian skin and its hormonal regulation

A Slominski et al.

PHYSIOLOGICAL REVIEWS (2004)

Article Dermatology

BRAF mutation -: A frequent event in benign, atypical, and malignant melanocytic lesions of the skin

P Uribe et al.

AMERICAN JOURNAL OF DERMATOPATHOLOGY (2003)

Article Cell Biology

Melanogenesis and melanoma

PA Riley

PIGMENT CELL RESEARCH (2003)

Article Cell Biology

Rate constants for the first two chemical steps of eumelanogenesis

EJ Land et al.

PIGMENT CELL RESEARCH (2003)

Article Dermatology

Transplantable melanomas in gerbils (meriones unguiculatus). II: melanogenesis

PM Plonka et al.

EXPERIMENTAL DERMATOLOGY (2003)

Article Cell Biology

A chemist's view of melanogenesis

S Ito

PIGMENT CELL RESEARCH (2003)

Review Chemistry, Multidisciplinary

Tyrosinase autoactivation and the chemistry of ortho-quinone amines

EJ Land et al.

ACCOUNTS OF CHEMICAL RESEARCH (2003)

Article Multidisciplinary Sciences

Dominant role of the niche in melanocyte stem-cell fate determination

EK Nishimura et al.

NATURE (2002)

Article Cell Biology

The expression of corticotropin-releasing hormone in melanoma

H Sato et al.

PIGMENT CELL RESEARCH (2002)

Article Biochemistry & Molecular Biology

Ultrastructural organization of eumelanin from Sepia officinalis measured by atomic force microscopy

CMR Clancy et al.

BIOCHEMISTRY (2001)

Review Immunology

Immunotherapy of melanoma

C Smith et al.

IMMUNOLOGY (2001)

Review Endocrinology & Metabolism

Neuroendocrinology of the skin

A Slominski et al.

ENDOCRINE REVIEWS (2000)

Article Cell Biology

UVA, pheomelanin and the carcinogenesis of melanoma

HZ Hill et al.

PIGMENT CELL RESEARCH (2000)