4.6 Article

Integrative Dissection of Novel Lactate Metabolism-Related Signature in the Tumor Immune Microenvironment and Prognostic Prediction in Breast Cancer

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Oncology

The oncogenic and clinical implications of lactate induced immunosuppression in the tumour microenvironment

Conall Hayes et al.

Summary: The tumor microenvironment plays a critical role in cancer development and progression, with lactate accumulation actively contributing to immune evasion. Measuring lactate levels in tumors has shown promise as a predictive and prognostic biomarker in various cancer types. Targeting lactate metabolism may be a priority in developing effective cancer therapies, although success in human trials has been limited so far due to the complexities of metabolic interactions.

CANCER LETTERS (2021)

Article Oncology

Downregulation of RPS14 inhibits the proliferation and metastasis of estrogen receptor-positive breast cancer cells

Xiu Wang et al.

Summary: RPS14 is highly expressed in ER+ breast cancer tissues, and its downregulation significantly inhibits the proliferation, cycle, and metastasis of breast cancer cells, while inducing apoptosis. Several significant genes are altered in breast cancer cells after RPS14 downregulation, with BAG2 and interferon signaling pathways being identified as significantly activated.

ANTI-CANCER DRUGS (2021)

Review Immunology

Lactate modulation of immune responses in inflammatory versus tumour microenvironments

Michelangelo Certo et al.

Summary: The microenvironments of cancerous tissues and tissues affected by chronic inflammatory diseases exhibit different immune states but similar metabolic states. Understanding the metabolic signature allows for therapeutic intervention to reset metabolite availability and correct dysregulated immune states.

NATURE REVIEWS IMMUNOLOGY (2021)

Article Oncology

Lactate concentration in breast cancer using advanced magnetic resonance spectroscopy

Sai Man Cheung et al.

BRITISH JOURNAL OF CANCER (2020)

Article Cell Biology

Intratumor lactate levels reflect HER2 addiction status in HER2-positive breast cancer

Lorenzo Castagnoli et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

Article Biochemistry & Molecular Biology

SLC19A1 Is an Importer of the Immunotransmitter cGAMP

Christopher Ritchie et al.

MOLECULAR CELL (2019)

Review Oncology

The Tumor Microenvironment Innately Modulates Cancer Progression

Dominique C. Hinshaw et al.

CANCER RESEARCH (2019)

Article Multidisciplinary Sciences

SLC19A1 transports immunoreactive cyclic dinucleotides

Rutger D. Luteijn et al.

NATURE (2019)

Article Biochemistry & Molecular Biology

Maftools: efficient and comprehensive analysis of somatic variants in cancer

Anand Mayakonda et al.

GENOME RESEARCH (2018)

Review Cell Biology

Unravelling the Interplay between Extracellular Acidosis and Immune Cells

Fernando Erra Diaz et al.

MEDIATORS OF INFLAMMATION (2018)

Review Oncology

Breast Cancer Immunotherapy: Facts and Hopes

Leisha A. Emens

CLINICAL CANCER RESEARCH (2018)

Review Medicine, General & Internal

Discrimination and Calibration of Clinical Prediction Models Users' Guides to the Medical Literature

Ana Carolina Alba et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)

Article Multidisciplinary Sciences

Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis

Peiwen Chen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Oncology

Drawing Nomograms with R: applications to categorical outcome and survival data

Zhongheng Zhang et al.

ANNALS OF TRANSLATIONAL MEDICINE (2017)

Article Biotechnology & Applied Microbiology

CYC1 Predicts Poor Prognosis in Patients with Breast Cancer

Yingyan Han et al.

DISEASE MARKERS (2016)

Article Biochemical Research Methods

Robust enumeration of cell subsets from tissue expression profiles

Aaron M. Newman et al.

NATURE METHODS (2015)

Article Biochemical Research Methods

GSVA: gene set variation analysis for microarray and RNA-Seq data

Sonja Haenzelmann et al.

BMC BIOINFORMATICS (2013)

Article Biochemical Research Methods

RCircos: an R package for Circos 2D track plots

Hongen Zhang et al.

BMC BIOINFORMATICS (2013)

Article Biochemistry & Molecular Biology

Ribosomal Protein S14 Negatively Regulates c-Myc Activity

Xiang Zhou et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Multidisciplinary Sciences

Inferring tumour purity and stromal and immune cell admixture from expression data

Kosuke Yoshihara et al.

NATURE COMMUNICATIONS (2013)

Article Biochemistry & Molecular Biology

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

Davis J. McCarthy et al.

NUCLEIC ACIDS RESEARCH (2012)

Review Oncology

Lactate: A Metabolic Key Player in Cancer

Franziska Hirschhaeuser et al.

CANCER RESEARCH (2011)

Article Oncology

Metabolic and proteomic differentials in head and neck squamous cell carcinomas and normal gingival tissue

Thomas Ziebart et al.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2011)

Article Oncology

Glycolytic metabolism and tumour response to fractionated irradiation

Ulrike G. A. Sattler et al.

RADIOTHERAPY AND ONCOLOGY (2010)

Review Oncology

Cytokines in cancer pathogenesis and cancer therapy

G Dranoff

NATURE REVIEWS CANCER (2004)