相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。
Article
Cell Biology
Ibrahim Morgan et al.
Summary: Anthraquinone derivatives are a class of compounds that exhibit various biological activities, including antifungal, antibacterial, antiviral, and anticancer activities. This study tested various synthetic anthraquinone derivatives against different cancer cell lines and found that most of them exhibit anticancer effects. One specific compound, 1,4-bis(benzyloxy)-2,3-bis(hydroxymethyl)anthracene-9,10-dione, exhibited the highest cytotoxicity against PC3 cells and was further investigated for its mechanism of action. The compound was found to induce apoptosis, disrupt cellular equilibrium, and cause cell cycle arrest.
Article
Cell Biology
Francesco Brunelli et al.
Summary: In this study, a novel anti-apoptotic function of PINK1 was discovered, providing new options for treatment in proliferative or neurodegenerative diseases.
Review
Cell Biology
Alessandra Ida Celia et al.
Summary: Autophagy and apoptosis play important roles in rheumatic diseases, and the dysregulation of their balance may contribute to the development of these diseases. Understanding the mechanisms of autophagy is of great significance for the research and treatment of rheumatic diseases.
Article
Cell Biology
Valeria Manganelli et al.
Summary: This study investigates the association of ERLIN1 with MAM raft-like microdomains and its interaction with AMBRA1 in regulating autophagy. The interaction between ERLIN1 and AMBRA1 at MAM raft-like microdomains is crucial for autophagosome formation.
Article
Cell Biology
Deokha Kim et al.
Summary: Regulation of the PGC1α: BNIP3 mitophagy axis may have therapeutic benefits for cartilage-degrading diseases.
Article
Cell Biology
Wojciech Trybus et al.
Summary: Physcion exerts antitumor effects by inducing oxidative stress, autophagy, and apoptosis in HeLa cells, resulting in decreased cell viability, G0/G1 phase cell cycle arrest, and activation of the lysosomal system.
Review
Cell Biology
Pramod Sukumaran et al.
Summary: Calcium serves as a crucial second messenger in regulating various physiological functions, such as cell growth/development, cell survival, and programmed cell death processes. The homeostasis of cytosolic calcium levels, maintained through coordination of proteins/pumps/Ca2+ channels and Ca2+ storage in organelles, is essential for cellular functions. Store operated Ca2+ entry (SOCE) mechanism, activated by calcium depletion, influences functions in both excitable and non-excitable cells, with potential implications in neurodegenerative conditions.
Review
Cell Biology
Valeria Manganelli et al.
Summary: ERLINs are a family of proteins involved in ER-associated protein degradation and regulation of lipid metabolism. They have been traditionally considered markers of ER lipid raft-like microdomains but have also been found in mitochondria-associated endoplasmic reticulum membranes (MAMs) under pathophysiological conditions, influencing cell fate by regulating processes such as survival and death. Their alteration can significantly impact the pathogenesis of various human diseases.
Review
Cell Biology
Erdinc Sezgin et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY
(2017)
Article
Biochemistry & Molecular Biology
Tina Garofalo et al.
Article
Multidisciplinary Sciences
Erdinc Sezgin et al.
